PZR Coordinates Shp2 Noonan and LEOPARD Syndrome Signaling in Zebrafish and Mice

Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (PTPN11)

(2014) Wei Qiu et al.   BMC STRUCTURAL BIOLOGY

Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations

(2013) Zhi-Hong Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTMScan Direct: Identification and Quantification of Peptides from Critical Signaling Proteins by Immunoaffinity Enrichment Coupled with LC-MS/MS

(2012) Matthew P. Stokes et al.   MOLECULAR & CELLULAR PROTEOMICS

Noonan syndrome gain-of-function mutations in NRAS cause zebrafish gastrulation defects

(2011) V. Runtuwene et al.   Disease Models & Mechanisms

RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it

(2011) Bruce D. Gelb et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome–associated PTPN11 mutation

(2011) Talita M. Marin et al.   JOURNAL OF CLINICAL INVESTIGATION

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

RPTPα and PTPε signaling via Fyn/Yes and RhoA is essential for zebrafish convergence and extension cell movements during gastrulation

(2010) Mark van Eekelen et al.   DEVELOPMENTAL BIOLOGY

Phosphatase-Dependent and -Independent Functions of Shp2 in Neural Crest Cells Underlie LEOPARD Syndrome Pathogenesis

(2010) Rodney A. Stewart et al.   DEVELOPMENTAL CELL

Genetic Analyses of Integrin Signaling

(2010) S. A. Wickstrom et al.   Cold Spring Harbor Perspectives in Biology

Phosphorylation and Localization of Protein-Zero Related (PZR) in Cultured Endothelial Cells

(2008) Ken-ichi Kusano et al.   ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH

Noonan, Costello and cardio–facio–cutaneous syndromes: dysregulation of the Ras–MAPK pathway

(2008) William E. Tidyman et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Noonan Syndrome-associated SHP-2/Ptpn11Mutants Enhance SIRPα and PZR Tyrosyl Phosphorylation and Promote Adhesion-mediated ERK Activation

(2008) Seda Eminaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling networks assembled by oncogenic EGFR and c-Met

(2008) A. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA