Polysomes of Trypanosoma brucei: Association with Initiation Factors and RNA-Binding Proteins

Probing the closed-loop model of mRNA translation in living cells

(2015) Stuart K Archer et al.   RNA Biology

Two related trypanosomatid eIF4G homologues have functional differences compatible with distinct roles during translation initiation

(2015) Danielle MN Moura et al.   RNA Biology

The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis

(2015) Antonio M Rezende et al.   BMC GENOMICS

Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma brucei

(2014) Bryan C Jensen et al.   BMC GENOMICS

The emerging role of RNA-binding proteins in the life cycle ofTrypanosoma brucei

(2014) Nikolay G. Kolev et al.   CELLULAR MICROBIOLOGY

Depletion of the Trypanosome Pumilio Domain Protein PUF2 or of Some Other Essential Proteins Causes Transcriptome Changes Related to Coding Region Length

(2014) Bhaskar Anand Jha et al.   EUKARYOTIC CELL

Trypanosoma brucei Translation Initiation Factor Homolog EIF4E6 Forms a Tripartite Cytosolic Complex with EIF4G5 and a Capping Enzyme Homolog

(2014) Eden R. Freire et al.   EUKARYOTIC CELL

Networks of gene expression regulation in Trypanosoma brucei

(2014) C.E. Clayton   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels

(2014) Abeer Fadda et al.   MOLECULAR MICROBIOLOGY

Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages

(2014) Juan-José Vasquez et al.   NUCLEIC ACIDS RESEARCH

Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks

(2014) Aditi Singh et al.   NUCLEIC ACIDS RESEARCH

Two splicing factors carrying serine-arginine motifs, TSR1 and TSR1IP, regulate splicing, mRNA stability, and rRNA processing inTrypanosoma brucei

(2014) Sachin Kumar Gupta et al.   RNA Biology

eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation inTrypanosoma brucei

(2014) Eden R. Freire et al.   RNA

A Genome-Wide Tethering Screen Reveals Novel Potential Post-Transcriptional Regulators in Trypanosoma brucei

(2014) Esteban D. Erben et al.   PLoS Pathogens

Basal Splicing Factors Regulate the Stability of Mature mRNAs in Trypanosomes

(2013) Sachin Kumar Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The hnRNP F/H homologue of Trypanosoma brucei is differentially expressed in the two life cycle stages of the parasite and regulates splicing and mRNA stability

(2013) Sachin Kumar Gupta et al.   NUCLEIC ACIDS RESEARCH

The Regulation of Trypanosome Gene Expression by RNA-Binding Proteins

(2013) Christine Clayton   PLoS Pathogens

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

Gene duplication in trypanosomatids – Two DED1 paralogs are functionally redundant and differentially expressed during the life cycle

(2012) Alexandra Zinoviev et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts

(2012) Alexander G. Baltz et al.   MOLECULAR CELL

Expression of the RNA recognition motif protein RBP10 promotes a bloodstream-form transcript pattern in Trypanosoma brucei

(2012) Martin Wurst et al.   MOLECULAR MICROBIOLOGY

Comparative SILAC Proteomic Analysis of Trypanosoma brucei Bloodstream and Procyclic Lifecycle Stages

(2012) Michael D. Urbaniak et al.   PLoS One

Alterations in DRBD3 Ribonucleoprotein Complexes in Response to Stress in Trypanosoma brucei

(2012) Sandra M. Fernández-Moya et al.   PLoS One

The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism

(2012) A. Das et al.   RNA

Trans-splicing in trypanosomes: machinery and its impact on the parasite transcriptome

(2011) Shulamit Michaeli   Future Microbiology

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

(2011) S. Alsford et al.   GENOME RESEARCH

A novel 4E-interacting protein in Leishmania is involved in stage-specific translation pathways

(2011) Alexandra Zinoviev et al.   NUCLEIC ACIDS RESEARCH

Is There a Classical Nonsense-Mediated Decay Pathway in Trypanosomes?

(2011) Praveen Delhi et al.   PLoS One

The four trypanosomatid eIF4E homologues fall into two separate groups, with distinct features in primary sequence and biological properties

(2010) Eden R. Freire et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Time-dependent increase in ribosome processivity

(2010) J. M. Bonderoff et al.   NUCLEIC ACIDS RESEARCH

Trans-acting proteins regulating mRNA maturation, stability and translation in trypanosomatids

(2010) Susanne Kramer et al.   TRENDS IN PARASITOLOGY

Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E–eIF4G interactions

(2009) Yael Yoffe et al.   NUCLEIC ACIDS RESEARCH

Multiple roles for polypyrimidine tract binding (PTB) proteins in trypanosome RNA metabolism

(2009) M. Z. Stern et al.   RNA

The RACK1 signal anchor protein fromTrypanosoma bruceiassociates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis

(2008) Sandesh Regmi et al.   MOLECULAR MICROBIOLOGY

The RNA-binding protein Tb DRBD3 regulates the stability of a specific subset of mRNAs in trypanosomes

(2008) Antonio M. Estévez   NUCLEIC ACIDS RESEARCH