Antidiabetic plants improving insulin sensitivity

Ameliorating effect and potential mechanism of Rehmannia glutinosa oligosaccharides on the impaired glucose metabolism in chronic stress rats fed with high-fat diet

(2014) Ruxue Zhang et al.   PHYTOMEDICINE

Antioxidant, Anti-inflammatory, and Hypoglycemic Effects of the Leaf Extract from Passiflora nitida Kunth

(2013) Carlos Victor Montefusco-Pereira et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer

(2013) D. G. Hardie   DIABETES

Ilexgenin A Obtained fromIlex hainanensisMerr. Improves Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats

(2013) Wei-xi Cui et al.   DRUG DEVELOPMENT RESEARCH

Herbal Therapies for Type 2 Diabetes Mellitus: Chemistry, Biology, and Potential Application of Selected Plants and Compounds

(2013) Cicero L. T. Chang et al.   Evidence-based Complementary and Alternative Medicine

Flavonoids from Tetrastigma obtectum enhancing glucose consumption in insulin-resistance HepG2 cells via activating AMPK

(2013) Mei-Na Jin et al.   FITOTERAPIA

Ethanol extract of the Prunus mume fruits stimulates glucose uptake by regulating PPAR-γ in C2C12 myotubes and ameliorates glucose intolerance and fat accumulation in mice fed a high-fat diet

(2013) Eun Ju Shin et al.   FOOD CHEMISTRY

Sutherlandia frutescens prevents changes in diabetes-related gene expression in a fructose-induced insulin resistant cell model

(2013) S. Williams et al.   JOURNAL OF ETHNOPHARMACOLOGY

Wild blueberry (Vaccinium angustifolium) consumption improves inflammatory status in the obese Zucker rat model of the metabolic syndrome

(2013) Stefano Vendrame et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Oleanolic acid improves hepatic insulin resistance via antioxidant, hypolipidemic and anti-inflammatory effects

(2013) Xin Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Metabolic effects of aloe vera gel complex in obese prediabetes and early non-treated diabetic patients: Randomized controlled trial

(2013) Ho-Chun Choi et al.   NUTRITION

Efficacy and safety of Elaeis guineensis and Ficus deltoidea leaf extracts in adults with pre-diabetes

(2013) Douglas S Kalman et al.   Nutrition Journal

Acylated dolabellane-type diterpenes from Nigella sativa seeds with triglyceride metabolism-promoting activity in high glucose-pretreated HepG2 cells

(2013) Toshio Morikawa et al.   Phytochemistry Letters

Resveratrol induces insulin gene expression in mouse pancreatic α-cells

(2013) Sherwin Xie et al.   Cell and Bioscience

Clinical Implications of Adipocytokines and Newly Emerging Metabolic Factors with Relation to Insulin Resistance and Cardiovascular Health

(2013) Sung Hee Choi et al.   Frontiers in Endocrinology

Strategies for preventing type 2 diabetes: an update for clinicians

(2013) Kaivan Khavandi et al.   Therapeutic Advances in Chronic Disease

Stevioside ameliorates high-fat diet-induced insulin resistance and adipose tissue inflammation by downregulating the NF-κB pathway

(2012) Zhiquan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pectinase-Processed Ginseng Radix (GINST) Ameliorates Hyperglycemia and Hyperlipidemia in High Fat Diet-Fed ICR Mice

(2012) Hai-Dan Yuan et al.   Biomolecules & Therapeutics

The roots of Atractylodes japonica Koidzumi promote adipogenic differentiation via activation of the insulin signaling pathway in 3T3-L1 cells

(2012) Yunkyung Han et al.   BMC Complementary and Alternative Medicine

Improvements of insulin resistance in ovariectomized rats by a novel phytoestrogen from Curcuma comosa Roxb

(2012) Mujalin Prasannarong et al.   BMC Complementary and Alternative Medicine

Effect of a novel proteoglycan PTP1B inhibitor from Ganoderma lucidum on the amelioration of hyperglycaemia and dyslipidaemia in db/db mice

(2012) Chen-Dong Wang et al.   BRITISH JOURNAL OF NUTRITION

Cardioprotective and antihypertensive effects of Enicostemma littorale Blume extract in fructose-fed rats

