MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C

Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2 and antibacterial peptides

(2012) A L Frantz et al.   Mucosal Immunology

Protein kinase Cζ phosphorylates occludin and promotes assembly of epithelial tight junctions

(2011) Suneet Jain et al.   BIOCHEMICAL JOURNAL

Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease

(2011) Clara Abraham et al.   GASTROENTEROLOGY

Activation of TLR2 Enhances Tight Junction Barrier in Epidermal Keratinocytes

(2011) T. Yuki et al.   JOURNAL OF IMMUNOLOGY

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Hydroxylase inhibition attenuates colonic epithelial secretory function and ameliorates experimental diarrhea

(2010) Joseph B. J. Ward et al.   FASEB JOURNAL

The Dual Role of Zonula Occludens (ZO) Proteins

(2010) H. Bauer et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC)

(2010) Laurie E. Kilpatrick et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Toll-like receptor 4 differentially regulates epidermal growth factor-related growth factors in response to intestinal mucosal injury

(2010) David Hsu et al.   LABORATORY INVESTIGATION

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands

(2010) K. Brandl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Nod1 in Mucosal Dendritic Cells during Salmonella Pathogenicity Island 1-Independent Salmonella enterica Serovar Typhimurium Infection

(2009) L. Le Bourhis et al.   INFECTION AND IMMUNITY

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crosstalk of tight junction components with signaling pathways

(2007) Lorenza González-Mariscal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The cytoplasmic plaque of tight junctions: A scaffolding and signalling center

(2007) Laurent Guillemot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis

(2007) D. L. Gibson et al.   CELLULAR MICROBIOLOGY

Expression of Toll/IL-1R domain-containing adaptor protein (TIRAP) is detrimental to primary clearance of Salmonella and is not required for the generation of protective immunity

(2007) Stu Jerke et al.   IMMUNOLOGY LETTERS