Rare Variants in Calcium Homeostasis Modulator 1 (CALHM1) Found in Early Onset Alzheimer’s Disease Patients Alter Calcium Homeostasis

Familial Alzheimer's Disease Mutations in Presenilins: Effects on Endoplasmic Reticulum Calcium Homeostasis and Correlation with Clinical Phenotypes

(2017) Omar Nelson et al.   JOURNAL OF ALZHEIMERS DISEASE

The CALHM1 P86L Polymorphism is a Genetic Modifier of Age at Onset in Alzheimer's Disease: a Meta-Analysis Study

(2017) Jean-Charles Lambert et al.   JOURNAL OF ALZHEIMERS DISEASE

CALHM1 P86L Polymorphism is Associated with Late-Onset Alzheimer's Disease in a Recessive Model

(2017) Mercè Boada et al.   JOURNAL OF ALZHEIMERS DISEASE

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability

(2012) Z. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synapses and Alzheimer's Disease

(2012) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress

(2011) Sonia Gallego-Sandín et al.   BIOCHEMICAL JOURNAL

Impaired regulation of synaptic actin cytoskeleton in Alzheimer's disease

(2011) Peter Penzes et al.   BRAIN RESEARCH REVIEWS

Presenilins function in ER calcium leak and Alzheimer's disease pathogenesis

(2011) Charlene Supnet et al.   CELL CALCIUM

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

ER Calcium and Alzheimer's Disease: In a State of Flux

(2010) M. P. Mattson   Science Signaling

Mitochondria sense with different kinetics the calcium entering into HeLa cells through calcium channels CALHM1 and mutated P86L-CALHM1

(2009) Ana J. Moreno-Ortega et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

No association betweenCALHM1and risk for Alzheimer dementia in a Belgian population

(2009) Kristel Sleegers et al.   HUMAN MUTATION

No association betweenCALHM1variation and risk of Alzheimer disease

(2009) Ryan L. Minster et al.   HUMAN MUTATION

Mild cholesterol depletion reduces amyloid-β production by impairing APP trafficking to the cell surface

(2009) Cristina Guardia-Laguarta et al.   JOURNAL OF NEUROCHEMISTRY

No Association between CALHM1 and Alzheimer's Disease Risk

(2008) Lars Bertram et al.   CELL

A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

(2008) Ute Dreses-Werringloer et al.   CELL

IP3sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5′-6′-epoxyeicosatrienoic acid

(2008) Jacqueline Fernandes et al.   JOURNAL OF CELL BIOLOGY

Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP

(2008) Rita Joao Guerreiro et al.   NEUROBIOLOGY OF AGING

Calcium Channel Regulation and Presynaptic Plasticity

(2008) William A. Catterall et al.   NEURON

Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating

(2008) King-Ho Cheung et al.   NEURON

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON

Oxidative stress triggers the amyloidogenic pathway in human vascular smooth muscle cells

(2007) Mireia Coma et al.   NEUROBIOLOGY OF AGING