(2012) Niraj M. Bhatt et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Preventive Effects of Flavonoid Extracts from Ilex hainanensisMerr. on Rats with Hepatic Steatosis Induced by a High-Fat Diet

(2012) Xiang-lan Wei et al.   DRUG DEVELOPMENT RESEARCH

Larix laricina, an Antidiabetic Alternative Treatment from the Cree of Northern Quebec Pharmacopoeia, Decreases Glycemia and Improves Insulin SensitivityIn Vivo

(2012) Despina Harbilas et al.   Evidence-based Complementary and Alternative Medicine

Animal Models as Tools to Investigate Antidiabetic and Anti-Inflammatory Plants

(2012) Mohamed Eddouks et al.   Evidence-based Complementary and Alternative Medicine

Medicinal Mushrooms for Glycemic Control in Diabetes Mellitus: History, Current Status, Future Perspectives, and Unsolved Problems (Review)

(2012) Hui-Chen Lo et al.   INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS

Populus balsamifera L. (Salicaceae) mitigates the development of obesity and improves insulin sensitivity in a diet-induced obese mouse model

(2012) Despina Harbilas et al.   JOURNAL OF ETHNOPHARMACOLOGY

Rhodiola crenulata root ameliorates derangements of glucose and lipid metabolism in a rat model of the metabolic syndrome and type 2 diabetes

(2012) Jianwei Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antidiabetic effects of Justicia spicigera Schltdl (Acanthaceae)

(2012) Rolffy Ortiz-Andrade et al.   JOURNAL OF ETHNOPHARMACOLOGY

Preventive and curative effect of Trigonella foenum-graecum L. seeds in C57BL/6J models of type 2 diabetes induced by high-fat diet

(2012) Nawel Hamza et al.   JOURNAL OF ETHNOPHARMACOLOGY

Jerusalem artichoke and chungkookjang additively improve insulin secretion and sensitivity in diabetic rats

(2012) Hye Jeong Yang et al.   Nutrition & Metabolism

Borapetoside C from Tinospora crispa improves insulin sensitivity in diabetic mice

(2012) Chi-Tun Ruan et al.   PHYTOMEDICINE

Effect of Water Extracts from Edible Myrtaceae Plants on Uptake of 2-(n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose in TNF-α-Treated FL83B Mouse Hepatocytes

(2012) Wen-Chang Chang et al.   PHYTOTHERAPY RESEARCH

Effect ofSutherlandia frutescenson the Lipid Metabolism in an Insulin Resistant Rat Model and 3T3-L1 Adipocytes

(2012) Janine MacKenzie et al.   PHYTOTHERAPY RESEARCH

Ratanhiaphenol III from Ratanhiae Radix is a PTP1B Inhibitor

(2012) Elke Heiss et al.   PLANTA MEDICA

Amorfrutins are potent antidiabetic dietary natural products

(2012) C. Weidner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of hypoglycemic activity of the leaves of Malva parviflora in streptozotocin-induced diabetic rats

(2012) Rosa Martha Perez Gutierrez   Food & Function

AMP-activated protein kinase: A potential target for ginsenosides?

(2011) Mi Song Jung et al.   ARCHIVES OF PHARMACAL RESEARCH

Large enhancement of skeletal muscle cell glucose uptake and suppression of hepatocyte glucose-6-phosphatase activity by weak uncouplers of oxidative phosphorylation

(2011) Louis C. Martineau   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanism of action of natural products used in the treatment of diabetes mellitus

(2011) Pranav Kumar Prabhakar et al.   Chinese Journal of Integrative Medicine

Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner

(2011) Natasha Jaiswal et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Chemical constituents of Kigelia pinnata twigs and their GLUT4 translocation modulatory effect in skeletal muscle cells

(2011) Mohammad Faheem Khan et al.   FITOTERAPIA

Fenugreek Improves Diet-induced Metabolic Disorders in Rats

(2011) E. Muraki et al.   HORMONE AND METABOLIC RESEARCH

Hypoglycemic effects of MDG-1, a polysaccharide derived from Ophiopogon japonicas, in the ob/ob mouse model of type 2 diabetes mellitus

(2011) Jie Xu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The efficacy of Prosopis glandulosa as antidiabetic treatment in rat models of diabetes and insulin resistance

(2011) C. George et al.   JOURNAL OF ETHNOPHARMACOLOGY

The lignan-rich fractions of Fructus Schisandrae improve insulin sensitivity via the PPAR-γ pathways in in vitro and in vivo studies

(2011) Dae Young Kwon et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hypoglycemic and hypolipidemic effects of Coriandrum sativum L. in Meriones shawi rats

(2011) Abderrahmane Aissaoui et al.   JOURNAL OF ETHNOPHARMACOLOGY

Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: mechanistic insights

(2011) Jung-Mi Yun et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Stimulation of Glucose Uptake and Improvement of Insulin Resistance by Aromadendrin

(2011) Wei Yun Zhang et al.   PHARMACOLOGY

Magnolia dealbata Zucc and its active principles honokiol and magnolol stimulate glucose uptake in murine and human adipocytes using the insulin-signaling pathway

(2011) Angel Josabad Alonso-Castro et al.   PHYTOMEDICINE

Antidiabetic effect of a newly identified component of Opuntia dillenii polysaccharides

(2011) L.Y. Zhao et al.   PHYTOMEDICINE

Decursin, an Active Compound Isolated from Angelica gigas, Inhibits Fat Accumulation, Reduces Adipocytokine Secretion and Improves Glucose Tolerance in Mice Fed a High-Fat Diet

(2011) Jin-Taek Hwang et al.   PHYTOTHERAPY RESEARCH

Insights into the Molecular Mechanisms of the Anti-Atherogenic Actions of Flavonoids in Normal and Obese Mice

(2011) Elena V. Shabrova et al.   PLoS One

Small molecules from natural sources, targeting signaling pathways in diabetes

(2010) Qiong Liu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Antidiabetic properties of purified polysaccharide from Hedysarum polybotrys

(2010) Fangdi Hu et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Gastrodia elata Blume water extracts improve insulin resistance by decreasing body fat in diet-induced obese rats: vanillin and 4-hydroxybenzaldehyde are the bioactive candidates

(2010) Sunmin Park et al.   EUROPEAN JOURNAL OF NUTRITION

Anti-inflammatory and antioxidant effects of a hypoglycemic fructan fraction from Psacalium peltatum (H.B.K.) Cass. in streptozotocin-induced diabetes mice

(2010) F.J. Alarcon-Aguilar et al.   JOURNAL OF ETHNOPHARMACOLOGY

Prevention of type 2 diabetes induced by high fat diet in the C57BL/6J mouse by two medicinal plants used in traditional treatment of diabetes in the east of Algeria

(2010) Nawel Hamza et al.   JOURNAL OF ETHNOPHARMACOLOGY

Scoparia dulcis (SDF7) endowed with glucose uptake properties on L6 myotubes compared insulin

(2010) Joo Ee Beh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mechanism of anti-hyperglycemic action of Vatairea macrocarpa (Leguminosae): Investigation in peripheral tissues

(2010) Paula Domingues Baviloni et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cornus kousa F.Buerger ex Miquel increases glucose uptake through activation of peroxisome proliferator-activated receptor γ and insulin sensitization

(2010) Daeyoung Kim et al.   JOURNAL OF ETHNOPHARMACOLOGY

Treatment of high fat diet induced type 2 diabetes in C57BL/6J mice by two medicinal plants used in traditional treatment of diabetes in the east of Algeria

(2010) Nawel Hamza et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antidiabetic effect of Symplocos cochinchinensis (Lour.) S. Moore. in type 2 diabetic rats

(2010) Christudas Sunil et al.   JOURNAL OF ETHNOPHARMACOLOGY

Bioactives in Blueberries Improve Insulin Sensitivity in Obese, Insulin-Resistant Men and Women

(2010) April J. Stull et al.   JOURNAL OF NUTRITION

Stimulation of AMP-activated protein kinase and enhancement of basal glucose uptake in muscle cells by quercetin and quercetin glycosides, active principles of the antidiabetic medicinal plant Vaccinium vitis-idaea

