Downregulation of PHLPP Expression Contributes to Hypoxia-Induced Resistance to Chemotherapy in Colon Cancer Cells
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Title
Downregulation of PHLPP Expression Contributes to Hypoxia-Induced Resistance to Chemotherapy in Colon Cancer Cells
Authors
Keywords
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Journal
MOLECULAR AND CELLULAR BIOLOGY
Volume 33, Issue 22, Pages 4594-4605
Publisher
American Society for Microbiology
Online
2013-09-24
DOI
10.1128/mcb.00695-13
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Note: Only part of the references are listed.- A unifying model for mTORC1-mediated regulation of mRNA translation
- (2012) Carson C. Thoreen et al. NATURE
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- (2011) Noel A. Warfel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Suppression of dual-specificity phosphatase–2 by hypoxia increases chemoresistance and malignancy in human cancer cells
- (2011) Shih-Chieh Lin et al. JOURNAL OF CLINICAL INVESTIGATION
- PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma
- (2011) J R Molina et al. ONCOGENE
- Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells
- (2011) T. M. Yeung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIF1A Overexpression Is Associated with Poor Prognosis in a Cohort of 731 Colorectal Cancers
- (2010) Yoshifumi Baba et al. AMERICAN JOURNAL OF PATHOLOGY
- Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis
- (2010) X. Lu et al. CLINICAL CANCER RESEARCH
- Tuberous Sclerosis Complex 2 (TSC2) Regulates Cell Migration and Polarity through Activation of CDC42 and RAC1
- (2010) Yan Larson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- mTOR-Dependent Regulation of PHLPP Expression Controls the Rapamycin Sensitivity in Cancer Cells
- (2010) Jianyu Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mst1 Is an Interacting Protein that Mediates PHLPPs' Induced Apoptosis
- (2010) Meng Qiao et al. MOLECULAR CELL
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- A Molecular Link between AKT Regulation and Chemotherapeutic Response
- (2009) Christian C. Dibble et al. CANCER CELL
- FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt
- (2009) Huadong Pei et al. CANCER CELL
- -TrCP-Mediated Ubiquitination and Degradation of PHLPP1 Are Negatively Regulated by Akt
- (2009) X. Li et al. MOLECULAR AND CELLULAR BIOLOGY
- SCOP/PHLPP and its functional role in the brain
- (2009) Kimiko Shimizu et al. Molecular BioSystems
- Molecular mechanisms of mTOR-mediated translational control
- (2009) Xiaoju Max Ma et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Redox mechanisms switch on hypoxia-dependent epithelial–mesenchymal transition in cancer cells
- (2008) Stefania Cannito et al. CARCINOGENESIS
- The role of hypoxia-inducible factors in tumorigenesis
- (2008) E B Rankin et al. CELL DEATH AND DIFFERENTIATION
- Hypoxia regulates TSC1/2 mTOR signaling and tumor suppression through REDD1-mediated 14 3 3 shuttling
- (2008) M. P. DeYoung et al. GENES & DEVELOPMENT
- HIF-1α and HIF-2α have divergent roles in colon cancer
- (2008) Takaaki Imamura et al. INTERNATIONAL JOURNAL OF CANCER
- Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis
- (2008) J Liu et al. ONCOGENE
- PHLiPPing the switch on Akt and protein kinase C signaling
- (2008) John Brognard et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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