Guanosine protects C6 astroglial cells against azide-induced oxidative damage: a putative role of heme oxygenase 1

Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats

(2014) Bruna Bellaver et al.   TOXICOLOGY IN VITRO

AMPA receptors as a molecular target in epilepsy therapy

(2013) M. A. Rogawski   ACTA NEUROLOGICA SCANDINAVICA

Mitochondrial involvement and oxidative stress in temporal lobe epilepsy

(2013) Shane Rowley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipoic acid increases glutamate uptake, glutamine synthetase activity and glutathione content in C6 astrocyte cell line

(2013) Juliana Kleinkauf-Rocha et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions

(2013) Tharine Dal-Cim et al.   JOURNAL OF NEUROCHEMISTRY

Extracellular cyclic GMP and its derivatives GMP and guanosine protect from oxidative glutamate toxicity

(2013) Philipp Albrecht et al.   NEUROCHEMISTRY INTERNATIONAL

AMPA Receptor Properties are Modulated in the Early Stages Following Pilocarpine-induced Status Epilepticus

(2013) Isabella Russo et al.   NEUROMOLECULAR MEDICINE

Characterization of Adult Rat Astrocyte Cultures

(2013) Débora Guerini Souza et al.   PLoS One

Heme Oxygenase-1 Regulates Matrix Metalloproteinase MMP-1 Secretion and Chondrocyte Cell Death via Nox4 NADPH Oxidase Activity in Chondrocytes

(2013) Francis Rousset et al.   PLoS One

Resveratrol Protects C6 Astrocyte Cell Line against Hydrogen Peroxide-Induced Oxidative Stress through Heme Oxygenase 1

(2013) André Quincozes-Santos et al.   PLoS One

Gliopreventive effects of guanosine against glucose deprivation in vitro

(2013) André Quincozes-Santos et al.   Purinergic Signalling

Formate generated by cellular oxidation of formaldehyde accelerates the glycolytic flux in cultured astrocytes

(2012) Ketki Tulpule et al.   GLIA

Astrocytic regulation of glutamate homeostasis in epilepsy

(2012) Douglas A. Coulter et al.   GLIA

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

Activation of Neuronal NMDA Receptors Induces Superoxide-Mediated Oxidative Stress in Neighboring Neurons and Astrocytes

(2012) R. C. Reyes et al.   JOURNAL OF NEUROSCIENCE

Guanosine protects against reperfusion injury in rat brains after ischemic stroke

(2012) Barry J. Connell et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cholinergic Precursors Modulate the Expression of Heme Oxigenase-1, p21 During Astroglial Cell Proliferation and Differentiation in Culture

(2012) V. Bramanti et al.   NEUROCHEMICAL RESEARCH

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway

(2012) Tharine Dal-Cim et al.   NEUROCHEMISTRY INTERNATIONAL

Resveratrol Prevents Ammonia Toxicity in Astroglial Cells

(2012) Larissa Daniele Bobermin et al.   PLoS One

Resveratrol modulates astroglial functions: neuroprotective hypothesis

(2011) André Quincozes-Santos et al.   Annals of the New York Academy of Sciences

Systemic administration of guanosine promotes functional and histological improvement following an ischemic stroke in rats

(2011) Michel P. Rathbone et al.   BRAIN RESEARCH

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Nuclear Factor Erythroid 2-Related Factor 2 Facilitates Neuronal Glutathione Synthesis by Upregulating Neuronal Excitatory Amino Acid Transporter 3 Expression

(2011) C. Escartin et al.   JOURNAL OF NEUROSCIENCE

Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion

(2011) Marcelo Ganzella et al.   NEUROLOGICAL SCIENCES

Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca2+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake

(2011) T. Dal-Cim et al.   NEUROSCIENCE

Resveratrol Protects Rats from Aβ-induced Neurotoxicity by the Reduction of iNOS Expression and Lipid Peroxidation

(2011) Tai-Chun Huang et al.   PLoS One

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

Heme oxygenase 1: Another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule

(2010) Stéphane Bastianetto et al.   EXPERIMENTAL NEUROLOGY

Resveratrol protects against experimental stroke: Putative neuroprotective role of heme oxygenase 1

(2010) Yoshihito Sakata et al.   EXPERIMENTAL NEUROLOGY

Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases

(2010) Moonhee Lee et al.   FASEB JOURNAL

Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death

(2010) Masayuki Fukui et al.   FREE RADICAL BIOLOGY AND MEDICINE

After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult

(2010) Florencia Arredondo et al.   FREE RADICAL BIOLOGY AND MEDICINE

NOX Enzymes in the Central Nervous System: From Signaling to Disease

(2009) Silvia Sorce et al.   ANTIOXIDANTS & REDOX SIGNALING

The Orbital Ground State of the Azide−Substrate Complex of Human Heme Oxygenase Is an Indicator of Distal H-Bonding: Implications for the Enzyme Mechanism†

(2009) Hiroshi Ogura et al.   BIOCHEMISTRY

Mitochondria, oxidative stress, and temporal lobe epilepsy

(2009) Simon Waldbaum et al.   EPILEPSY RESEARCH

Spinal mechanisms of antinociceptive action caused by guanosine in mice

(2009) André P. Schmidt et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

(2009) Angela M Brennan et al.   NATURE NEUROSCIENCE

The Janus Face of Resveratrol in Astroglial Cells

(2009) André Quincozes-Santos et al.   NEUROTOXICITY RESEARCH

Glucose and NADPH oxidase drive neuronal superoxide formation in stroke

(2008) Sang Won Suh et al.   ANNALS OF NEUROLOGY

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutamine synthetase becomes nitrated and its activity is reduced during repetitive seizure activity in the pentylentetrazole model of epilepsy

(2008) Hans-J. Bidmon et al.   EPILEPSIA

Importance of Schedule of Administration in the Therapeutic Efficacy of Guanosine: Early Intervention After Injury Enhances Glutamate Uptake in Model of Hypoxia-ischemia

(2008) M. B. Moretto et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

(2008) M. R. Vargas et al.   JOURNAL OF NEUROSCIENCE

Growth Factors and Steroid Mediated Regulation of Cytoskeletal Protein Expression in Serum-Deprived Primary Astrocyte Cultures

(2008) Vincenzo Bramanti et al.   NEUROCHEMICAL RESEARCH

Cellular Stress Response: A Novel Target for Chemoprevention and Nutritional Neuroprotection in Aging, Neurodegenerative Disorders and Longevity

(2008) Vittorio Calabrese et al.   NEUROCHEMICAL RESEARCH

The undertow of sulfur metabolism on glutamatergic neurotransmission

(2008) Ruma Banerjee et al.   TRENDS IN BIOCHEMICAL SCIENCES

TGFβ1 and TNFα potentiate nitric oxide production in astrocyte cultures by recruiting distinct subpopulations of cells to express NOS-2

(2007) Mary E. Hamby et al.   NEUROCHEMISTRY INTERNATIONAL

Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen–glucose deprivation

(2007) Scheyla P.B. Oleskovicz et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroprotective effects of guanosine on stroke models in vitro and in vivo

(2007) Ruby Chang et al.   NEUROSCIENCE LETTERS