Gliopreventive effects of guanosine against glucose deprivation in vitro

NDRG2 Is a Novel p53-Associated Regulator of Apoptosis in C6-Originated Astrocytes Exposed to Oxygen-Glucose Deprivation

(2013) Yan Li et al.   PLoS One

Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide–cGMP and PI3K/mTOR pathways

(2012) Luis E.B. Bettio et al.   BEHAVIOURAL BRAIN RESEARCH

Astrocytic regulation of glutamate homeostasis in epilepsy

(2012) Douglas A. Coulter et al.   GLIA

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

Guanosine protects against reperfusion injury in rat brains after ischemic stroke

(2012) Barry J. Connell et al.   JOURNAL OF NEUROSCIENCE RESEARCH

High-Glucose and S100B Stimulate Glutamate Uptake in C6 Glioma Cells

(2012) Ana Carolina Tramontina et al.   NEUROCHEMICAL RESEARCH

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway

(2012) Tharine Dal-Cim et al.   NEUROCHEMISTRY INTERNATIONAL

Glucose depletion activates mmu-miR-466h-5p expression through oxidative stress and inhibition of histone deacetylation

(2012) A. Druz et al.   NUCLEIC ACIDS RESEARCH

Resveratrol Prevents Ammonia Toxicity in Astroglial Cells

(2012) Larissa Daniele Bobermin et al.   PLoS One

Resveratrol modulates astroglial functions: neuroprotective hypothesis

(2011) André Quincozes-Santos et al.   Annals of the New York Academy of Sciences

Systemic administration of guanosine promotes functional and histological improvement following an ischemic stroke in rats

(2011) Michel P. Rathbone et al.   BRAIN RESEARCH

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Nuclear Factor Erythroid 2-Related Factor 2 Facilitates Neuronal Glutathione Synthesis by Upregulating Neuronal Excitatory Amino Acid Transporter 3 Expression

(2011) C. Escartin et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition

(2011) Simone Molz et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion

(2011) Marcelo Ganzella et al.   NEUROLOGICAL SCIENCES

Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca2+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake

(2011) T. Dal-Cim et al.   NEUROSCIENCE

Astrocyte–neuron metabolic relationships: for better and for worse

(2011) Igor Allaman et al.   TRENDS IN NEUROSCIENCES

Basic fibroblast growth factor promotes glial cell-derived neurotrophic factor gene expression mediated by activation of ERK5 in rat C6 glioma cells

(2010) Yutaro Obara et al.   CELLULAR SIGNALLING

Heme oxygenase 1: Another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule

(2010) Stéphane Bastianetto et al.   EXPERIMENTAL NEUROLOGY

Resveratrol protects against experimental stroke: Putative neuroprotective role of heme oxygenase 1

(2010) Yoshihito Sakata et al.   EXPERIMENTAL NEUROLOGY

Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases

(2010) Moonhee Lee et al.   FASEB JOURNAL

Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death

(2010) Masayuki Fukui et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effect of Resveratrol on Gliotransmitter Levels and p38 Activities in Cultured Astrocytes

(2010) Hao Zhou et al.   NEUROCHEMICAL RESEARCH

Spinal mechanisms of antinociceptive action caused by guanosine in mice

(2009) André P. Schmidt et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glycogen Metabolism as a Marker of Astrocyte Differentiation

(2009) JF Brunet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Janus Face of Resveratrol in Astroglial Cells

(2009) André Quincozes-Santos et al.   NEUROTOXICITY RESEARCH

Actions of redox-active compound resveratrol under hydrogen peroxide insult in C6 astroglial cells

(2009) André Quincozes-Santos et al.   TOXICOLOGY IN VITRO

Glucose and NADPH oxidase drive neuronal superoxide formation in stroke

(2008) Sang Won Suh et al.   ANNALS OF NEUROLOGY

Importance of Schedule of Administration in the Therapeutic Efficacy of Guanosine: Early Intervention After Injury Enhances Glutamate Uptake in Model of Hypoxia-ischemia

(2008) M. B. Moretto et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Astrocytes Protect Against Copper-Catalysed Loss of Extracellular Glutathione

(2008) Simon A. S. Pope et al.   NEUROCHEMICAL RESEARCH

The NMDA antagonist MK-801 induces hyperalgesia and increases CSF excitatory amino acids in rats: Reversal by guanosine

(2008) André P. Schmidt et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: Involvement of oxidative stress and glutamatergic system

(2008) Daniel H. Roos et al.   TOXICOLOGY IN VITRO

The undertow of sulfur metabolism on glutamatergic neurotransmission

(2008) Ruma Banerjee et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen–glucose deprivation

(2007) Scheyla P.B. Oleskovicz et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroprotective effects of guanosine on stroke models in vitro and in vivo

(2007) Ruby Chang et al.   NEUROSCIENCE LETTERS