Role of cysteine 288 in nucleophosmin cytoplasmic mutations: sensitization to toxicity induced by arsenic trioxide and bortezomib

NADPH oxidase-produced superoxide mediates EGFR transactivation by c-Src in arsenic trioxide-stimulated human keratinocytes

(2012) Hong-Yu Tseng et al.   ARCHIVES OF TOXICOLOGY

Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia

(2012) P. Ranganathan et al.   BLOOD

Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells

(2012) Denis Selimovic et al.   CELLULAR SIGNALLING

Intrinsic and extrinsic negative regulators of nuclear protein transport processes

(2012) Toshihiro Sekimoto et al.   GENES TO CELLS

Regulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers

(2011) Yao E. Wang et al.   BIOLOGY OF THE CELL

Do reactive oxygen species play a role in myeloid leukemias?

(2011) P. S. Hole et al.   BLOOD

Acute myeloid leukemia with mutated nucleophosmin (NPM1): Any hope for a targeted therapy?

(2011) Brunangelo Falini et al.   BLOOD REVIEWS

Phase 1 study of arsenic trioxide, high-dose cytarabine, and idarubicin to down-regulate constitutive signal transducer and activator of transcription 3 activity in patients aged

(2011) Meir Wetzler et al.   CANCER

Bortezomib induces autophagy in head and neck squamous cell carcinoma cells via JNK activation

(2011) Changyou Li et al.   CANCER LETTERS

Bortezomib Primes Neuroblastoma Cells for TRAIL-Induced Apoptosis by Linking the Death Receptor to the Mitochondrial Pathway

(2011) I. Naumann et al.   CLINICAL CANCER RESEARCH

Arsenic-induced oxidative stress and its reversibility

(2011) Swaran J.S. Flora   FREE RADICAL BIOLOGY AND MEDICINE

Reactive Oxygen Species Regulate Nucleostemin Oligomerization and Protein Degradation

(2011) Min Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bortezomib stabilizes NOXA and triggers ROS-associated apoptosis in medulloblastoma

(2011) Sachiko Ohshima-Hosoyama et al.   JOURNAL OF NEURO-ONCOLOGY

Impact of arsenic trioxide in the treatment of acute promyelocytic leukemia

(2011) E Lengfelder et al.   LEUKEMIA

Mechanism of Action of Proteasome Inhibitors and Deacetylase Inhibitors and the Biological Basis of Synergy in Multiple Myeloma

(2011) T. Hideshima et al.   MOLECULAR CANCER THERAPEUTICS

Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases

(2011) E Colombo et al.   ONCOGENE

Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells

(2010) N. B. Heaney et al.   BLOOD

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

(2010) B. Falini et al.   BLOOD

The Tale of Protein Lysine Acetylation in the Cytoplasm

(2010) Karin Sadoul et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Biological Responses to Arsenic Compounds

(2009) Leonidas C. Platanias   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternatively Spliced Isoforms of TRIP8b Differentially Control h Channel Trafficking and Function

(2009) A. S. Lewis et al.   JOURNAL OF NEUROSCIENCE

Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells

(2009) K Zhu et al.   ONCOGENE

Oxidative Stress by Targeted Agents Promotes Cytotoxicity in Hematologic Malignancies

(2008) Joya Chandra   ANTIOXIDANTS & REDOX SIGNALING

Arsenic trioxide and low-dose cytarabine in older patients with untreated acute myeloid leukemia, excluding acute promyelocytic leukemia

(2008) Gail J. Roboz et al.   CANCER

The therapeutic potential of the proteasome in leukaemia

(2008) Scott Marshall McCloskey et al.   HEMATOLOGICAL ONCOLOGY

Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia

(2008) Charles G. Grummitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway

(2008) M. Lioni et al.   MOLECULAR CANCER THERAPEUTICS

NADPH oxidase-derived reactive oxygen species are responsible for the high susceptibility to arsenic cytotoxicity in acute promyelocytic leukemia cells

(2007) Jie Wang et al.   LEUKEMIA RESEARCH