Copper binding modulates the platination of human copper chaperone Atox1 by antitumor trans-platinum complexes

Transporting platinum drugs from a copper chaperone to ATPase: the mechanistic implication of drug efflux mediated cisplatin resistance

(2014) Dechen Xu et al.   Inorganic Chemistry Frontiers

Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification

(2013) Nataliya V. Dolgova et al.   BIOCHEMICAL JOURNAL

Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1

(2013) Zhaoyong Xi et al.   CHEMICAL COMMUNICATIONS

An Updated View of Cisplatin Transport

(2013) Fabio Arnesano et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Interaction of cisplatin and analogue Pt(en)Cl2 with the copper metallo-chaperone Atox1

(2013) Chak Ming Sze et al.   Metallomics

Conserved residue modulates copper-binding properties through structural dynamics in human copper chaperone Atox1

(2013) Zhaoyong Xi et al.   Metallomics

PtCl2(phen) disrupts the metal ions binding to amyloid-β peptide

(2013) Guolin Ma et al.   Metallomics

Determinants for Simultaneous Binding of Copper and Platinum to Human Chaperone Atox1: Hitchhiking not Hijacking

(2013) Maria E. Palm-Espling et al.   PLoS One

Interactions of anticancer Pt compounds with proteins: an overlooked topic in medicinal inorganic chemistry?

(2012) Angela Casini et al.   Chemical Science

Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7BThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.

(2011) Oleg Y. Dmitriev   Biochemistry and Cell Biology

Distorted copper homeostasis with decreased sensitivity to cisplatin upon chaperone Atox1 deletion in Drosophila

(2011) Haiqing Hua et al.   BIOMETALS

The anticancer drug cisplatin can cross-link the interdomain zinc site on human albumin

(2011) Wenbing Hu et al.   CHEMICAL COMMUNICATIONS

Probing the Interaction of Cisplatin with the Human Copper Chaperone Atox1 by Solution and In-Cell NMR Spectroscopy

(2011) Fabio Arnesano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro

(2011) M. E. Palm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs

(2010) S. B. Howell et al.   MOLECULAR PHARMACOLOGY

Methionine Can Favor DNA Platination bytrans-Coordinated Platinum Antitumor Drugs

(2009) Chan Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The soluble metal-binding domain of the copper transporter ATP7B binds and detoxifies cisplatin

(2009) Nataliya V. Dolgova et al.   BIOCHEMICAL JOURNAL

Structural Biology of Copper Trafficking

(2009) Amie K. Boal et al.   CHEMICAL REVIEWS

Towards Antitumor Activetrans-Platinum Compounds

(2009) Sheena M. Aris et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Crystal Structures of Cisplatin Bound to a Human Copper Chaperone

(2009) Amie K. Boal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effects of the loss of Atox1 on the cellular pharmacology of cisplatin

(2008) Roohangiz Safaei et al.   JOURNAL OF INORGANIC BIOCHEMISTRY