Neighbor communities in drug combination networks characterize synergistic effect
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Title
Neighbor communities in drug combination networks characterize synergistic effect
Authors
Keywords
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Journal
Molecular BioSystems
Volume 8, Issue 12, Pages 3185
Publisher
Royal Society of Chemistry (RSC)
Online
2012-09-05
DOI
10.1039/c2mb25267h
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- Interactome Networks and Human Disease
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- (2011) Elie Dolgin NATURE MEDICINE
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- (2011) Janet Woodcock et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2011) F. Zhu et al. NUCLEIC ACIDS RESEARCH
- The IntAct molecular interaction database in 2012
- (2011) S. Kerrien et al. NUCLEIC ACIDS RESEARCH
- KEGG for integration and interpretation of large-scale molecular data sets
- (2011) M. Kanehisa et al. NUCLEIC ACIDS RESEARCH
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- (2011) A. Gaulton et al. NUCLEIC ACIDS RESEARCH
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- (2009) Gregor Jansen et al. Molecular Systems Biology
- Systems pathology—taking molecular pathology into a new dimension
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- (2008) Sheng-Yong Yang et al. ARTIFICIAL INTELLIGENCE IN MEDICINE
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- Human Protein Reference Database--2009 update
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