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Genetic Engineering of a Bifunctional IgG Fusion Protein with Iduronate-2-Sulfatase

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AGT-181: Expression in CHO cells and pharmacokinetics, safety, and plasma iduronidase enzyme activity in Rhesus monkeys

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Pharmacokinetics and Brain Uptake of a Genetically Engineered Bifunctional Fusion Antibody Targeting the Mouse Transferrin Receptor

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Re-Engineering Biopharmaceuticals for Delivery to Brain with Molecular Trojan Horses

(2008) William M. Pardridge   BIOCONJUGATE CHEMISTRY

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