Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase (PHLPP): A New Player in Cell Signaling
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Title
Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase (PHLPP): A New Player in Cell Signaling
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 6, Pages 3610-3616
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2011-12-06
DOI
10.1074/jbc.r111.318675
References
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Related references
Note: Only part of the references are listed.- Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression
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- (2011) F. Andreozzi et al. DIABETOLOGIA
- Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt
- (2011) Xin Li et al. EMBO REPORTS
- Mislocalization of the E3 Ligase, β-Transducin Repeat-containing Protein 1 (β-TrCP1), in Glioblastoma Uncouples Negative Feedback between the Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase 1 (PHLPP1) and Akt
- (2011) Noel A. Warfel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: PHLPP Regulates the Development, Function, and Molecular Signaling Pathways of Regulatory T Cells
- (2011) S. J. Patterson et al. JOURNAL OF IMMUNOLOGY
- PHLPP-Mediated Dephosphorylation of S6K1 Inhibits Protein Translation and Cell Growth
- (2011) J. Liu et al. MOLECULAR AND CELLULAR BIOLOGY
- PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma
- (2011) J R Molina et al. ONCOGENE
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- PHLPP-1 Negatively Regulates Akt Activity and Survival in the Heart
- (2010) Shigeki Miyamoto et al. CIRCULATION RESEARCH
- mTOR-Dependent Regulation of PHLPP Expression Controls the Rapamycin Sensitivity in Cancer Cells
- (2010) Jianyu Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of Small Molecule Inhibitors of the PH Domain Leucine-Rich Repeat Protein Phosphatase (PHLPP) by Chemical and Virtual Screening
- (2010) Emma Sierecki et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mst1 Is an Interacting Protein that Mediates PHLPPs' Induced Apoptosis
- (2010) Meng Qiao et al. MOLECULAR CELL
- Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
- (2010) Shomit Sengupta et al. MOLECULAR CELL
- Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock
- (2010) S. Masubuchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt
- (2009) Huadong Pei et al. CANCER CELL
- Serine/Threonine Phosphatases: Mechanism through Structure
- (2009) Yigong Shi CELL
- Common Polymorphism in the Phosphatase PHLPP2 Results in Reduced Regulation of Akt and Protein Kinase C
- (2009) John Brognard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- -TrCP-Mediated Ubiquitination and Degradation of PHLPP1 Are Negatively Regulated by Akt
- (2009) X. Li et al. MOLECULAR AND CELLULAR BIOLOGY
- The nuts and bolts of AGC protein kinases
- (2009) Laura R. Pearce et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients
- (2008) D. Cozzone et al. DIABETOLOGIA
- Comprehensive Identification of PIP3-Regulated PH Domains from C. elegans to H. sapiens by Model Prediction and Live Imaging
- (2008) Wei Sun Park et al. MOLECULAR CELL
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis
- (2008) J Liu et al. ONCOGENE
- PHLiPPing the switch on Akt and protein kinase C signaling
- (2008) John Brognard et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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