How do taste cells lacking synapses mediate neurotransmission? CALHM1, a voltage-gated ATP channel

Structural and Functional Similarities of Calcium Homeostasis Modulator 1 (CALHM1) Ion Channel with Connexins, Pannexins, and Innexins

(2013) Adam P. Siebert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hearing Is Normal without Connexin30

(2013) A.-C. Boulay et al.   JOURNAL OF NEUROSCIENCE

High salt recruits aversive taste pathways

(2013) Yuki Oka et al.   NATURE

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

(2013) Akiyuki Taruno et al.   NATURE

Astrocytic Cx43 and Cx30 differentially modulate adult neurogenesis in mice

(2013) Marie Liebmann et al.   NEUROSCIENCE LETTERS

Purinergic signalling: Its unpopular beginning, its acceptance and its exciting future

(2012) Geoffrey Burnstock   BIOESSAYS

The ATP permeability of pannexin 1 channels in a heterologous system and in mammalian taste cells is dispensable

(2012) Roman A. Romanov et al.   JOURNAL OF CELL SCIENCE

Gap26, a connexin mimetic peptide, inhibits currents carried by connexin43 hemichannels and gap junction channels

(2012) T. Desplantez et al.   PHARMACOLOGICAL RESEARCH

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability

(2012) Z. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Taste buds as peripheral chemosensory processors

(2012) Stephen D. Roper   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Functional diversification of taste cells in vertebrates

(2012) Ichiro Matsumoto et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Generation of Calhm1 knockout mouse and characterization of calhm1 gene expression

(2012) Junbing Wu et al.   Protein & Cell

Pannexin channels are not gap junction hemichannels

(2011) Gina E. Sosinsky et al.   Channels

Rho Signaling Regulates Pannexin 1-mediated ATP Release from Airway Epithelia

(2011) Lucia Seminario-Vidal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow

(2011) Ang Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Knocking Out P2X Receptors Reduces Transmitter Secretion in Taste Buds

(2011) Y. A. Huang et al.   JOURNAL OF NEUROSCIENCE

Skn-1a (Pou2f3) specifies taste receptor cell lineage

(2011) Ichiro Matsumoto et al.   NATURE NEUROSCIENCE

Probenecid Inhibits the Human Bitter Taste Receptor TAS2R16 and Suppresses Bitter Perception of Salicin

(2011) Tiffani A. Greene et al.   PLoS One

Carbenoxolone inhibits volume-regulated anion conductance in cultured rat cortical astroglia

(2010) Valentina Benfenati et al.   Channels

The cell biology of taste

(2010) Nirupa Chaudhari et al.   JOURNAL OF CELL BIOLOGY

Action Potential–Enhanced ATP Release From Taste Cells Through Hemichannels

(2010) Yoshihiro Murata et al.   JOURNAL OF NEUROPHYSIOLOGY

Capacitance Measurements of Regulated Exocytosis in Mouse Taste Cells

(2010) A. Vandenbeuch et al.   JOURNAL OF NEUROSCIENCE

Intracellular Ca2+and TRPM5-mediated membrane depolarization produce ATP secretion from taste receptor cells

(2010) Yijen A. Huang et al.   JOURNAL OF PHYSIOLOGY-LONDON

The cells and peripheral representation of sodium taste in mice

(2010) Jayaram Chandrashekar et al.   NATURE

Identification of the vesicular nucleotide transporter (VNUT) in taste cells

(2009) Ken Iwatsuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Voltage-gated sodium channels in taste bud cells

(2009) Na Gao et al.   BMC NEUROSCIENCE

Common Sense about Taste: From Mammals to Insects

(2009) David A. Yarmolinsky et al.   CELL

Direct Actions of Carbenoxolone on Synaptic Transmission and Neuronal Membrane Properties

(2009) Kenneth R. Tovar et al.   JOURNAL OF NEUROPHYSIOLOGY

Cell-to-cell communication in intact taste buds through ATP signalling from pannexin 1 gap junction hemichannels

(2009) Robin Dando et al.   JOURNAL OF PHYSIOLOGY-LONDON

Expression of Genes Encoding Multi-Transmembrane Proteins in Specific Primate Taste Cell Populations

(2009) Bryan D. Moyer et al.   PLoS One

Probenecid, a gout remedy, inhibits pannexin 1 channels

(2008) William Silverman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

(2008) Ute Dreses-Werringloer et al.   CELL

Pharmacokinetic and Pharmacodynamic Interaction between Allopurinol and Probenecid??in Healthy Subjects

(2008) Sophie L Stocker et al.   CLINICAL PHARMACOKINETICS

Voltage Dependence of ATP Secretion in Mammalian Taste Cells

(2008) Roman A. Romanov et al.   JOURNAL OF GENERAL PHYSIOLOGY

Divalent Cations Regulate Connexin Hemichannels by Modulating Intrinsic Voltage-dependent Gating

(2008) Vytas K. Verselis et al.   JOURNAL OF GENERAL PHYSIOLOGY

Connexin 43 Hemichannels Are Permeable to ATP

(2008) J. Kang et al.   JOURNAL OF NEUROSCIENCE

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear

(2008) F. Anselmi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA