Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range

Metal ion-mobilizing additives for comprehensive detection of femtomole amounts of phosphopeptides by reversed phase LC-MS

(2010) Joerg Seidler et al.   AMINO ACIDS

Recombinant Human Erythropoietin Antagonizes Trastuzumab Treatment of Breast Cancer Cells via Jak2-Mediated Src Activation and PTEN Inactivation

(2010) Ke Liang et al.   CANCER CELL

Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling

(2010) Tim Maiwald et al.   FEBS Journal

Classic and contemporary approaches to modeling biochemical reactions

(2010) W. W. Chen et al.   GENES & DEVELOPMENT

Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response

(2010) Ofer Feinerman et al.   Molecular Systems Biology

Signalling ballet in space and time

(2010) Boris N. Kholodenko et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

One-source peptide/phosphopeptide standards for accurate phosphorylation degree determination

(2010) Bettina Hahn et al.   PROTEOMICS

Covering a Broad Dynamic Range: Information Processing at the Erythropoietin Receptor

(2010) V. Becker et al.   SCIENCE

Analysis of autophosphorylation sites in the recombinant catalytic subunit alpha of cAMP-dependent kinase by nano-UPLC–ESI–MS/MS

(2009) Joerg Seidler et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

(2009) A. Raue et al.   BIOINFORMATICS

A new polycythaemia vera-associated SOCS3 SH2 mutant (SOCS3F136L) cannot regulate erythropoietin responses

(2009) Yvonne Suessmuth et al.   BRITISH JOURNAL OF HAEMATOLOGY

Theoretical and experimental analysis links isoform- specific ERK signalling to cell fate decisions

(2009) Marcel Schilling et al.   Molecular Systems Biology

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

(2009) Sabrina L. Spencer et al.   NATURE

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1

(2008) M. A. Kerenyi et al.   BLOOD

Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2

(2008) F. Grebien et al.   BLOOD

Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression

(2008) B.-M. Zhu et al.   BLOOD

Aberrant signal transduction pathways in myeloproliferative neoplasms

(2008) J Kota et al.   LEUKEMIA

Recurrent design patterns in the feedback regulation of the mammalian signalling network

(2008) Stefan Legewie et al.   Molecular Systems Biology

Downregulation of Signal Transducer and Activator of Transcription 5 (STAT5) in CD34+Cells Promotes Megakaryocytic Development, Whereas Activation of STAT5 Drives Erythropoiesis

(2008) Sandra G. Olthof et al.   STEM CELLS