Codon pair bias deoptimization of the major oncogene meq of a very virulent Marek’s disease virus

Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models

(2018) Penghui Li et al.   JOURNAL OF VIROLOGY

Attenuation of Marek's disease virus by codon pair deoptimization of a core gene

(2018) Steven J. Conrad et al.   VIROLOGY

Attenuation of a very virulent Marek's disease herpesvirus (MDV) by codon pair bias deoptimization

(2018) Kathrin Eschke et al.   PLoS Pathogens

A phylogenomic analysis of Marek's disease virus reveals independent paths to virulence in Eurasia and North America

(2017) Jakob Trimpert et al.   Evolutionary Applications

Marek’s disease vaccines: Current status, and strategies for improvement and development of vector vaccines

(2017) Sanjay M. Reddy et al.   VETERINARY MICROBIOLOGY

Evaluation of the attenuation, immunogenicity, and efficacy of a live virus vaccine generated by codon-pair bias de-optimization of the 2009 pandemic H1N1 influenza virus, in ferrets

(2016) Andrew J. Broadbent et al.   VACCINE

Codon Pair Bias Is a Direct Consequence of Dinucleotide Bias

(2016) Dusan Kunec et al.   Cell Reports

Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference

(2015) Sam H. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recoding of the Vesicular Stomatitis Virus L Gene by Computer-Aided Design Provides a Live, Attenuated Vaccine Candidate

(2015) Bingyin Wang et al.   mBio

Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens

(2015) Andrew F. Read et al.   PLOS BIOLOGY

Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization

(2014) C. Le Nouen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computer-aided codon-pairs deoptimization of the major envelope GP5 gene attenuates porcine reproductive and respiratory syndrome virus

(2014) Yan-Yan Ni et al.   VIROLOGY

RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies

(2014) Fiona Tulloch et al.   eLife

Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice

(2013) Chen Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture

(2013) Gloria Martrus et al.   Retrovirology

Marek's Disease Virus Late Protein Expression in Feather Follicle Epithelial Cells as Early as 8 Days Postinfection

(2012) Keith W. Jarosinski   AVIAN DISEASES

Marek's Disease Viral Interleukin-8 Promotes Lymphoma Formation through Targeted Recruitment of B Cells and CD4+CD25+T Cells

(2012) Annemarie T. Engel et al.   JOURNAL OF VIROLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Live attenuated influenza virus vaccines by computer-aided rational design

(2010) Steffen Mueller et al.   NATURE BIOTECHNOLOGY

In vitro characterization of the Meq proteins of Marek's disease virus vaccine strain CVI988

(2009) Dharani K. Ajithdoss et al.   VIRUS RESEARCH

Virus Attenuation by Genome-Scale Changes in Codon Pair Bias

(2008) J. R. Coleman et al.   SCIENCE

Marek's disease vaccines: A solution for today but a worry for tomorrow?

(2008) Isabel M. Gimeno   VACCINE