Attenuation of a very virulent Marek's disease herpesvirus (MDV) by codon pair bias deoptimization

A phylogenomic analysis of Marek's disease virus reveals independent paths to virulence in Eurasia and North America

(2017) Jakob Trimpert et al.   Evolutionary Applications

The Short Form of the Zinc Finger Antiviral Protein Inhibits Influenza A Virus Protein Expression and Is Antagonized by the Virus-Encoded NS1

(2016) Qiannan Tang et al.   JOURNAL OF VIROLOGY

Evaluation of the attenuation, immunogenicity, and efficacy of a live virus vaccine generated by codon-pair bias de-optimization of the 2009 pandemic H1N1 influenza virus, in ferrets

(2016) Andrew J. Broadbent et al.   VACCINE

Codon Pair Bias Is a Direct Consequence of Dinucleotide Bias

(2016) Dusan Kunec et al.   Cell Reports

Battle between influenza A virus and a newly identified antiviral activity of the PARP-containing ZAPL protein

(2015) Chien-Hung Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recoding of the Vesicular Stomatitis Virus L Gene by Computer-Aided Design Provides a Live, Attenuated Vaccine Candidate

(2015) Bingyin Wang et al.   mBio

Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens

(2015) Andrew F. Read et al.   PLOS BIOLOGY

Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization

(2014) C. Le Nouen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice

(2013) Chen Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture

(2013) Gloria Martrus et al.   Retrovirology

Live attenuated influenza virus vaccines by computer-aided rational design

(2010) Steffen Mueller et al.   NATURE BIOTECHNOLOGY

Synthetic viruses: a new opportunity to understand and prevent viral disease

(2009) Eckard Wimmer et al.   NATURE BIOTECHNOLOGY

Patterns of Oligonucleotide Sequences in Viral and Host Cell RNA Identify Mediators of the Host Innate Immune System

(2009) Benjamin D. Greenbaum et al.   PLoS One

Virus Attenuation by Genome-Scale Changes in Codon Pair Bias

(2008) J. R. Coleman et al.   SCIENCE

Marek's disease vaccines: A solution for today but a worry for tomorrow?

(2008) Isabel M. Gimeno   VACCINE