Roasted Coffee Reduces β-Amyloid Production by Increasing Proteasomal β-Secretase Degradation in Human Neuroblastoma SH-SY5Y Cells

BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology

(2018) Finn Peters et al.   ACTA NEUROPATHOLOGICA

Caffeine Synergizes with Another Coffee Component to Increase Plasma GCSF: Linkage to Cognitive Benefits in Alzheimer's Mice

(2018) Chuanhai Cao et al.   JOURNAL OF ALZHEIMERS DISEASE

Beta-secretase inhibitors in phase I and phase II clinical trials for Alzheimer’s disease

(2017) Charbel E-H. Moussa   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Relationships of Dietary Patterns, Foods, and Micro- and Macronutrients with Alzheimer’s Disease and Late-Life Cognitive Disorders: A Systematic Review

(2017) Vincenzo Solfrizzi et al.   JOURNAL OF ALZHEIMERS DISEASE

BACE1 Inhibitor Lanabecestat (AZD3293) in a Phase 1 Study of Healthy Japanese Subjects: Pharmacokinetics and Effects on Plasma and Cerebrospinal Fluid Aβ Peptides

(2017) Kei Sakamoto et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Midlife Coffee and Tea Drinking and the Risk of Late-Life Dementia: A Population-Based CAIDE Study

(2017) Marjo H. Eskelinen et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-β Levels in Aged Alzheimer's Disease Mice

(2017) Gary W. Arendash et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine and Coffee as Therapeutics Against Alzheimer's Disease

(2017) Gary W. Arendash et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine Intake and Dementia: Systematic Review and Meta-Analysis

(2017) Catarina Santos et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer’s therapy targeting the β-secretase enzyme BACE1: Benefits and potential limitations from the perspective of animal model studies

(2016) Masuo Ohno   BRAIN RESEARCH BULLETIN

The Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer’s Disease and Spinal Cord Injury

(2016) Bing Gong et al.   Frontiers in Molecular Neuroscience

cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins

(2015) Sudarsanareddy Lokireddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gas Chromatography Time-Of-Flight Mass Spectrometry (GC-TOF-MS)-Based Metabolomics for Comparison of Caffeinated and Decaffeinated Coffee and Its Implications for Alzheimer’s Disease

(2014) Kai Lun Chang et al.   PLoS One

Ubiquitin pathways in neurodegenerative disease

(2014) Graham Atkin et al.   Frontiers in Molecular Neuroscience

Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging

(2013) Barbara Shukitt-Hale et al.   AGE

Relationship between amyloid-beta and the ubiquitin–proteasome system in Alzheimer’s disease

(2013) Liang Hong et al.   NEUROLOGICAL RESEARCH

Crude caffeine reduces memory impairment and amyloid β1–42 levels in an Alzheimer’s mouse model

(2012) Yi-Fang Chu et al.   FOOD CHEMISTRY

Caffeine induces beneficial changes in PKA signaling and JNK and ERK activities in the striatum and cortex of Alzheimer's transgenic mice

(2011) Ross Zeitlin et al.   BRAIN RESEARCH