Calcium homeostasis modulator (CALHM) ion channels

The CALHM1 P86L Polymorphism is a Genetic Modifier of Age at Onset in Alzheimer's Disease: a Meta-Analysis Study

(2017) Jean-Charles Lambert et al.   JOURNAL OF ALZHEIMERS DISEASE

Mice Lacking Pannexin 1 Release ATP and Respond Normally to All Taste Qualities

(2015) Aurelie Vandenbeuch et al.   CHEMICAL SENSES

Normal Taste Acceptance and Preference of PANX1 Knockout Mice

(2015) Michael G. Tordoff et al.   CHEMICAL SENSES

CALHM1 ion channel elicits amyloid-  clearance by insulin-degrading enzyme in cell lines and in vivo in the mouse brain

(2015) V. Vingtdeux et al.   JOURNAL OF CELL SCIENCE

SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel

(2014) Zhaozhu Qiu et al.   CELL

Effect of the CALHM1 G330D and R154H Human Variants on the Control of Cytosolic Ca2+ and Aβ Levels

(2014) Valérie Vingtdeux et al.   PLoS One

Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC

(2014) F. K. Voss et al.   SCIENCE

Motifs in the permeation pathway of connexin channels mediate voltage and Ca2+ sensing

(2014) Andrew L. Harris et al.   Frontiers in Physiology

How do taste cells lacking synapses mediate neurotransmission? CALHM1, a voltage-gated ATP channel

(2013) Akiyuki Taruno et al.   BIOESSAYS

Structural and Functional Similarities of Calcium Homeostasis Modulator 1 (CALHM1) Ion Channel with Connexins, Pannexins, and Innexins

(2013) Adam P. Siebert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CALHM1 controls the Ca2+-dependent MEK, ERK, RSK and MSK signaling cascade in neurons

(2013) U. Dreses-Werringloer et al.   JOURNAL OF CELL SCIENCE

Insights on the mechanisms of Ca2+regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y)

(2013) William Lopez et al.   JOURNAL OF GENERAL PHYSIOLOGY

The D50N mutation and syndromic deafness: Altered Cx26 hemichannel properties caused by effects on the pore and intersubunit interactions

(2013) Helmuth A. Sanchez et al.   JOURNAL OF GENERAL PHYSIOLOGY

CLHM-1 is a Functionally Conserved and Conditionally Toxic Ca2+-Permeable Ion Channel in Caenorhabditis elegans

(2013) J. E. Tanis et al.   JOURNAL OF NEUROSCIENCE

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

(2013) Akiyuki Taruno et al.   NATURE

Rare Variants in Calcium Homeostasis Modulator 1 (CALHM1) Found in Early Onset Alzheimer’s Disease Patients Alter Calcium Homeostasis

(2013) Fanny Rubio-Moscardo et al.   PLoS One

A taste for ATP: neurotransmission in taste buds

(2013) Sue C. Kinnamon et al.   Frontiers in Cellular Neuroscience

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability

(2012) Z. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Calcium Release-Activated Calcium Channel Orai

(2012) X. Hou et al.   SCIENCE

Functional diversification of taste cells in vertebrates

(2012) Ichiro Matsumoto et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress

(2011) Sonia Gallego-Sandín et al.   BIOCHEMICAL JOURNAL

Skn-1a (Pou2f3) specifies taste receptor cell lineage

(2011) Ichiro Matsumoto et al.   NATURE NEUROSCIENCE

The cell biology of taste

(2010) Nirupa Chaudhari et al.   JOURNAL OF CELL BIOLOGY

SCAM analysis of Panx1 suggests a peculiar pore structure

(2010) Junjie Wang et al.   JOURNAL OF GENERAL PHYSIOLOGY

The cells and peripheral representation of sodium taste in mice

(2010) Jayaram Chandrashekar et al.   NATURE

CALHM1Polymorphism is not Associated with Late-onset Alzheimer Disease

(2009) Gary W. Beecham et al.   ANNALS OF HUMAN GENETICS

Common Sense about Taste: From Mammals to Insects

(2009) David A. Yarmolinsky et al.   CELL

No association betweenCALHM1variation and risk of Alzheimer disease

(2009) Ryan L. Minster et al.   HUMAN MUTATION

Structure of the connexin 26 gap junction channel at 3.5 Å resolution

(2009) Shoji Maeda et al.   NATURE

Expression of Genes Encoding Multi-Transmembrane Proteins in Specific Primate Taste Cell Populations

(2009) Bryan D. Moyer et al.   PLoS One

Structural determinants of ion permeation in CRAC channels

(2009) Beth A. McNally et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

No Association between CALHM1 and Alzheimer's Disease Risk

(2008) Lars Bertram et al.   CELL

A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

(2008) Ute Dreses-Werringloer et al.   CELL