A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis

Do we need a new vaccine to control the re-emergence of pertussis?

(2015) Kingston H.G. Mills et al.   TRENDS IN MICROBIOLOGY

A Promiscuous Lipid-Binding Protein Diversifies the Subcellular Sites of Toll-like Receptor Signal Transduction

(2014) Kevin S. Bonham et al.   CELL

TIRAP C539T polymorphism contributes to tuberculosis susceptibility: Evidence from a meta-analysis

(2014) Qianqian Liu et al.   INFECTION GENETICS AND EVOLUTION

Different Effects of Whole-Cell and Acellular Vaccines on Bordetella Transmission

(2014) William E. Smallridge et al.   JOURNAL OF INFECTIOUS DISEASES

Mal, more than a bridge to MyD88

(2013) Nicholas J. Bernard et al.   IUBMB LIFE

Identification of Binding Sites for Myeloid Differentiation Primary Response Gene 88 (MyD88) and Toll-like Receptor 4 in MyD88 Adapter-like (Mal)

(2013) Celia Bovijn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

(2013) H. E. Ghoneim et al.   JOURNAL OF IMMUNOLOGY

MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C

(2013) S C Corr et al.   Mucosal Immunology

Non-Essential Role for TLR2 and Its Signaling Adaptor Mal/TIRAP in Preserving Normal Lung Architecture in Mice

(2013) Saleela M. Ruwanpura et al.   PLoS One

Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model

(2013) J. M. Warfel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lung dendritic cells facilitate extrapulmonary bacterial dissemination during pneumococcal pneumonia

(2013) Alva Rosendahl et al.   Frontiers in Cellular and Infection Microbiology

Association of Mal/TIRAP S180L variant polymorphism with decreased infection risk in patients with advanced HIV-1 infection

(2012) Antonios I. Papadopoulos et al.   CYTOKINE

Toll like receptors in diseases of the lung

(2011) Melissa A. Kovach et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

IRAK1 and IRAK4 Promote Phosphorylation, Ubiquitination, and Degradation of MyD88 Adaptor-like (Mal)

(2010) Aisling Dunne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-1 targets the TLR adaptor Mal at a crucial TIR-domain interaction site

(2010) P. Ulrichts et al.   JOURNAL OF CELL SCIENCE

Global, regional, and national causes of child mortality in 2008: a systematic analysis

(2010) Robert E Black et al.   LANCET

CD11c+CD8 + Dendritic Cells Promote Protective Immunity to Respiratory Infection with Bordetella pertussis

(2009) P. J. Dunne et al.   JOURNAL OF IMMUNOLOGY

Heterozygosity for the S180L Variant ofMAL/TIRAP,a Gene Expressing an Adaptor Protein in the Toll‐Like Receptor Pathway, Is Associated with Lower Risk of Developing Chronic Chagas Cardiomyopathy

(2009) Rajendranath Ramasawmy et al.   JOURNAL OF INFECTIOUS DISEASES

TIRAP (MAL) S180L polymorphism is a common protective factor against developing tuberculosis and systemic lupus erythematosus

(2008) John Castiblanco et al.   INFECTION GENETICS AND EVOLUTION