Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components
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Title
Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 108, Issue 4, Pages 1456-1461
Publisher
Proceedings of the National Academy of Sciences
Online
2011-01-06
DOI
10.1073/pnas.1011410108
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Note: Only part of the references are listed.- Cranioectodermal Dysplasia, Sensenbrenner Syndrome, Is a Ciliopathy Caused by Mutations in the IFT122 Gene
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- Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
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- Retrograde Intraflagellar Transport Mutants Identify Complex A Proteins With Multiple Genetic Interactions in Chlamydomonas reinhardtii
- (2009) C. Iomini et al. GENETICS
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- (2009) K. F. Liem et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus
- (2009) J. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process
- (2009) R. Rohatgi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An IFT-A Protein Is Required to Delimit Functionally Distinct Zones in Mechanosensory Cilia
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- Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network
- (2008) E. Dessaud et al. DEVELOPMENT
- FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism
- (2008) Ahryon Cho et al. DEVELOPMENTAL BIOLOGY
- Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4
- (2008) Salvatore Cortellino et al. DEVELOPMENTAL BIOLOGY
- Intraflagellar transport, cilia, and mammalian Hedgehog signaling: Analysis in mouse embryonic fibroblasts
- (2008) Polloneal Jymmiel R. Ocbina et al. DEVELOPMENTAL DYNAMICS
- Hedgehog: functions and mechanisms
- (2008) M. Varjosalo et al. GENES & DEVELOPMENT
- Tetrahymena IFT122Ais not essential for cilia assembly but plays a role in returning IFT proteins from the ciliary tip to the cell body
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- THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
- (2008) Pamela V Tran et al. NATURE GENETICS
- Intraflagellar Transport and Functional Analysis of Genes Required for Flagellum Formation in Trypanosomes
- (2007) Sabrina Absalon et al. MOLECULAR BIOLOGY OF THE CELL
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