Cardiac and skeletal muscles show molecularly distinct responses to cancer cachexia

Disruption of MEF2C signaling and loss of sarcomeric and mitochondrial integrity in cancer-induced skeletal muscle wasting

(2016) Angie M. Y. Shum et al.   Aging-US

Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia

(2015) Sarah M Judge et al.   BMC CANCER

Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1

(2014) Sue C. Bodine et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Childhood Hypophosphatasia with Homozygous Mutation ofALPL

(2014) Supamit Ukarapong et al.   Endocrine Practice

Cardiac cachexia remains a clinical challenge

(2014) R. P. Vincent   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Emerging Biomarkers in Heart Failure and Cardiac Cachexia

(2014) Goran Loncar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

C26 Cancer-Induced Muscle Wasting Is IKKβ-Dependent and NF-kappaB-Independent

(2014) Evangeline W. Cornwell et al.   PLoS One

Mitochondria-mediated apoptosis in mammals

(2014) Shunbin Xiong et al.   Protein & Cell

Modeling human cancer cachexia in colon 26 tumor-bearing adult mice

(2014) Erin E. Talbert et al.   Journal of Cachexia Sarcopenia and Muscle

Rosiglitazone reduces body wasting and improves survival in a rat model of cancer cachexia

(2013) Katja Trobec et al.   NUTRITION

Severity of cardiomyopathy associated with adenine nucleotide translocator-1 deficiency correlates with mtDNA haplogroup

(2013) Kevin A. Strauss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transient Infantile Hypertriglyceridemia, Fatty Liver, and Hepatic Fibrosis Caused by Mutated GPD1, Encoding Glycerol-3-Phosphate Dehydrogenase 1

(2012) Lina Basel-Vanagaite et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

(2012) Kenneth C.H. Fearon et al.   Cell Metabolism

Study of LPIN1, LPIN2 and LPIN3 in rhabdomyolysis and exercise-induced myalgia

(2012) Caroline Michot et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Cancer cachexia: malignant inflammation, tumorkines, and metabolic mayhem

(2012) Maria Tsoli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cancer Cachexia: Molecular Targets and Pathways for Diagnosis and Drug Intervention

(2012) Angie M.Y. Shum et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

NF-κB Inhibition Protects against Tumor-Induced Cardiac Atrophy in Vivo

(2011) Ashley Wysong et al.   AMERICAN JOURNAL OF PATHOLOGY

A phase 2 study of oral MKC-1, an inhibitor of importin-β, tubulin, and the mTOR pathway in patients with unresectable or metastatic pancreatic cancer

(2011) Jason E. Faris et al.   INVESTIGATIONAL NEW DRUGS

Complete loss of expression of theANT1gene causing cardiomyopathy and myopathy

(2011) Andoni Echaniz-Laguna et al.   JOURNAL OF MEDICAL GENETICS

Definition and classification of cancer cachexia: an international consensus

(2011) Kenneth Fearon et al.   LANCET ONCOLOGY

Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range

(2011) J. Bachmann et al.   Molecular Systems Biology

Genetic Variant of the Scavenger Receptor BI in Humans

(2011) Menno Vergeer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Minocycline exerts uncoupling and inhibiting effects on mitochondrial respiration through adenine nucleotide translocase inhibition

(2011) Maria D. Cuenca-Lopez et al.   PHARMACOLOGICAL RESEARCH

Cancer Induces Cardiomyocyte Remodeling and Hypoinnervation in the Left Ventricle of the Mouse Heart

(2011) Christian Mühlfeld et al.   PLoS One

STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia

(2011) Andrea Bonetto et al.   PLoS One

Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner

(2010) P. F. Cosper et al.   CANCER RESEARCH

Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

(2010) Xiaolan Zhou et al.   CELL

Cevoglitazar, a Novel Peroxisome Proliferator-Activated Receptor-α/γ Dual Agonist, Potently Reduces Food Intake and Body Weight in Obese Mice and Cynomolgus Monkeys

(2010) Hong Chen et al.   ENDOCRINOLOGY

The MeCP2/YY1 interaction regulates ANT1 expression at 4q35: novel hints for Rett syndrome pathogenesis

(2010) Greta Forlani et al.   HUMAN MOLECULAR GENETICS

Myocardial dysfunction in an animal model of cancer cachexia

(2010) Hui Xu et al.   LIFE SCIENCES

Association between serum alkaline phosphatase and C-reactive protein in the United States National Health and Nutrition Examination Survey 2005–2006

(2009) Matthew Webber et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Mutations in the ANKRD1 gene encoding CARP are responsible for human dilated cardiomyopathy

(2009) Laëtitia Duboscq-Bidot et al.   EUROPEAN HEART JOURNAL

Aggravation by prostaglandin E2 of interleukin-6-dependent insulin resistance in hepatocytes

(2009) Janin Henkel et al.   HEPATOLOGY

Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice

(2009) Michelle L. Asp et al.   INTERNATIONAL JOURNAL OF CANCER

Niemann-Pick C1 Functions Independently of Niemann-Pick C2 in the Initial Stage of Retrograde Transport of Membrane-impermeable Lysosomal Cargo

(2009) Stephen D. B. Goldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Olanzapine inhibits glycogen synthase kinase-3β: An investigation by docking simulation and experimental validation

(2008) Mohammad K. Mohammad et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cardiac ankyrin repeat protein is a marker of skeletal muscle pathological remodelling

(2008) Lydie Laure et al.   FEBS Journal

Transcriptional deregulation and a missense mutation define ANKRD1 as a candidate gene for total anomalous pulmonary venous return

(2008) Raffaella Cinquetti et al.   HUMAN MUTATION

An Allosteric Circuit in Caspase-1

(2008) Debajyoti Datta et al.   JOURNAL OF MOLECULAR BIOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH