Noonan, Costello and cardio–facio–cutaneous syndromes: dysregulation of the Ras–MAPK pathway

Noonan syndrome: coagulation and clinical aspects

(2010) AA Massarano et al.   ACTA PAEDIATRICA

The diagnosis of Costello syndrome: Nomenclature in Ras/MAPK pathway disorders

(2008) Bronwyn Kerr et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Costello syndrome associated with novel germlineHRAS mutations: An attenuated phenotype?

(2008) Karen W. Gripp et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Advances in the Development of Cancer Therapeutics Directed against the RAS-Mitogen-Activated Protein Kinase Pathway

(2008) J. S. Sebolt-Leopold   CLINICAL CANCER RESEARCH

Diverse driving forces underlie the invariant occurrence of the T42A, E139D, I282V and T468M SHP2 amino acid substitutions causing Noonan and LEOPARD syndromes

(2008) Simone Martinelli et al.   HUMAN MOLECULAR GENETICS

Isolation of a distinct class of gain-of-function SHP-2 mutants with oncogenic RAS-like transforming activity from solid tumors

(2008) D Miyamoto et al.   ONCOGENE

Hepatoblastoma in a Noonan syndrome patient with aPTPN11 mutation

(2008) Rie Yoshida et al.   PEDIATRIC BLOOD & CANCER

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

(2008) J. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SOS1 mutations are rare in human malignancies: Implications for Noonan syndrome patients

(2007) Kenneth D. Swanson et al.   GENES CHROMOSOMES & CANCER

Mutation analysis in Costello syndrome: functional and structural characterization of theHRASp.Lys117Arg mutation

(2007) Ellen Denayer et al.   HUMAN MUTATION