Friend or Foe? The Current Epidemiologic Evidence on Selenium and Human Cancer Risk

Toward Understanding Success and Failures in the Use of Selenium for Cancer Prevention

(2013) Holger Steinbrenner et al.   ANTIOXIDANTS & REDOX SIGNALING

Characterization of cytosolic glutathione peroxidase and phospholipid-hydroperoxide glutathione peroxidase genes in rainbow trout (Oncorhynchus mykiss) and their modulation by in vitro selenium exposure

(2013) D. Pacitti et al.   AQUATIC TOXICOLOGY

Anex vivostudy of selenium, genistein on the morphological and nuclear changes in anticancer drug-induced apoptosis in human peripheral blood lymphocytes

(2013) Elango Sonaa et al.   BIOFACTORS

Long-Term Selenium Supplementation in HaCaT Cells: Importance of Chemical Form for Antagonist (Protective Versus Toxic) Activities

(2013) Florence Hazane-Puch et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Selective cellular uptake and induction of apoptosis of cancer-targeted selenium nanoparticles

(2013) Yanyu Huang et al.   BIOMATERIALS

Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity

(2013) Edson dos A. dos Santos et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Influence of concurrent medications on outcomes of men with prostate cancer included in the TAX 327 study

(2013) Saroj Niraula et al.   CUAJ-Canadian Urological Association Journal

A Cross-sectional Study of the Impact of Blood Selenium on Blood and Urinary Arsenic Concentrations in Bangladesh

(2013) Christine Marie George et al.   Environmental Health

The link between selenium binding protein from Sinonovacula constricta and environmental pollutions exposure

(2013) Yali Lu et al.   FISH & SHELLFISH IMMUNOLOGY

Dietary selenium supplementation modifies breast tumor growth and metastasis

(2013) Yu-Chi Chen et al.   INTERNATIONAL JOURNAL OF CANCER

Comparative oral dose toxicokinetics of selenium compounds commonly found in selenium accumulator plants1

(2013) T. Z. Davis et al.   JOURNAL OF ANIMAL SCIENCE

The Properties, Functions, and Use of Selenium Compounds in Living Organisms

(2013) MALGORZATA BODNAR et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Cerebrospinal fluid of newly diagnosed amyotrophic lateral sclerosis patients exhibits abnormal levels of selenium species including elevated selenite

(2013) Marco Vinceti et al.   NEUROTOXICOLOGY

Selenium intake and selenium blood levels: a novel food frequency questionnaire

(2013) Marianne Pestitschek et al.   WIENER KLINISCHE WOCHENSCHRIFT

RhoA modulates functional and physical interaction between ROCK1 and Erk1/2 in selenite-induced apoptosis of leukaemia cells

(2013) F Li et al.   Cell Death & Disease

Selenium Metabolism in Cancer Cells: The Combined Application of XAS and XFM Techniques to the Problem of Selenium Speciation in Biological Systems

(2013) Claire Weekley et al.   Nutrients

Selenium and prostate cancer: systematic review and meta-analysis

(2012) Rachel Hurst et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Selenium speciation in paired serum and cerebrospinal fluid samples

(2012) Nikolay Solovyev et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Lessons Learned from Randomized Clinical Trials of Micronutrient Supplementation for Cancer Prevention

(2012) Susan T. Mayne et al.   Annual Review of Nutrition

Selenate inhibits adipogenesis through induction of transforming growth factor-β1 (TGF-β1) signaling

(2012) Choon Young Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition

(2012) Sreenivasulu Chintala et al.   BMC CANCER

Effects of Smoking and Antioxidant Micronutrients on Risk of Colorectal Cancer

(2012) Rikke Dalgaard Hansen et al.   Clinical Gastroenterology and Hepatology

Moving a randomized clinical trial into an observational cohort

(2012) Phyllis J Goodman et al.   Clinical Trials

Subacute toxicity of nano-selenium compared to other selenium species in mice

(2012) Ilona Benko et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Influence of serum selenium concentrations on hypertension

(2012) Heiner K. Berthold et al.   JOURNAL OF HYPERTENSION

The catalytic subunit of DNA-dependent protein kinase is downstream of ATM and feeds forward oxidative stress in the selenium-induced senescence response

(2012) Caroline R.B. Rocourt et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Do Dietary Supplements Have Beneficial Health Effects in Industrialized Nations

(2012) Paul E. Marik et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Evaluation of Vitamin E and Selenium Supplementation for the Prevention of Bladder Cancer in SWOG Coordinated SELECT

(2012) Yair Lotan et al.   JOURNAL OF UROLOGY

Simultaneous Targeting of COX-2 and AKT Using Selenocoxib-1-GSH to Inhibit Melanoma

(2012) R. Gowda et al.   MOLECULAR CANCER THERAPEUTICS

The influence of selenium and selenoprotein gene variants on colorectal cancer risk

(2012) C. Meplan et al.   MUTAGENESIS

Methylseleninic Acid Enhances Paclitaxel Efficacy for the Treatment of Triple-Negative Breast Cancer

