Immune cell subset differentiation and tissue inflammation

Mechanisms of resistance to immune checkpoint inhibitors

(2018) Russell W Jenkins et al.   BRITISH JOURNAL OF CANCER

Myeloid derived-suppressor cells: their role in cancer and obesity

(2018) Suzanne Ostrand-Rosenberg   CURRENT OPINION IN IMMUNOLOGY

moDCs, Less Problems

(2018) Alycia Gardner et al.   IMMUNITY

TCR tuning of T cell subsets

(2018) Jae-Ho Cho et al.   IMMUNOLOGICAL REVIEWS

Alternative macrophages in atherosclerosis: not always protective!

(2018) Benoit Pourcet et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolism-associated danger signal-induced immune response and reverse immune checkpoint-activated CD40+ monocyte differentiation

(2017) Jin Dai et al.   Journal of Hematology & Oncology

Is CD47 an innate immune checkpoint for tumor evasion?

(2017) Xiaojuan Liu et al.   Journal of Hematology & Oncology

Tumor-associated macrophages: from basic research to clinical application

(2017) Li Yang et al.   Journal of Hematology & Oncology

Checkpoint inhibitors in hematological malignancies

(2017) Chi Young Ok et al.   Journal of Hematology & Oncology

Increased frequency of peripheral blood follicular helper T cells and elevated serum IL-21 levels in patients with knee osteoarthritis

(2017) Yuxing Shan et al.   Molecular Medicine Reports

Current Understanding in Neutrophil Differentiation and Heterogeneity

(2017) Chang-Won Hong   Immune Network

Phenotype, function, and differentiation potential of human monocyte subsets

(2017) Lisa B. Boyette et al.   PLoS One

Transcriptional Control of Dendritic Cell Development

(2016) Theresa L. Murphy et al.   Annual Review of Immunology

2014 Jeffrey M. Hoeg Award Lecture

(2016) Yanfang Peipei Zhu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell ActivationHighlights

(2016) Xinyuan Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mast cell differentiation: still open questions?

(2016) M. Arock   BLOOD

CD11b+Gr-1+myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mice

(2016) Amanda C. Foks et al.   CARDIOVASCULAR RESEARCH

Chronic Kidney Disease Induces Inflammatory CD40 + Monocyte Differentiation via Homocysteine Elevation and DNA HypomethylationNovelty and Significance

(2016) Jiyeon Yang et al.   CIRCULATION RESEARCH

The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells

(2016) Shinelle Menezes et al.   IMMUNITY

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Lin- CD34hi CD117int/hi Fc RI+ cells in human blood constitute a rare population of mast cell progenitors

(2015) J. S. Dahlin et al.   BLOOD

Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque MotilityCLINICAL PERSPECTIVE

(2015) Indira Medina et al.   CIRCULATION

B-1b Cells Secrete Atheroprotective IgM and Attenuate AtherosclerosisNovelty and Significance

(2015) Sam M. Rosenfeld et al.   CIRCULATION RESEARCH

CD8+T Cells Regulate Monopoiesis and Circulating Ly6ChighMonocyte Levels in Atherosclerosis in MiceNovelty and Significance

(2015) Clément Cochain et al.   CIRCULATION RESEARCH

Interleukin-6 as a Therapeutic Target

(2015) J.-F. Rossi et al.   CLINICAL CANCER RESEARCH

Regulation of human helper T cell subset differentiation by cytokines

(2015) Nathalie Schmitt et al.   CURRENT OPINION IN IMMUNOLOGY

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

Converting smooth muscle cells to macrophage-like cells with KLF4 in atherosclerotic plaques

(2015) Michael E Rosenfeld   NATURE MEDICINE

Non-Classical monocytes display inflammatory features: Validation in Sepsis and Systemic Lupus Erythematous

(2015) Ratnadeep Mukherjee et al.   Scientific Reports

Association of Elevations of Specific T Cell and Monocyte Subpopulations in Rheumatoid Arthritis With Subclinical Coronary Artery Atherosclerosis

(2015) Robert Winchester et al.   Arthritis & Rheumatology

Expression of monocyte subsets and angiogenic markers in relation to carotid plaque neovascularization in patients with pre-existing coronary artery disease and carotid stenosis

(2014) Anthony S. Jaipersad et al.   ANNALS OF MEDICINE

Association of plasma PCSK9 levels with white blood cell count and its subsets in patients with stable coronary artery disease

(2014) Sha Li et al.   ATHEROSCLEROSIS

Artery Tertiary Lymphoid Organs Contribute to Innate and Adaptive Immune Responses in Advanced Mouse Atherosclerosis

(2014) Sarajo Kumar Mohanta et al.   CIRCULATION RESEARCH

Hyperhomocysteinemia Potentiates Hyperglycemia-Induced Inflammatory Monocyte Differentiation and Atherosclerosis

