PtCl2(phen) disrupts the metal ions binding to amyloid-β peptide

Pt(ii) compounds interplay with Cu(ii) and Zn(ii) coordination to the amyloid-β peptide has metal specific consequences on deleterious processes associated to Alzheimer's disease

(2013) Fabrice Collin et al.   CHEMICAL COMMUNICATIONS

Therapeutic Redistribution of Metal Ions To Treat Alzheimer’s Disease

(2012) Peter J. Crouch et al.   ACCOUNTS OF CHEMICAL RESEARCH

Trans-Platinum/Thiazole Complex Interferes with Sp1 Zinc-Finger Protein

(2012) Siming Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

(2012) I. W. Hamley   CHEMICAL REVIEWS

Bioinorganic Chemistry of Alzheimer’s Disease

(2012) Kasper P. Kepp   CHEMICAL REVIEWS

Protein Misfolded Oligomers: Experimental Approaches, Mechanism of Formation, and Structure-Toxicity Relationships

(2012) Francesco Bemporad et al.   CHEMISTRY & BIOLOGY

Metal ions and amyloid fiber formation in neurodegenerative diseases. Copper, zinc and iron in Alzheimer's, Parkinson's and prion diseases

(2012) John H. Viles   COORDINATION CHEMISTRY REVIEWS

Metal compounds as inhibitors of β-amyloid aggregation. Perspectives for an innovative metallotherapeutics on Alzheimer's disease

(2012) Daniela Valensin et al.   COORDINATION CHEMISTRY REVIEWS

Interference of a new cyclometallated Pt compound with Cu binding to amyloid-β peptide

(2012) Isabelle Sasaki et al.   DALTON TRANSACTIONS

Inhibitory action of macrocyclic platiniferous chelators on metal-induced Aβ aggregation

(2012) Xiaohui Wang et al.   Chemical Science

The β-Amyloid Hypothesis in Alzheimer's Disease: Seeing Is Believing

(2012) Hank F. Kung   ACS Medicinal Chemistry Letters

The Heterogeneous Nature of Cu2+Interactions with Alzheimer’s Amyloid-β Peptide

(2011) Simon C. Drew et al.   ACCOUNTS OF CHEMICAL RESEARCH

Identification of [PtCl2(phen)] Binding Modes in Amyloid-β Peptide and the Mechanism of Aggregation Inhibition

(2011) Guolin Ma et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structural characterization of Cu2+, Ni2+ and Zn2+ binding sites of model peptides associated with neurodegenerative diseases

(2011) Caterina Migliorini et al.   COORDINATION CHEMISTRY REVIEWS

Coordination of zinc ions to the key proteins of neurodegenerative diseases: Aβ, APP, α-synuclein and PrP

(2011) Vello Tõugu et al.   COORDINATION CHEMISTRY REVIEWS

pH-Dependent Cu(II) Coordination to Amyloid-β Peptide: Impact of Sequence Alterations, Including the H6R and D7N Familial Mutations.

(2011) Bruno Alies et al.   INORGANIC CHEMISTRY

Distinct Effects of Zn2+, Cu2+, Fe3+, and Al3+on Amyloid-β Stability, Oligomerization, and Aggregation

(2011) Wei-Ting Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of metallobiology and amyloid-β peptides in Alzheimer’s disease

(2011) Blaine R. Roberts et al.   JOURNAL OF NEUROCHEMISTRY

Group 9 metal-based inhibitors of β-amyloid (1–40) fibrillation as potential therapeutic agents for Alzheimer's disease

(2011) Bradley Yat-Wah Man et al.   Chemical Science

Inhibition of Aβ42 Peptide Aggregation by a Binuclear Ruthenium(II)−Platinum(II) Complex: Potential for Multimetal Organometallics as Anti-amyloid Agents

(2010) Amit Kumar et al.   ACS Chemical Neuroscience

Copper(II) Coordination to Amyloid β: Murine versus Human Peptide

(2010) Hélène Eury et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alzheimer's Aβ Peptides with Disease-Associated N-Terminal Modifications: Influence of Isomerisation, Truncation and Mutation on Cu2+ Coordination

(2010) Simon C. Drew et al.   PLoS One

Zinc ions promote Alzheimer A  aggregation via population shift of polymorphic states

(2010) Y. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of small molecules that target metal-A  species and regulate metal-induced A  aggregation and neurotoxicity

(2010) J.-S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deprotonation of the Asp1Ala2 Peptide Bond Induces Modification of the Dynamic Copper(II) Environment in the Amyloid-β Peptide near Physiological pH

(2009) Christelle Hureau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alzheimer's Disease: From Pathology to Therapeutic Approaches

(2009) Roland Jakob-Roetne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pulse EPR Spectroscopy Reveals the Coordination Sphere of Copper(II) Ions in the 1–16 Amyloid-β Peptide: A Key Role of the First Two N-Terminus Residues

(2009) Pierre Dorlet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper and Zinc Binding to Amyloid-β: Coordination, Dynamics, Aggregation, Reactivity and Metal-Ion Transfer

(2009) Peter Faller   CHEMBIOCHEM

Risks of Copper and Iron Toxicity during Aging in Humans

(2009) George J. Brewer   CHEMICAL RESEARCH IN TOXICOLOGY

Pleomorphic Copper Coordination by Alzheimer’s Disease Amyloid-β Peptide

(2009) Simon C. Drew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alzheimer's disease, metal ions and metal homeostatic therapy

(2009) Paolo Zatta et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide

(2008) Peter Faller et al.   DALTON TRANSACTIONS

Platinum-based inhibitors of amyloid-  as therapeutic agents for Alzheimer's disease

(2008) K. J. Barnham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA