Continuous flow micro-bioreactors for the production of biopharmaceuticals: the effect of geometry, surface texture, and flow rate

Enrichment of tumor-initiating breast cancer cells within a mammosphere-culture microdevice

(2013) Katayoon Saadin et al.   BIOMEDICAL MICRODEVICES

A standalone perfusion platform for drug testing and target validation in micro-vessel networks

(2013) Boyang Zhang et al.   Biomicrofluidics

Investigation of metabolic variability observed in extended fed batch cell culture

(2013) Alan Gilbert et al.   BIOTECHNOLOGY PROGRESS

Organs-on-a-chip for drug discovery

(2013) Šeila Selimović et al.   CURRENT OPINION IN PHARMACOLOGY

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

(2013) Kyung-Jin Jang et al.   Integrative Biology

A novel microfluidic co-culture system for investigation of bacterial cancer targeting

(2013) Jung Woo Hong et al.   LAB ON A CHIP

A biopharmaceutical plant on a chip: continuous micro-devices for the production of monoclonal antibodies

(2013) Lucía D. Garza-García et al.   LAB ON A CHIP

Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules

(2013) I. Rizvi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Study of long-term viability of endothelial cells for lab-on-a-chip devices

(2013) Ioana Voiculescu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Controlling trisulfide modification in recombinant monoclonal antibody produced in fed-batch cell culture

(2012) Rashmi Kshirsagar et al.   BIOTECHNOLOGY AND BIOENGINEERING

Integrated continuous production of recombinant therapeutic proteins

(2012) Veena Warikoo et al.   BIOTECHNOLOGY AND BIOENGINEERING

State-of-the-art in downstream processing of monoclonal antibodies: Process trends in design and validation

(2012) P. A. Marichal-Gallardo et al.   BIOTECHNOLOGY PROGRESS

A multilayer microdevice for cell-based high-throughput drug screening

(2012) Chong Liu et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Engineers are from PDMS-land, Biologists are from Polystyrenia

(2012) Erwin Berthier et al.   LAB ON A CHIP

A multi-shear perfusion bioreactor for investigating shear stress effects in endothelial cell constructs

(2012) Menahem Y. Rotenberg et al.   LAB ON A CHIP

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

A continuous perfusion microplate for cell culture

(2012) Vasiliy N. Goral et al.   LAB ON A CHIP

Marketed therapeutic antibodies compendium

(2012) Janice M. Reichert   mAbs

Systematic Single-Cell Analysis of Pichia pastoris Reveals Secretory Capacity Limits Productivity

(2012) Kerry Routenberg Love et al.   PLoS One

Polymer-Based Microfluidic Devices for Pharmacy, Biology and Tissue Engineering

(2012) Ahmed Alrifaiy et al.   Polymers

Integrated Microdevice for Long-Term Automated Perfusion Culture without Shear Stress and Real-Time Electrochemical Monitoring of Cells

(2011) Lin-Mei Li et al.   ANALYTICAL CHEMISTRY

CHO cells in biotechnology for production of recombinant proteins: current state and further potential

(2011) Jee Yon Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Design and development of microbioreactors for long-term cell culture in controlled oxygen microenvironments

(2011) Hasan E. Abaci et al.   BIOMEDICAL MICRODEVICES

Batch, fed-batch, and microcarrier cultures with CHO cell lines in a pressure-cycle driven miniaturized bioreactor

(2011) Beum Jun Kim et al.   BIOTECHNOLOGY AND BIOENGINEERING

Use of a Plackett-Burman statistical design to determine the effect of selected amino acids on monoclonal antibody production in CHO cells

(2011) I. J. González-Leal et al.   BIOTECHNOLOGY PROGRESS

Enhancement of static incubation time in microfluidic cell culture platforms exploiting extended air–liquid interface

(2011) Nilanjana Bose et al.   LAB ON A CHIP

Defining process design space for monoclonal antibody cell culture

(2010) Susan Fugett Abu-Absi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Fundamentals of microfluidic cell culture in controlled microenvironments

(2010) Edmond W. K. Young et al.   CHEMICAL SOCIETY REVIEWS

An experimental analysis of process parameters to manufacture metallic micro-channels by micro-milling

(2010) Elisa Vázquez et al.   INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY

On the use of CO2 laser induced surface patterns to modify the wettability of poly(methyl methacrylate) (PMMA)

(2010) David Garreth Waugh et al.   OPTICS AND LASERS IN ENGINEERING

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Wettability versus roughness of engineering surfaces

(2010) K.J. Kubiak et al.   WEAR

Critical stresses for cancer cell detachment in microchannels

(2009) Cécile Couzon et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Detachment of captured cancer cells under flow acceleration in a bio-functionalized microchannel

(2009) Luthur Siu Lun Cheung et al.   LAB ON A CHIP

Effect of channel geometry on cell adhesion in microfluidic devices

(2008) James V. Green et al.   LAB ON A CHIP