(2014) P. Fang et al.   DIABETES

Circulating CD3+56+ Cell Subset in Pre-diabetes

(2014) M. Dworacka et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Targeted depletion of an MDSC subset unmasks pancreatic ductal adenocarcinoma to adaptive immunity

(2014) Ingunn M Stromnes et al.   GUT

Development and Function of Dendritic Cell Subsets

(2014) Alexander Mildner et al.   IMMUNITY

B7-H1–expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets

(2014) Dong-Ming Kuang et al.   JOURNAL OF CLINICAL INVESTIGATION

Kruppel-Like Factor 4 Is Essential for Inflammatory Monocyte Differentiation In Vivo

(2014) J. K. Alder et al.   JOURNAL OF IMMUNOLOGY

Modulation of TNF-Induced Macrophage Polarization by Synovial Fibroblasts

(2014) Laura T. Donlin et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cell Subset Distributions in the Aorta in Healthy and Atherosclerotic Mice

(2014) Martin Busch et al.   PLoS One

Regulatory T Cells in B Cell Follicles

(2014) Jae-Hoon Chang et al.   Immune Network

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

MicroRNAs in Immune Response and Macrophage Polarization

(2013) Gang Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Expansion of the NKG2C+ Natural Killer–Cell Subset Is Associated With High-Risk Carotid Atherosclerotic Plaques in Seropositive Patients for Human Cytomegalovirus

(2013) Jose Enrique Martínez-Rodríguez et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

(2013) D. Kurotaki et al.   BLOOD

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

Hematopoiesis

(2013) M. Jagannathan-Bogdan et al.   DEVELOPMENT

Sources of heterogeneity in human monocyte subsets

(2013) Laura J. Appleby et al.   IMMUNOLOGY LETTERS

TLR4 expression on monocyte subsets in myocardial infarction

(2013) L. D. Tapp et al.   JOURNAL OF INTERNAL MEDICINE

Increased proatherogenic monocyte-platelet cross-talk in monocyte subpopulations of patients with stable coronary artery disease

(2013) F. S. Czepluch et al.   JOURNAL OF INTERNAL MEDICINE

Discrete functions of M 2a and M 2c macrophage subsets determine their relative efficacy in treating chronic kidney disease

(2013) Junyu Lu et al.   KIDNEY INTERNATIONAL

Origin of monocytes and macrophages in a committed progenitor

(2013) Jan Hettinger et al.   NATURE IMMUNOLOGY

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation

(2013) Bryan Vander Lugt et al.   NATURE IMMUNOLOGY

Circadian Gene Bmal1 Regulates Diurnal Oscillations of Ly6Chi Inflammatory Monocytes

(2013) K. D. Nguyen et al.   SCIENCE

Myeloid Krüppel-Like Factor 4 Deficiency Augments Atherogenesis in ApoE −/− Mice—Brief Report

(2012) Nikunj Sharma et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

Revisiting the B-cell compartment in mouse and humans: more than one B-cell subset exists in the marginal zone and beyond

(2012) Olivier Garraud et al.   BMC IMMUNOLOGY

Interleukin-6 signaling pathway in targeted therapy for cancer

(2012) Yuqi Guo et al.   CANCER TREATMENT REVIEWS

Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis

(2012) Dirk Lievens et al.   EUROPEAN HEART JOURNAL

Human Th17 subsets

(2012) Federica Sallusto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective Role for TLR4 Signaling in Atherosclerosis Progression as Revealed by Infection with a Common Oral Pathogen

(2012) C. Hayashi et al.   JOURNAL OF IMMUNOLOGY

IRF4 Promotes Cutaneous Dendritic Cell Migration to Lymph Nodes during Homeostasis and Inflammation

(2012) S. Bajana et al.   JOURNAL OF IMMUNOLOGY

Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice

(2012) Marjo M. P. C. Donners et al.   PLoS One

Effector Memory T cells Are Associated With Atherosclerosis in Humans and Animal Models

(2012) Enrico Ammirati et al.   Journal of the American Heart Association

Phenotypic and Functional Heterogeneity of Macrophages and Dendritic Cell Subsets in the Healthy and Atherosclerosis-Prone Aorta

(2012) Matthew J. Butcher et al.   Frontiers in Physiology

Plasmacytoid Dendritic Cells: Recent Progress and Open Questions

(2011) Boris Reizis et al.   Annual Review of Immunology

CD14 dim CD16 + and CD14 + CD16 + Monocytes in Obesity and During Weight Loss

(2011) Christine Poitou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Class A scavenger receptor attenuates myocardial infarction-induced cardiomyocyte necrosis through suppressing M1 macrophage subset polarization

