Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies

Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity

(2018) Franziska Kundel et al.   ACS Chemical Biology

Inert and seed-competent tau monomers suggest structural origins of aggregation

(2018) Hilda Mirbaha et al.   eLife

Transcranial Laser Therapy Attenuates Amyloid-β Peptide Neuropathology in Amyloid-β Protein Precursor Transgenic Mice

(2018) Luis De Taboada et al.   JOURNAL OF ALZHEIMERS DISEASE

Molecular Mechanisms Underlying Neuroprotective Effect of Intranasal Administration of Human Hsp70 in Mouse Model of Alzheimer’s Disease

(2017) Michail B. Evgen’ev et al.   JOURNAL OF ALZHEIMERS DISEASE

Tau association with synaptic vesicles causes presynaptic dysfunction

(2017) Lujia Zhou et al.   Nature Communications

Near infrared light decreases synaptic vulnerability to amyloid beta oligomers

(2017) Michele M. Comerota et al.   Scientific Reports

A method to determine insulin responsiveness in synaptosomes isolated from frozen brain tissue

(2016) Whitney Franklin et al.   JOURNAL OF NEUROSCIENCE METHODS

NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies

(2016) Yousuf O. Ali et al.   PLOS BIOLOGY

Specific Targeting of Tau Oligomers in Htau Mice Prevents Cognitive Impairment and Tau Toxicity Following Injection with Brain-Derived Tau Oligomeric Seeds

(2016) Diana L. Castillo-Carranza et al.   JOURNAL OF ALZHEIMERS DISEASE

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

(2016) M. Fá et al.   Scientific Reports

Internalized Tau Oligomers Cause Neurodegeneration by Inducing Accumulation of Pathogenic Tau in Human Neurons Derived from Induced Pluripotent Stem Cells

(2015) M. Usenovic et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies

(2014) David W. Sanders et al.   NEURON

Promoting Autophagic Clearance: Viable Therapeutic Targets in Alzheimer’s Disease

(2014) Lauren G. Friedman et al.   Neurotherapeutics

Lost after translation: missorting of Tau protein and consequences for Alzheimer disease

(2014) Hans Zempel et al.   TRENDS IN NEUROSCIENCES

Photobiomodulation with near infrared light mitigates Alzheimer’s disease-related pathology in cerebral cortex – evidence from two transgenic mouse models

(2014) Sivaraman Purushothuman et al.   Alzheimers Research & Therapy

Heat shock proteins in neurodegenerative disorders and aging

(2014) Rehana K. Leak   Journal of Cell Communication and Signaling

Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer’s disease

(2014) Hwan-Ching Tai et al.   Acta Neuropathologica Communications

The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives

(2013) Russell H. Swerdlow et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Non-invasive infra-red therapy (1072nm) reduces β-amyloid protein levels in the brain of an Alzheimer’s disease mouse model, TASTPM

(2013) S.L. Grillo et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

(2013) Ji Won Um et al.   NEURON

Autophagic/lysosomal dysfunction in Alzheimer’s disease

(2013) Miranda E Orr et al.   Alzheimers Research & Therapy

Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

(2012) Cristian A. Lasagna-Reeves et al.   FASEB JOURNAL

Imbalance of Hsp70 family variants fosters tau accumulation

(2012) Umesh K. Jinwal et al.   FASEB JOURNAL

Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease

(2011) H. Rheinallt Parri et al.   BIOCHEMICAL PHARMACOLOGY

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

Preparation and Characterization of Neurotoxic Tau Oligomers

(2010) Cristian A. Lasagna-Reeves et al.   BIOCHEMISTRY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Amyloid-β oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice

(2010) Kelly T. Dineley et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease

(2010) H.N. Dawson et al.   NEUROSCIENCE

Mitochondrial Mechanisms of Photobiomodulation in Context of New Data About Multiple Roles of ATP

(2010) Tiina Karu   PHOTOMEDICINE AND LASER SURGERY

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

(2008) L. M. Ittner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA