Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
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Title
Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 113, Issue 1, Pages 26-33
Publisher
Proceedings of the National Academy of Sciences
Online
2015-12-15
DOI
10.1073/pnas.1522364112
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- (2014) Micah J. Niphakis et al. Annual Review of Biochemistry
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- (2014) Rebecca A. Kohnz et al. CHEMICAL SOCIETY REVIEWS
- The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase
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