Increasing the activity of monoclonal antibody therapeutics by continuous chromatography (MCSGP)

Two step capture and purification of IgG2 using multicolumn countercurrent solvent gradient purification (MCSGP)

(2010) T. Müller-Späth et al.   BIOTECHNOLOGY AND BIOENGINEERING

Optimizing model predictive control of the chromatographic multi-column solvent gradient purification (MCSGP) process

(2010) Cristian Grossmann et al.   JOURNAL OF PROCESS CONTROL

Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody

(2009) Josef Vlasak et al.   ANALYTICAL BIOCHEMISTRY

Human antibody Fc deamidation in vivo

(2009) Y. Diana Liu et al.   BIOLOGICALS

Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain

(2009) Boxu Yan et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Glycosylation as a strategy to improve antibody-based therapeutics

(2009) Roy Jefferis   NATURE REVIEWS DRUG DISCOVERY

Role of Cleaning-in-Place in the Purification of mAb Supernatants Using Continuous Cation Exchange Chromatography

(2009) Thomas Müller-Späth et al.   SEPARATION SCIENCE AND TECHNOLOGY

Chromatographic separation of three monoclonal antibody variants using multicolumn countercurrent solvent gradient purification (MCSGP)

(2008) Thomas Müller-Späth et al.   BIOTECHNOLOGY AND BIOENGINEERING

Application of imaging capillary IEF for characterization and quantitative analysis of recombinant protein charge heterogeneity

(2008) Zoran Sosic et al.   ELECTROPHORESIS