(2011) Yulong Hu et al.   BASIC RESEARCH IN CARDIOLOGY

Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung

(2011) Zvi Granot et al.   CANCER CELL

Activating Transcription Factor 1 Directs Mhem Atheroprotective Macrophages Through Coordinated Iron Handling and Foam Cell Protection

(2011) Joseph J. Boyle et al.   CIRCULATION RESEARCH

Eosinophil count is positively correlated with coronary artery calcification

(2011) Muhei Tanaka et al.   HYPERTENSION RESEARCH

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

Notch2 Receptor Signaling Controls Functional Differentiation of Dendritic Cells in the Spleen and Intestine

(2011) Kanako L. Lewis et al.   IMMUNITY

Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease

(2011) Robert C. Rickert et al.   IMMUNOLOGICAL REVIEWS

Krüppel-like factor 4 regulates macrophage polarization

(2011) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

Accelerated Dendritic Cell Differentiation from Migrating Ly6Clo Bone Marrow Monocytes in Early Dermal West Nile Virus Infection

(2011) A. M. Davison et al.   JOURNAL OF IMMUNOLOGY

Macrophage Differentiation and Polarization via Phosphatidylinositol 3-Kinase/Akt-ERK Signaling Pathway Conferred by Serum Amyloid P Component

(2011) W. Zhang et al.   JOURNAL OF IMMUNOLOGY

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes

(2011) Richard N Hanna et al.   NATURE IMMUNOLOGY

High Neutrophil Numbers in Human Carotid Atherosclerotic Plaques Are Associated With Characteristics of Rupture-Prone Lesions

(2010) Mihaela G. Ionita et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Association of monocyte subset counts with coronary fibrous cap thickness in patients with unstable angina pectoris

(2010) Toshio Imanishi et al.   ATHEROSCLEROSIS

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

IL-6: Regulator of Treg/Th17 balance

(2010) Akihiro Kimura et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Continuous Expression of the Transcription Factor E2-2 Maintains the Cell Fate of Mature Plasmacytoid Dendritic Cells

(2010) Hiyaa S. Ghosh et al.   IMMUNITY

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

(2010) Jérôme Cros et al.   IMMUNITY

Origin and functional heterogeneity of non-lymphoid tissue dendritic cells in mice

(2010) Julie Helft et al.   IMMUNOLOGICAL REVIEWS

The CD8+dendritic cell subset

(2010) Ken Shortman et al.   IMMUNOLOGICAL REVIEWS

Blockade of Notch1 Signaling Alleviates Murine Lupus via Blunting Macrophage Activation and M2b Polarization

(2010) W. Zhang et al.   JOURNAL OF IMMUNOLOGY

CXC Chemokine Ligand 4 Induces a Unique Transcriptome in Monocyte-Derived Macrophages

(2010) C. A. Gleissner et al.   JOURNAL OF IMMUNOLOGY

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Coronary Intraplaque Hemorrhage Evokes a Novel Atheroprotective Macrophage Phenotype

(2009) Joseph J. Boyle et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanisms underlying neutrophil-mediated monocyte recruitment

(2009) O. Soehnlein et al.   BLOOD

Monocytes: subsets, origins, fates and functions

(2009) Simon Yona et al.   CURRENT OPINION IN HEMATOLOGY

Obesity predisposes to Th17 bias

(2009) Shawn Winer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The origin and development of nonlymphoid tissue CD103+DCs

(2009) Florent Ginhoux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

(2009) Kylie E. Webster et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Signal transduction and Th17 cell differentiation

(2009) John J. O'Shea et al.   MICROBES AND INFECTION

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

Class-switched B cells display response to therapeutic B cell depletion in rheumatoid arthritis

(2009) Burkhard Moller et al.   ARTHRITIS RESEARCH & THERAPY

iNOS-Producing Inflammatory Dendritic Cells Constitute the Major Infected Cell Type during the Chronic Leishmania major Infection Phase of C57BL/6 Resistant Mice

(2009) Carl De Trez et al.   PLoS Pathogens

Leukocyte Activation by Triglyceride-Rich Lipoproteins

(2008) Arash Alipour et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

(2008) Babacar Cisse et al.   CELL

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

Peripheral B cell subsets

(2008) David Allman et al.   CURRENT OPINION IN IMMUNOLOGY

Foxp3 Inhibits RORγt-mediatedIL-17AmRNA Transcription through Direct Interaction with RORγt

(2008) Kenji Ichiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE

Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues

(2008) L. M. Wakim et al.   SCIENCE

Macrophages, PPARs, and Cancer

(2008) Jo A. Van Ginderachter et al.   PPAR Research

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

(2008) Scott H Robbins et al.   GENOME BIOLOGY

Predictive value of white blood cell subtypes for long-term outcome following myocardial infarction

(2006) Robert Dragu et al.   ATHEROSCLEROSIS