RSPO3 impairs barrier function of human vascular endothelial monolayers and synergizes with pro-inflammatory IL-1

Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells

(2018) HyunTae V. Hwang et al.   PLoS One

WIF1 prevents Wnt5A mediated LIMK/CFL phosphorylation and adherens junction disruption in human vascular endothelial cells

(2017) Tom Skaria et al.   Journal of Inflammation-London

Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits

(2017) Ryan G. Lim et al.   Cell Reports

Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca 2+ /NFAT Signaling

(2016) Beate Scholz et al.   DEVELOPMENTAL CELL

IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling

(2016) Tom Skaria et al.   PLoS One

Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins

(2016) Harmen van Andel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt5A/Ryk signaling critically affects barrier function in human vascular endothelial cells

(2016) Tom Skaria et al.   Cell Adhesion & Migration

Anti-Cancer Stem-like Cell Compounds in Clinical Development – An Overview and Critical Appraisal

(2016) Fabrizio Marcucci et al.   Frontiers in Oncology

R-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice

(2016) Eugene Kang et al.   PLoS One

Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates  -Catenin Signaling and Tumorigenesis in Multiple Cancer Types

(2015) C. Chartier et al.   CANCER RESEARCH

Endothelial Alpha-Parvin Controls Integrity of Developing Vasculature and Is Required for Maintenance of Cell-Cell Junctions

(2015) A. Fraccaroli et al.   CIRCULATION RESEARCH

R-spondins: Novel matricellular regulators of the skeleton

(2014) M. Noelle Knight et al.   MATRIX BIOLOGY

A critical role for Lyn kinase in strengthening endothelial integrity and barrier function

(2013) J. Han et al.   BLOOD

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

Cyclic AMP response element-binding protein prevents endothelial permeability increase through transcriptional controlling p190RhoGAP expression

(2011) K. R. Chava et al.   BLOOD

Bone morphogenetic protein receptor II regulates pulmonary artery endothelial cell barrier function

(2010) V. J. Burton et al.   BLOOD

Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier

(2010) Michael J Bernas et al.   Nature Protocols

Transmigration across activated endothelium induces transcriptional changes, inhibits apoptosis, and decreases antimicrobial protein expression in human monocytes

(2009) Marcie R. Williams et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Regulation of Endothelial Junctional Permeability

(2008) Emily Vandenbroucke et al.   Annals of the New York Academy of Sciences

Vascular permeability in cardiovascular disease and cancer

(2008) Sara M Weis   CURRENT OPINION IN HEMATOLOGY