Nanoparticle mediated silencing of DNA repair sensitizes pediatric brain tumor cells to γ-irradiation

Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy

(2015) Rachel Abbotts et al.   Oncotarget

Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity

(2014) Kathryn A. Whitehead et al.   Nature Communications

Targeted Cell Uptake of a Noninternalizing Antibody Through Conjugation to Iron Oxide Nanoparticles in Primary Central Nervous System Lymphoma

(2013) Tingzhong Wang et al.   World Neurosurgery

Identification and Characterization of Human Apurinic/Apyrimidinic Endonuclease-1 Inhibitors

(2012) Ajay Srinivasan et al.   BIOCHEMISTRY

Molecular approaches to ependymoma

(2012) Hendrik Witt et al.   CURRENT OPINION IN NEUROLOGY

Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors

(2012) Rebeka Sultana et al.   INTERNATIONAL JOURNAL OF CANCER

Hyperfractionated Versus Conventional Radiotherapy Followed by Chemotherapy in Standard-Risk Medulloblastoma: Results From the Randomized Multicenter HIT-SIOP PNET 4 Trial

(2012) Birgitta Lannering et al.   JOURNAL OF CLINICAL ONCOLOGY

Fabrication of magnetic nanoparticles with controllable drug loading and release through a simple assembly approach

(2012) Chen Fang et al.   JOURNAL OF CONTROLLED RELEASE

The DNA damage response and cancer therapy

(2012) Christopher J. Lord et al.   NATURE

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2005-2009

(2012) T. A. Dolecek et al.   NEURO-ONCOLOGY

Diverse Small Molecule Inhibitors of Human Apurinic/Apyrimidinic Endonuclease APE1 Identified from a Screen of a Large Public Collection

(2012) Dorjbal Dorjsuren et al.   PLoS One

Surface Engineering of Iron Oxide Nanoparticles for Targeted Cancer Therapy

(2011) Forrest M. Kievit et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cancer Nanotheranostics: Improving Imaging and Therapy by Targeted Delivery Across Biological Barriers

(2011) Forrest M. Kievit et al.   ADVANCED MATERIALS

Apurinic/apyrimidinic endonuclease is inversely associated with response to radiotherapy in pediatric ependymoma

(2011) Michael S. Bobola et al.   INTERNATIONAL JOURNAL OF CANCER

Small-Molecule Inhibitors of APE1 DNA Repair Function: An Overview

(2011) Rasha I. Al-Safi et al.   Current Molecular Pharmacology

APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1

(2011) Mark R. Kelley et al.   Current Molecular Pharmacology

Chlorotoxin Labeled Magnetic Nanovectors for Targeted Gene Delivery to Glioma

(2010) Forrest M. Kievit et al.   ACS Nano

Chlorotoxin bound magnetic nanovector tailored for cancer cell targeting, imaging, and siRNA delivery

(2010) Omid Veiseh et al.   BIOMATERIALS

Human AP endonuclease 1 (APE1): From mechanistic insights to druggable target in cancer

(2010) Rachel Abbotts et al.   CANCER TREATMENT REVIEWS

Small molecule inhibitors of DNA repair nuclease activities of APE1

(2010) David M. Wilson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Distinct Roles of Ape1 Protein in the Repair of DNA Damage Induced by Ionizing Radiation or Bleomycin

(2010) Hua Fung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

pH-Sensitive siRNA Nanovector for Targeted Gene Silencing and Cytotoxic Effect in Cancer Cells

(2010) Hyejung Mok et al.   MOLECULAR PHARMACEUTICS

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

PEI-PEG-Chitosan-Copolymer-Coated Iron Oxide Nanoparticles for Safe Gene Delivery: Synthesis, Complexation, and Transfection

(2009) Forrest M. Kievit et al.   ADVANCED FUNCTIONAL MATERIALS

Specific Targeting of Brain Tumors with an Optical/Magnetic Resonance Imaging Nanoprobe across the Blood-Brain Barrier

(2009) O. Veiseh et al.   CANCER RESEARCH

DNA Repair in Mammalian Cells

(2009) A. B. Robertson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Survival following treatment for intracranial ependymoma: a review

(2009) G. Tamburrini et al.   CHILDS NERVOUS SYSTEM

Pediatric Ependymoma: Biological Perspectives

(2009) J.-P. Kilday et al.   MOLECULAR CANCER RESEARCH

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Pediatric brain tumors: Current treatment strategies and future therapeutic approaches

(2009) Sabine Mueller et al.   Neurotherapeutics

Size-Dependent Endocytosis of Nanoparticles

(2008) Sulin Zhang et al.   ADVANCED MATERIALS

Genetically Engineered Mouse Models of Brain Cancer and the Promise of Preclinical Testing

(2008) Jason T. Huse et al.   BRAIN PATHOLOGY