4.7 Article

Bringing DNA Repair in Tumors into Focus

Journal

CLINICAL CANCER RESEARCH
Volume 15, Issue 10, Pages 3241-3243

Publisher

AMER ASSOC CANCER RESEARCH
DOI: 10.1158/1078-0432.CCR-09-0434

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Funding

  1. Breast Cancer Now [BREAST CANCER NOW RESEARCH CENTRE] Funding Source: Medline

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Biomarkers are of crucial importance in optimizing cancer therapies. In this edition of Clinical Cancer Research, Banuelos and colleagues assess H2AX phosphorylation as a predictive biomarker of response to DNA damaging agents. We discuss these results as well as the impact that double strand break repair biomarkers may have in cancer therapy.

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