Regulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers

The Drosophila STUbL protein Degringolade limits HES functions during embryogenesis

(2011) K. C. Barry et al.   DEVELOPMENT

Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression

(2011) Mona Abed et al.   EMBO JOURNAL

Ran-dependent nuclear export mediators: a structural perspective

(2011) Thomas Güttler et al.   EMBO JOURNAL

A fly view of a SUMO-targeted ubiquitin ligase

(2011) Mona Abed et al.   FLY

Viral Takeover of the Host Ubiquitin System

(2011) Jean K. Gustin et al.   Frontiers in Microbiology

SUMO and ubiquitin paths converge

(2010) Amanda Denuc et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome

(2010) Y. Kfoury et al.   BLOOD

Evaluation of the Proteasome Inhibitor MLN9708 in Preclinical Models of Human Cancer

(2010) E. Kupperman et al.   CANCER RESEARCH

USP10 Regulates p53 Localization and Stability by Deubiquitinating p53

(2010) Jian Yuan et al.   CELL

Building on bortezomib: second-generation proteasome inhibitors as anti-cancer therapy

(2010) Lawrence R. Dick et al.   DRUG DISCOVERY TODAY

The SUMO protease SENP6 is essential for inner kinetochore assembly

(2010) Debaditya Mukhopadhyay et al.   JOURNAL OF CELL BIOLOGY

HTLV-1 and Adult T-Cell Leukemia: Insights into Viral Transformation of Cells 30 Years After Virus Discovery

(2010) Kuan-Teh Jeang   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Epstein-Barr Virus LF2 Protein Regulates Viral Replication by Altering Rta Subcellular Localization

(2010) A. M. F. Heilmann et al.   JOURNAL OF VIROLOGY

The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle

(2010) M. Raaben et al.   JOURNAL OF VIROLOGY

The Clinically Approved Proteasome Inhibitor PS-341 Efficiently Blocks Influenza A Virus and Vesicular Stomatitis Virus Propagation by Establishing an Antiviral State

(2010) S. E. Dudek et al.   JOURNAL OF VIROLOGY

Proteasome Inhibition In Vivo Promotes Survival in a Lethal Murine Model of Severe Acute Respiratory Syndrome

(2010) X.-Z. Ma et al.   JOURNAL OF VIROLOGY

Sumoylation of the Epstein-Barr Virus BZLF1 Protein Inhibits Its Transcriptional Activity and Is Regulated by the Virus-Encoded Protein Kinase

(2010) S. R. Hagemeier et al.   JOURNAL OF VIROLOGY

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy

(2010) M Matsuoka et al.   ONCOGENE

Ubiquitin/SUMO Modification Regulates VHL Protein Stability and Nucleocytoplasmic Localization

(2010) Qiliang Cai et al.   PLoS One

SUMOylation Mediates the Nuclear Translocation and Signaling of the IGF-1 Receptor

(2010) B. Sehat et al.   Science Signaling

Multitasking with ubiquitin through multivalent interactions

(2010) Fen Liu et al.   TRENDS IN BIOCHEMICAL SCIENCES

NF-κB signaling modulation by EBV and KSHV

(2010) Deilson Elgui de Oliveira et al.   TRENDS IN MICROBIOLOGY

Ubiquitin-Regulated Nuclear-Cytoplasmic Trafficking of the Nipah Virus Matrix Protein Is Important for Viral Budding

(2010) Yao E. Wang et al.   PLoS Pathogens

Bortezomib Inhibits Hepatitis B Virus Replication in Transgenic Mice

(2009) P. Bandi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Proteasome inhibitors block HIV-1 replication by affecting both cellular and viral targets

(2009) Liang Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The multiple levels of regulation by p53 ubiquitination

(2009) J T Lee et al.   CELL DEATH AND DIFFERENTIATION

Regulation of p53 family members by the ubiquitin-like SUMO system

(2009) Per Stehmeier et al.   DNA REPAIR

Small Ubiquitin-Like Modifier-2 Modification of Retinoic Acid Receptor-α Regulates Its Subcellular Localization and Transcriptional Activity

(2009) Li Zhu et al.   ENDOCRINOLOGY

No strings attached: the ESCRT machinery in viral budding and cytokinesis

(2009) B. McDonald et al.   JOURNAL OF CELL SCIENCE

Paramyxovirus Disruption of Interferon Signal Transduction: STATus Report

(2009) Aparna Ramachandran et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Regulation of Type I Interferon Production by Paramyxoviruses

(2009) Stephen Goodbourn et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)

(2009) Han-Jie Zhou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Epstein-Barr Virus Nuclear Antigen 3C Augments Mdm2-Mediated p53 Ubiquitination and Degradation by Deubiquitinating Mdm2

(2009) A. Saha et al.   JOURNAL OF VIROLOGY

Masking of a Nuclear Signal Motif by Monoubiquitination Leads to Mislocalization and Degradation of the Regulatory Enzyme Cytidylyltransferase

(2009) B. B. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

An additional role for SUMO in ubiquitin-mediated proteolysis

(2009) Marie-Claude Geoffroy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-κB pathway

(2009) Julie Lodewick et al.   VIROLOGY

Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9

(2009) Amélie Fradet-Turcotte et al.   VIROLOGY

Sumoylation of Smad3 stimulates its nuclear export during PIASy-mediated suppression of TGF-β signaling

(2008) Seiyu Imoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SUMOylation Regulates Nuclear Localization of Krüppel-like Factor 5

(2008) James X. Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhancement of Transactivation Activity of Rta of Epstein-Barr Virus by RanBPM

(2008) Li-Kwan Chang et al.   JOURNAL OF MOLECULAR BIOLOGY

The Epstein-Barr Virus LF2 Protein Inhibits Viral Replication

(2008) M. A. Calderwood et al.   JOURNAL OF VIROLOGY

Orthopoxviruses Require a Functional Ubiquitin-Proteasome System for Productive Replication

(2008) A. Teale et al.   JOURNAL OF VIROLOGY

PPEY Motif within the Rabies Virus (RV) Matrix Protein Is Essential for Efficient Virion Release and RV Pathogenicity

(2008) C. Wirblich et al.   JOURNAL OF VIROLOGY

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

(2008) Min Sup Song et al.   NATURE

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

Different Effect of Proteasome Inhibition on Vesicular Stomatitis Virus and Poliovirus Replication

(2008) Nickolay Neznanov et al.   PLoS One

Identification of a nuclear export signal sequence for bovine papillomavirus E1 protein

(2008) Germán Rosas-Acosta et al.   VIROLOGY

Mechanisms for enveloped virus budding: Can some viruses do without an ESCRT?

(2007) Benjamin J. Chen et al.   VIROLOGY