(2010) Hoda M. Eid et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Hypoglycemic activities of A- and B-type procyanidin oligomer-rich extracts from different Cinnamon barks

(2010) Zhaolian Lu et al.   PHYTOMEDICINE

Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) γ

(2010) Kathrine B. Christensen et al.   PHYTOTHERAPY RESEARCH

Constituents fromCistus salvifolius(Cistaceae) Activate Peroxisome Proliferator-Activated Receptor-γbut Not -δand Stimulate Glucose Uptake by Adipocytes

(2010) Claudia Kühn et al.   PLANTA MEDICA

Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism

(2010) Tsuyoshi Goto et al.   PPAR Research

3β-taraxerol of Mangifera indica, a PI3K dependent dual activator of glucose transport and glycogen synthesis in 3T3-L1 adipocytes

(2009) Kadapakkam Nandabalan Sangeetha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Yacon syrup: Beneficial effects on obesity and insulin resistance in humans

(2009) Susana Genta et al.   CLINICAL NUTRITION

Preventive effect of Tinospora cordifolia against high-fructose diet-induced insulin resistance and oxidative stress in male Wistar rats

(2009) Singareddy Sreenivasa Reddy et al.   FOOD AND CHEMICAL TOXICOLOGY

Beneficiary Effect ofTinospora cordifoliaAgainst High-fructose Diet Induced Abnormalities in Carbohydrate and Lipid Metabolism in Wistar Rats

(2009) S. Sreenivasa Reddy et al.   HORMONE AND METABOLIC RESEARCH

Antidiabetic activities of Tecoma stans (L.) Juss. ex Kunth

(2009) L. Aguilar-Santamaría et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antidiabetic effects of Artemisia sphaerocephala Krasch. gum, a novel food additive in China, on streptozotocin-induced type 2 diabetic rats

(2009) Xiao-Hui Xing et al.   JOURNAL OF ETHNOPHARMACOLOGY

The antidiabetic plants Tecoma stans (L.) Juss. ex Kunth (Bignoniaceae) and Teucrium cubense Jacq (Lamiaceae) induce the incorporation of glucose in insulin-sensitive and insulin-resistant murine and human adipocytes

(2009) Angel Josabad Alonso-Castro et al.   JOURNAL OF ETHNOPHARMACOLOGY

Activation of PPARγ by Metabolites from the Flowers of Purple Coneflower (Echinacea purpurea)

(2009) Kathrine B. Christensen et al.   JOURNAL OF NATURAL PRODUCTS

Anti-diabetic effect of methylswertianin and bellidifolin from Swertia punicea Hemsl. and its potential mechanism

(2009) L.-Y. Tian et al.   PHYTOMEDICINE

Sutherlandia frutescenslimits the development of insulin resistance by decreasing plasma free fatty acid levels

(2009) Janine MacKenzie et al.   PHYTOTHERAPY RESEARCH

Cecropia obtusifolia Bertol and its active compound, chlorogenic acid, stimulate 2-NBDglucose uptake in both insulin-sensitive and insulin-resistant 3T3 adipocytes

(2008) Angel Josabad Alonso-Castro et al.   JOURNAL OF ETHNOPHARMACOLOGY

The anti-diabetic properties of Guazuma ulmifolia Lam are mediated by the stimulation of glucose uptake in normal and diabetic adipocytes without inducing adipogenesis

(2008) Angel Josabad Alonso-Castro et al.   JOURNAL OF ETHNOPHARMACOLOGY

Triterpenoids from the Leaves ofDiospyros kaki(Persimmon) and Their Inhibitory Effects on Protein Tyrosine Phosphatase 1B

(2008) Phuong Thien Thuong et al.   JOURNAL OF NATURAL PRODUCTS

The functional assessment ofAlpinia priceion metabolic syndrome induced by sucrose-containing drinking water in mice

(2008) Yi-Chun Chou et al.   PHYTOTHERAPY RESEARCH

Antidiabetic activity of Vatairea macrocarpa extract in rats

(2007) Helder C. Oliveira et al.   JOURNAL OF ETHNOPHARMACOLOGY