Intercellular Adhesion Molecule 1 Engagement Modulates Sphingomyelinase and Ceramide, Supporting Uptake of Drug Carriers by the Vascular Endothelium

Src Phosphorylation of Endothelial Cell Surface Intercellular Adhesion Molecule-1 Mediates Neutrophil Adhesion and Contributes to the Mechanism of Lung Inflammation

(2011) Guoquan Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Acid Sphingomyelinase Deficiency Attenuates Bleomycin-Induced Lung Inflammation and Fibrosis in Mice

(2010) Rajwinder Dhami et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Differential Effects of Ceramide and Sphingosine 1-Phosphate on ERM Phosphorylation

(2010) Daniel Canals et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair

(2010) Christina Tam et al.   JOURNAL OF CELL BIOLOGY

Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease

(2010) Janet Hsu et al.   JOURNAL OF CONTROLLED RELEASE

Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers

(2010) Andres J. Calderon et al.   JOURNAL OF CONTROLLED RELEASE

Roles and regulation of secretory and lysosomal acid sphingomyelinase

(2009) Russell W. Jenkins et al.   CELLULAR SIGNALLING

Acid sphingomyelinase, cell membranes and human disease: Lessons from Niemann-Pick disease

(2009) Edward H. Schuchman   FEBS LETTERS

Acid Sphingomyelinase Promotes Lipoprotein Retention Within Early Atheromata and Accelerates Lesion Progression

(2008) Cecilia M. Devlin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Altered Shear Stress Stimulates Upregulation of Endothelial VCAM-1 and ICAM-1 in a BMP-4– and TGF-β1–Dependent Pathway

(2008) Philippe Sucosky et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway

(2008) Youssef H. Zeidan et al.   JOURNAL OF CELL BIOLOGY

Delivery of Acid Sphingomyelinase in Normal and Niemann-Pick Disease Mice Using Intercellular Adhesion Molecule-1-Targeted Polymer Nanocarriers

(2008) C. Garnacho et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers

(2008) Silvia Muro et al.   MOLECULAR THERAPY

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

(2008) Volker Teichgräber et al.   NATURE MEDICINE

Critical Role of Lipid Raft Redox Signaling Platforms in Endostatin-Induced Coronary Endothelial Dysfunction

(2007) Si Jin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY