Oncolytic (replication-competent) adenoviruses as anticancer agents

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

(2009) R. Alba et al.   BLOOD

New pancreatic carcinoma model for studying oncolytic adenoviruses in the permissive Syrian hamster

(2009) J F Spencer et al.   CANCER GENE THERAPY

INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies

(2009) B Ying et al.   CANCER GENE THERAPY

An acute toxicology study with INGN 007, an oncolytic adenovirus vector, in mice and permissive Syrian hamsters; comparisons with wild-type Ad5 and a replication-defective adenovirus vector

(2009) D L Lichtenstein et al.   CANCER GENE THERAPY

Telomeres and disease

(2009) Peter M Lansdorp   EMBO JOURNAL

Chemical Modification with High Molecular Weight Polyethylene Glycol Reduces Transduction of Hepatocytes and Increases Efficacy of Intravenously Delivered Oncolytic Adenovirus

(2009) Konstantin Doronin et al.   HUMAN GENE THERAPY

In vitroevaluation of a ‘stealth’ adenoviral vector for targeted gene delivery to adult mammalian neurones

(2009) Karen Sims et al.   JOURNAL OF GENE MEDICINE

Targeting the Intratumoral Dendritic Cells by the Oncolytic Adenoviral Vaccine Expressing RANTES Elicits Potent Antitumor Immunity

(2009) Natalia Lapteva et al.   JOURNAL OF IMMUNOTHERAPY

Targeting of Adenovirus Serotype 5 Pseudotyped with Short Fiber from Serotype 41 to c-erbB2-Positive Cells using Bispecific Single-Chain Diabody

(2009) Elena A. Kashentseva et al.   JOURNAL OF MOLECULAR BIOLOGY

Adenovirus E1B 55-Kilodalton Protein: Multiple Roles in Viral Infection and Cell Transformation

(2009) A. N. Blackford et al.   JOURNAL OF VIROLOGY

Pre-existing Immunity and Passive Immunity to Adenovirus 5 Prevents Toxicity Caused by an Oncolytic Adenovirus Vector in the Syrian Hamster Model

(2009) Debanjan Dhar et al.   MOLECULAR THERAPY

Ephrin A2 receptor targeting does not increase adenoviral pancreatic cancer transduction in vivo

(2009) Michael A van Geer et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Use of Tissue-Specific MicroRNA to Control Pathology of Wild-Type Adenovirus without Attenuation of Its Ability to Kill Cancer Cells

(2009) Ryan Cawood et al.   PLoS Pathogens

Immune Therapy for Cancer

(2008) Michael Dougan et al.   Annual Review of Immunology

An oncolytic adenovirus expressing granulocyte macrophage colony-stimulating factor shows improved specificity and efficacy for treating human solid tumors

(2008) N Lei et al.   CANCER GENE THERAPY

Biodistribution of an oncolytic adenovirus after intracranial injection in permissive animals: a comparative study of Syrian hamsters and cotton rats

(2008) A M Sonabend et al.   CANCER GENE THERAPY

Bioselection of a Gain of Function Mutation that Enhances Adenovirus 5 Release and Improves Its Antitumoral Potency

(2008) Alena Gros et al.   CANCER RESEARCH

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

(2008) Simon N. Waddington et al.   CELL

A Fiber-Modified Mesothelin Promoter-Based Conditionally Replicating Adenovirus for Treatment of Ovarian Cancer

(2008) Y. Tsuruta et al.   CLINICAL CANCER RESEARCH

Significant antitumor activity of oncolytic adenovirus expressing human interferon-β for hepatocellular carcinoma

(2008) Ling Feng He et al.   JOURNAL OF GENE MEDICINE

A ligand-pseudoreceptor system based onde novo designed peptides for the generation of adenoviral vectors with altered tropism

(2008) Yue Zeng et al.   JOURNAL OF GENE MEDICINE

Adenoviruses: update on structure and function

(2008) W. C. Russell   JOURNAL OF GENERAL VIROLOGY

Effect of Preexisting Immunity on Oncolytic Adenovirus Vector INGN 007 Antitumor Efficacy in Immunocompetent and Immunosuppressed Syrian Hamsters

(2008) D. Dhar et al.   JOURNAL OF VIROLOGY

Generation of a Conditionally Replicating Adenovirus Based on Targeted Destruction of E1A mRNA by a Cell Type-Specific MicroRNA

(2008) E. Ylosmaki et al.   JOURNAL OF VIROLOGY

Intrinsic Structural Disorder in Adenovirus E1A: a Viral Molecular Hub Linking Multiple Diverse Processes

(2008) P. Pelka et al.   JOURNAL OF VIROLOGY

Modification of Adenoviral Vectors With Polyethylene Glycol Modulates In Vivo Tissue Tropism and Gene Expression

(2008) Sean E Hofherr et al.   MOLECULAR THERAPY

Immunosuppression Enhances Oncolytic Adenovirus Replication and Antitumor Efficacy in the Syrian Hamster Model

(2008) Maria A Thomas et al.   MOLECULAR THERAPY

Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded

(2008) Roberto Cattaneo et al.   NATURE REVIEWS MICROBIOLOGY

The tumour microenvironment: a novel target for cancer therapy

(2008) E Hanna et al.   ORAL DISEASES

Directed Evolution Generates a Novel Oncolytic Virus for the Treatment of Colon Cancer

(2008) Irene Kuhn et al.   PLoS One

Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model

(2008) K. Toth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo

(2008) O. Kalyuzhniy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidermal growth factor (EGF) receptor targeted delivery of PEGylated adenovirus

(2007) Ji Won Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Development of PEGylated adenovirus vector with targeting ligand

(2007) Yusuke Eto et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Modification of Adenovirus Gene Transfer Vectors With Synthetic Polymers: A Scientific Review and Technical Guide

(2007) Florian Kreppel et al.   MOLECULAR THERAPY

Adenovirus vector induced innate immune responses: Impact upon efficacy and toxicity in gene therapy and vaccine applications

(2007) Zachary C. Hartman et al.   VIRUS RESEARCH