PTMScan Direct: Identification and Quantification of Peptides from Critical Signaling Proteins by Immunoaffinity Enrichment Coupled with LC-MS/MS

A Novel ALK Secondary Mutation and EGFR Signaling Cause Resistance to ALK Kinase Inhibitors

(2011) T. Sasaki et al.   CANCER RESEARCH

Combinatorial Treatments That Overcome PDGFR -Driven Resistance of Melanoma Cells to V600EB-RAF Inhibition

(2011) H. Shi et al.   CANCER RESEARCH

Ubiquitin Ligase Substrate Identification through Quantitative Proteomics at Both the Protein and Peptide Levels

(2011) Kimberly A. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Advances in top-down proteomics for disease biomarker discovery

(2011) David Calligaris et al.   Journal of Proteomics

Deep and Highly Sensitive Proteome Coverage by LC-MS/MS Without Prefractionation

(2011) Suman S. Thakur et al.   MOLECULAR & CELLULAR PROTEOMICS

Evaluation of Large Scale Quantitative Proteomic Assay Development Using Peptide Affinity-based Mass Spectrometry

(2011) Jeffrey R. Whiteaker et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantitative Chemical Proteomics Reveals New Potential Drug Targets in Head and Neck Cancer

(2011) Zhixiang Wu et al.   MOLECULAR & CELLULAR PROTEOMICS

Assessing the Activity of Cediranib, a VEGFR-2/3 Tyrosine Kinase Inhibitor, against VEGFR-1 and Members of the Structurally Related PDGFR Family

(2011) S. R. Brave et al.   MOLECULAR CANCER THERAPEUTICS

Absolute quantification of microbial proteomes at different states by directed mass spectrometry

(2011) A. Schmidt et al.   Molecular Systems Biology

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

(2011) Xose S. Puente et al.   NATURE

mProphet: automated data processing and statistical validation for large-scale SRM experiments

(2011) Lukas Reiter et al.   NATURE METHODS

Large-scale phosphosite quantification in tissues by a spike-in SILAC method

(2011) Mara Monetti et al.   NATURE METHODS

Catch me if you can: Mass spectrometry-based phosphoproteomics and quantification strategies

(2011) Beate Eyrich et al.   PROTEOMICS

System-Wide Temporal Characterization of the Proteome and Phosphoproteome of Human Embryonic Stem Cell Differentiation

(2011) K. T. G. Rigbolt et al.   Science Signaling

Biomarkers of chemotherapy resistance in breast cancer identified by proteomics: Current status

(2010) Victoria C. Hodgkinson et al.   CANCER LETTERS

Regulation of Protein Kinase C function by phosphorylation on conserved and non-conserved sites

(2010) Michael Freeley et al.   CELLULAR SIGNALLING

The GIST paradigm: lessons for other kinase-driven cancers

(2010) Cristina R Antonescu   JOURNAL OF PATHOLOGY

Phosphoproteomic characterization of PYK2 signaling pathways involved in osteogenesis

(2010) Peter C. Bonnette et al.   Journal of Proteomics

Proteomics on an Orbitrap Benchtop Mass Spectrometer Using All-ion Fragmentation

(2010) Tamar Geiger et al.   MOLECULAR & CELLULAR PROTEOMICS

Diverse somatic mutation patterns and pathway alterations in human cancers

(2010) Zhengyan Kan et al.   NATURE

Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling

(2010) Guoqiang Xu et al.   NATURE BIOTECHNOLOGY

Decoding signalling networks by mass spectrometry-based proteomics

(2010) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Akt-RSK-S6 Kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases

(2010) A. Moritz et al.   Science Signaling

Application of array-based whole genome scanning technologies as a cytogenetic tool in haematological malignancies

(2009) Jaroslaw P. Maciejewski et al.   BRITISH JOURNAL OF HAEMATOLOGY

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

(2009) Ji Luo et al.   CELL

FLT3 inhibition and mechanisms of drug resistance in mutant FLT3-positive AML

(2009) Ellen Weisberg et al.   DRUG RESISTANCE UPDATES

A Human Proteome Detection and Quantitation Project

(2009) N. Leigh Anderson et al.   MOLECULAR & CELLULAR PROTEOMICS

Single nucleotide polymorphism arrays: a decade of biological, computational and technological advances

(2009) T. LaFramboise   NUCLEIC ACIDS RESEARCH

Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors

(2009) A F Gazdar   ONCOGENE

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Combining Protein-Based IMAC, Peptide-Based IMAC, and MudPIT for Efficient Phosphoproteomic Analysis

(2008) Greg T. Cantin et al.   JOURNAL OF PROTEOME RESEARCH

Enrichment of Phosphopeptides by Fe3+-Immobilized Magnetic Nanoparticles for Phosphoproteome Analysis of the Plasma Membrane of Mouse Liver

(2008) Feng Tan et al.   JOURNAL OF PROTEOME RESEARCH

Signaling networks assembled by oncogenic EGFR and c-Met

(2008) A. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE