The Obesogen Hypothesis: A Shift of Focus from the Periphery to the Hypothalamus

Neuroendocrine targets of endocrine disruptors

(2014) Andrea Gore   Hormones-International Journal of Endocrinology and Metabolism

Environmental chemicals and thyroid function: an update

(2011) Malene Boas et al.   Current Opinion in Endocrinology Diabetes and Obesity

Obesogens

(2011) Felix Grün   Current Opinion in Endocrinology Diabetes and Obesity

Tributyltin-induced imposex in marine gastropods involves tissue-specific modulation of the retinoid X receptor

(2010) D. Lima et al.   AQUATIC TOXICOLOGY

Screening chemicals for thyroid-disrupting activity: A critical comparison of mammalian and amphibian models

(2010) Daniel B. Pickford   CRITICAL REVIEWS IN TOXICOLOGY

Organotin intake through fish consumption in Finland

(2010) Riikka Airaksinen et al.   ENVIRONMENTAL RESEARCH

C-fin: A cultured frog tadpole tail fin biopsy approach for detection of thyroid hormone-disrupting chemicals

(2010) Ashley Hinther et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Regulation of the hypothalamic Thyrotropin Releasing Hormone (TRH) neuron by neuronal and peripheral inputs

(2010) Eduardo A. Nillni   FRONTIERS IN NEUROENDOCRINOLOGY

Association of endocrine disruptors and obesity: perspectives from epidemiological studies

(2010) E. E. Hatch et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

A Rapid Interference between Glucocorticoids and cAMP-Activated Signalling in Hypothalamic Neurones Prevents Binding of Phosphorylated cAMP Response Element Binding Protein and Glucocorticoid Receptor at the CRE-Like and Composite GRE Sites of Thyrotrophin-Releasing Hormone Gene Promoter

(2010) M. Y. Díaz-Gallardo et al.   JOURNAL OF NEUROENDOCRINOLOGY

Role of Early Hormonal and Nutritional Experiences in Shaping Feeding Behavior and Hypothalamic Development

(2010) Sebastien G. Bouret   JOURNAL OF NUTRITION

The Potential of Selected Brominated Flame Retardants to Affect Neurological Development

(2010) Amy Lavin Williams et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Metabolic and melanocortin gene expression alterations in male offspring of obese mice

(2010) Johann Gout et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Disruption of thyroid hormone-dependent hypothalamic set-points by environmental contaminants

(2010) Stéphanie Decherf et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Prenatal Exposure to the Environmental Obesogen Tributyltin Predisposes Multipotent Stem Cells to Become Adipocytes

(2010) Séverine Kirchner et al.   MOLECULAR ENDOCRINOLOGY

Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression

(2010) S. Decherf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-concentration tributyltin perturbs inhibitory synaptogenesis and induces neuronal death in immature but not mature neurons

(2010) Junko Yamada et al.   TOXICOLOGY LETTERS

Development of analytical procedures for trace-level determination of polybrominated diphenyl ethers and tetrabromobisphenol A in river water and sediment

(2009) Pierre Labadie et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

DNA hypomethylation induced by tributyltin, triphenyltin, and a mixture of these in Sebastiscus marmoratus liver

(2009) Yuqing Wang et al.   AQUATIC TOXICOLOGY

Endocrine disruptors and thyroid hormone physiology

(2009) Mary-Line Jugan et al.   BIOCHEMICAL PHARMACOLOGY

T3 differentially regulates TRH expression in developing hypothalamic neurons in vitro

(2009) Alfonso Carreón-Rodríguez et al.   BRAIN RESEARCH

Imposex and organotin prevalence in a European post-legislative scenario: Temporal trends from 2003 to 2008

(2009) Ana Sousa et al.   CHEMOSPHERE

Environmental-endocrine control of reproductive maturation in gastropods: implications for the mechanism of tributyltin-induced imposex in prosobranchs

(2009) Robin M. Sternberg et al.   ECOTOXICOLOGY

Activation of RXR–PPAR heterodimers by organotin environmental endocrine disruptors

(2009) Albane le Maire et al.   EMBO REPORTS

Perinatal Exposure to Brominated Flame Retardants and Polychlorinated Biphenyls in Japan

(2009) Yukiko KAWASHIRO et al.   ENDOCRINE JOURNAL

The Thyrotropin-Releasing Hormone Gene Is Regulated by Thyroid Hormone at the Level of Transcriptionin Vivo

(2009) Michelle L. Sugrue et al.   ENDOCRINOLOGY

Offspring of Women Exposed In Utero to Diethylstilbestrol (DES)

(2009) Linda Titus-Ernstoff et al.   EPIDEMIOLOGY

Hormone delivery systems to the brain - transthyretin

(2009) G. Schreiber et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Critical determinants of hypothalamic appetitive neuropeptide development and expression: Species considerations

(2009) B.E. Grayson et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Birth defects in the sons and daughters of women who were exposed in utero to diethylstilbestrol (DES)

(2009) L. Titus-Ernstoff et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Farnesoid X Receptor, through the Binding with Steroidogenic Factor 1-responsive Element, Inhibits Aromatase Expression in Tumor Leydig Cells

(2009) Stefania Catalano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neonatal overfeeding leads to developmental programming of adult obesity: you are what youate

(2009) L. J. Prior et al.   JOURNAL OF PHYSIOLOGY-LONDON

Baseline of butyltin pollution in coastal sediments within the Basque Country (northern Spain), in 2007–2008

(2009) J. Germán Rodríguez et al.   MARINE POLLUTION BULLETIN

Interpreting endocrine disruption from an integrative biology perspective

(2009) Ana M. Soto et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Special issue on the topic: Role of endocrine disruptors from the environment in the aetiology of obesity and diabetes

(2009) Michel L. Aubert et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Role of nutrition and environmental endocrine disrupting chemicals during the perinatal period on the aetiology of obesity☆

(2009) Jerrold J. Heindel et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Endocrine disrupters as obesogens

(2009) Felix Grün et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Peroxisome proliferator-activated receptor-γ (PPARγ) modulates hypothalamic Trh regulation in vivo

(2009) Soumaya Kouidhi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Thyroid hormone mimetics: potential applications in atherosclerosis, obesity and type 2 diabetes

(2009) John D. Baxter et al.   NATURE REVIEWS DRUG DISCOVERY

Environmental Endocrine Disruptors Promote Adipogenesis in the 3T3-L1 Cell Line through Glucocorticoid Receptor Activation

(2009) Robert M. Sargis et al.   Obesity

De-Novo Identification of PPARγ/RXR Binding Sites and Direct Targets during Adipogenesis

(2009) Mohamed Sabry Hamza et al.   PLoS One

Independent elaboration of steroid hormone signaling pathways in metazoans

(2009) G. V. Markov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental toxicity of brominated flame retardants, tetrabromobisphenol A and 1,2,5,6,9,10-hexabromocyclododecane, in rat offspring after maternal exposure from mid-gestation through lactation

(2009) Yukie Saegusa et al.   REPRODUCTIVE TOXICOLOGY

Brominated flame retardants in the Arctic environment — trends and new candidates

(2009) Cynthia A. de Wit et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Anti-thyroid hormone activity of bisphenol A, tetrabromobisphenol A and tetrachlorobisphenol A in an improved reporter gene assay

(2009) Hong Sun et al.   TOXICOLOGY IN VITRO

Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice

(2009) Akira Nakajima et al.   TOXICOLOGY LETTERS

Effects of plasticizers and their mixtures on estrogen receptor and thyroid hormone functions

(2009) Mandana Ghisari et al.   TOXICOLOGY LETTERS

Structure and physiological functions of the human peroxisome proliferator-activated receptor γ

(2008) Andrzej Zieleniak et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Molecular targets of TBBPA in zebrafish analysed through integration of genomic and proteomic approaches

(2008) Marijke De Wit et al.   CHEMOSPHERE

Exposure assessment of French women and their newborns to tetrabromobisphenol-A: Occurrence measurements in maternal adipose tissue, serum, breast milk and cord serum

(2008) Ronan Cariou et al.   CHEMOSPHERE

Leaching of brominated flame retardants from TV housing plastics in the presence of dissolved humic matter

(2008) Ki-In Choi et al.   CHEMOSPHERE

Synchronized Expression of Retinoid X Receptor mRNA with Reproductive Tract Recrudescence in an Imposex-Susceptible Mollusc

(2008) Robin M. Sternberg et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Prenatal exposure to diethylstilbestrol (DES)

(2008) Retha R. Newbold   FERTILITY AND STERILITY

Effects of endocrine disruptors on obesity

(2008) Retha R. Newbold et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Adeno-associated virus-mediated knockdown of melanocortin-4 receptor in the paraventricular nucleus of the hypothalamus promotes high-fat diet-induced hyperphagia and obesity

(2008) Jacob C Garza et al.   JOURNAL OF ENDOCRINOLOGY

Effects of Endocrine Disrupting Chemicals on Amphibian Metamorphosis and Mitochondrial Membrane Permeability Transition

(2008) Akihiko Kashiwagi et al.   JOURNAL OF HEALTH SCIENCE

Endocrine disruption induced by organotin compounds; organotins function as a powerful agonist for nuclear receptors rather than an aromatase inhibitor

(2008) Tsuyoshi Nakanishi   JOURNAL OF TOXICOLOGICAL SCIENCES

Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction

(2008) Jarl E. S. Wikberg et al.   NATURE REVIEWS DRUG DISCOVERY

The PKC and ERK/MAPK Pathways Regulate Glucocorticoid Action on TRH Transcription

(2008) Antonieta Cote-Vélez et al.   NEUROCHEMICAL RESEARCH

Dibutyltin Disrupts Glucocorticoid Receptor Function and Impairs Glucocorticoid-Induced Suppression of Cytokine Production

(2008) Christel Gumy et al.   PLoS One

Blood levels of organotin compounds and their relation to fish consumption in Finland

(2008) Panu Rantakokko et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The Role of the Thyrotropin-Releasing Hormone (TRH) Neuron as a Metabolic Sensor

(2008) Anthony N. Hollenberg   THYROID

Exposure to tetrabromobisphenol A (TBBPA) in Wistar rats: Neurobehavioral effects in offspring from a one-generation reproduction study

(2008) Hellmuth Lilienthal et al.   TOXICOLOGY

Biosensor discovery of thyroxine transport disrupting chemicals

(2008) Gerardo R. Marchesini et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tetrabromobisphenol A (TBBPA) and hexabromocyclododecanes (HBCDs) in tissues of humans, dolphins, and sharks from the United States

(2007) Boris Johnson-Restrepo et al.   CHEMOSPHERE

Environmental levels, toxicity and human exposure to tributyltin (TBT)-contaminated marine environment. A review

(2007) Blanca Antizar-Ladislao   ENVIRONMENT INTERNATIONAL

Mechanisms of nongenomic actions of thyroid hormone

(2007) Paul J. Davis et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Endocrine effects of tetrabromobisphenol-A (TBBPA) in Wistar rats as tested in a one-generation reproduction study and a subacute toxicity study

(2007) Leo T.M. Van der Ven et al.   TOXICOLOGY