The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer
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Title
The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer
Authors
Keywords
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Journal
ONCOGENE
Volume 32, Issue 4, Pages 471-478
Publisher
Springer Nature
Online
2012-03-06
DOI
10.1038/onc.2012.66
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- (2011) Noel A. Warfel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma
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- (2009) X. Li et al. MOLECULAR AND CELLULAR BIOLOGY
- SCOP/PHLPP and its functional role in the brain
- (2009) Kimiko Shimizu et al. Molecular BioSystems
- Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
- (2009) Martin Schwickart et al. NATURE
- Breaking the chains: structure and function of the deubiquitinases
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- The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation
- (2009) W.-L. Yang et al. SCIENCE
- Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis
- (2008) J Liu et al. ONCOGENE
- PHLiPPing the switch on Akt and protein kinase C signaling
- (2008) John Brognard et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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