Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression Levels

Molecular Pathways: Novel Approaches for Improved Therapeutic Targeting of Hedgehog Signaling in Cancer Stem Cells

(2015) Verline Justilien et al.   CLINICAL CANCER RESEARCH

Hydrodynamic Transfection for Generation of Novel Mouse Models for Liver Cancer Research

(2014) Xin Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Dysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-β-catenin signaling and cell death of the cloaca endoderm and anorectal malformations

(2014) R C-L Ng et al.   CELL DEATH AND DIFFERENTIATION

A soluble form of GAS1 inhibits tumor growth and angiogenesis in a triple negative breast cancer model

(2014) Adriana Jiménez et al.   EXPERIMENTAL CELL RESEARCH

Gene Therapies for Cancer: Strategies, Challenges and Successes

(2014) Swadesh K. Das et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling

(2014) H. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstruction of the Gene Regulatory Network Involved in the Sonic Hedgehog Pathway with a Potential Role in Early Development of the Mouse Brain

(2014) Jinhua Liu et al.   PLoS Computational Biology

Molecular Biology of Liver Cancer Stem Cells

(2014) Naoki Oishi et al.   Liver Cancer

Heparan Sulfate Proteoglycans Containing a Glypican 5 Core and 2-O-Sulfo-iduronic Acid Function as Sonic Hedgehog Co-receptors to Promote Proliferation

(2013) Rochelle M. Witt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of Bmi1, FoxF1, Nanog, and γ-Catenin in Relation to Hedgehog Signaling Pathway in Human Non-small-Cell Lung Cancer

(2013) Ioannis P. Gialmanidis et al.   LUNG

GAS1 induces cell death through an intrinsic apoptotic pathway

(2012) Natanael Zarco et al.   APOPTOSIS

The WIF domain of the human and Drosophila Wif-1 secreted factors confers specificity for Wnt or Hedgehog

(2012) D. Sanchez-Hernandez et al.   DEVELOPMENT

Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer

(2012) Honghong Wang et al.   FEBS Journal

Cdon and Boc: Two transmembrane proteins implicated in cell–cell communication

(2012) Luisa Sanchez-Arrones et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Sulfatase 1 Promotes the Motor Neuron-to-Oligodendrocyte Fate Switch by Activating Shh Signaling in Olig2 Progenitors of the Embryonic Ventral Spinal Cord

(2012) Y. Touahri et al.   JOURNAL OF NEUROSCIENCE

Growth arrest–specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation

(2012) Claudia R.C. van Roeyen et al.   KIDNEY INTERNATIONAL

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Bmi1 Is Required for Hepatic Progenitor Cell Expansion and Liver Tumor Development

(2012) Lingling Fan et al.   PLoS One

The Role of Glypicans in Wnt Inhibitory Factor-1 Activity and the Structural Basis of Wif1's Effects on Wnt and Hedgehog Signaling

(2012) Andrei Avanesov et al.   PLoS Genetics

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Boc and Gas1 Each Form Distinct Shh Receptor Complexes with Ptch1 and Are Required for Shh-Mediated Cell Proliferation

(2011) Luisa Izzi et al.   DEVELOPMENTAL CELL

Overlapping Roles and Collective Requirement for the Coreceptors GAS1, CDO, and BOC in SHH Pathway Function

(2011) Benjamin L. Allen et al.   DEVELOPMENTAL CELL

Cooperation between Shh and IGF-I in promoting myogenic proliferation and differentiation via the MAPK/ERK and PI3K/Akt pathways requires smo activity

(2011) D. Madhala-Levy et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists

(2011) V. Chenna et al.   MOLECULAR CANCER THERAPEUTICS

Complex interactions between genes controlling trafficking in primary cilia

(2011) Polloneal Jymmiel R Ocbina et al.   NATURE GENETICS

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

(2011) J. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atoh1 Inhibits Neuronal Differentiation and Collaborates with Gli1 to Generate Medulloblastoma-Initiating Cells

(2010) O. Ayrault et al.   CANCER RESEARCH

Differential Modulation of Sonic-Hedgehog-Induced Cerebellar Granule Cell Precursor Proliferation by the IGF Signaling Network

(2010) Carla Fernandez et al.   DEVELOPMENTAL NEUROSCIENCE

Down-regulated GAS1 expression correlates with recurrence in stage II and III colorectal cancer☆

(2010) Zheng Jiang et al.   HUMAN PATHOLOGY

Hedgehog signaling in the liver

(2010) Alessia Omenetti et al.   JOURNAL OF HEPATOLOGY

The challenges of liver transplantation for hepatocellular carcinoma on cirrhosis

(2010) Sherrie Bhoori et al.   TRANSPLANT INTERNATIONAL

Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord

(2009) Nicholas Genethliou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Prognostic Significance of Tryptophanyl-tRNA Synthetase in Colorectal Cancer

(2009) A. Ghanipour et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The Gli3 Transcription Factor Expressed in the Thymus Stroma Controls Thymocyte Negative Selection Via Hedgehog-Dependent and -Independent Mechanisms

(2009) A. L. Hager-Theodorides et al.   JOURNAL OF IMMUNOLOGY

Bmi1 Functions as an Oncogene Independent of Ink4A/Arf Repression in Hepatic Carcinogenesis

(2009) C.-R. Xu et al.   MOLECULAR CANCER RESEARCH

The Insulin-Like Growth Factor (IGF) Receptor Type 1 (IGF1R) as an Essential Component of the Signalling Network Regulating Neurogenesis

(2009) Alexander Annenkov   MOLECULAR NEUROBIOLOGY

A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene

(2008) S. Gobeil et al.   GENES & DEVELOPMENT

Survival and function of human thymic dendritic cells are dependent on autocrine Hedgehog signaling

(2008) A. Varas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Evaluation of Gene Promoters for Liver Expression by Hydrodynamic Gene Transfer

(2008) Andrew T. Nguyen et al.   JOURNAL OF SURGICAL RESEARCH

A Novel Gene Signature for Molecular Diagnosis of Human Prostate Cancer by RT-qPCR

(2008) Federica Rizzi et al.   PLoS One