(2012) Yanfeng Qi et al.   PLoS One

Rational Incorporation of Selenium into Temozolomide Elicits Superior Antitumor Activity Associated with Both Apoptotic and Autophagic Cell Death

(2012) Yan Cheng et al.   PLoS One

Genetic Variation in Selenoprotein Genes, Lifestyle, and Risk of Colon and Rectal Cancer

(2012) Martha L. Slattery et al.   PLoS One

Phase 3 clinical trial investigating the effect of selenium supplementation in men at high-risk for prostate cancer

(2012) Amit M. Algotar et al.   PROSTATE

The need for a reassessment of the safe upper limit of selenium in drinking water

(2012) Marco Vinceti et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Designing the selenium and bladder cancer trial (SELEBLAT), a phase lll randomized chemoprevention study with selenium on recurrence of bladder cancer in Belgium

(2012) Maria E Goossens et al.   BMC Urology

Dietary selenomethionine exposure in adult zebrafish alters swimming performance, energetics and the physiological stress response

(2011) J.K. Thomas et al.   AQUATIC TOXICOLOGY

Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds

(2011) Cristina W. Nogueira et al.   ARCHIVES OF TOXICOLOGY

Heart healthy=prostate healthy: SELECT, the symbolic end of preventing prostate cancer via heart unhealthy and over anti-oxidation mechanisms?

(2011) Mark A Moyad   ASIAN JOURNAL OF ANDROLOGY

Dietary Exposure Estimates of 14 Trace Elements in Xuanwei and Fuyuan, Two High Lung Cancer Incidence Areas in China

(2011) Linlin Zhang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Serum Selenium, Genetic Variation in Selenoenzymes, and Risk of Colorectal Cancer: Primary Analysis from the Women's Health Initiative Observational Study and Meta-analysis

(2011) Y. Takata et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Phase III Trial of Selenium to Prevent Prostate Cancer in Men with High-grade Prostatic Intraepithelial Neoplasia: SWOG S9917

(2011) J. R. Marshall et al.   Cancer Prevention Research

Selenium interactions and toxicity: a review

(2011) Iwona Zwolak et al.   CELL BIOLOGY AND TOXICOLOGY

Serum selenium level and risk of lung cancer mortality: a 16-year follow-up of the Copenhagen Male Study

(2011) Poul Suadicani et al.   EUROPEAN RESPIRATORY JOURNAL

Relevance of selenoprotein transcripts for selenium status in humans

(2011) Edyta Reszka et al.   Genes and Nutrition

Serum selenium and single-nucleotide polymorphisms in genes for selenoproteins: relationship to markers of oxidative stress in men from Auckland, New Zealand

(2011) Nishi Karunasinghe et al.   Genes and Nutrition

Vitamin E and the Risk of Prostate Cancer

(2011) Eric A. Klein et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Reduced Utilization of Selenium by Naked Mole Rats Due to a Specific Defect in GPx1 Expression

(2011) Marina V. Kasaikina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progression From High-Grade Prostatic Intraepithelial Neoplasia to Cancer: A Randomized Trial of Combination Vitamin-E, Soy, and Selenium

(2011) Neil E. Fleshner et al.   JOURNAL OF CLINICAL ONCOLOGY

Low levels of selenium compounds are selectively toxic for a human neuron cell line through ROS/RNS increase and apoptotic process activation

(2011) Tullia Maraldi et al.   NEUROTOXICOLOGY

Selenium and the Course of Mild Graves' Orbitopathy

(2011) Claudio Marcocci et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Selenium Supplements on Cancer Prevention: Meta-analysis of Randomized Controlled Trials

(2011) Eun-Hyun Lee et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Methylselenol, a Selenium Metabolite, Plays Common and Different Roles in Cancerous Colon HCT116 Cell and Noncancerous NCM460 Colon Cell Proliferation

(2011) Huawei Zeng et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Risk of Chronic Low-Dose Selenium Overexposure in Humans: Insights From Epidemiology and Biochemistry

(2011) M. Vinceti et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Selenium: a double-edged sword for defense and offence in cancer

(2010) Jela Brozmanová et al.   ARCHIVES OF TOXICOLOGY

A prospective study of dietary selenium intake and risk of type 2 diabetes

(2010) Saverio Stranges et al.   BMC PUBLIC HEALTH

Selenium-Responsive Proteins in the Sera of Selenium-Enriched Yeast-Supplemented Healthy African American and Caucasian Men

(2010) R. Sinha et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Effects of Selenium Status and Polymorphisms in Selenoprotein Genes on Prostate Cancer Risk in a Prospective Study of European Men

(2010) A. Steinbrecher et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Melanoma Chemoprevention in Skin Reconstructs and Mouse Xenografts Using Isoselenocyanate-4

(2010) N. Nguyen et al.   Cancer Prevention Research

A Large Prospective Study of SEP15 Genetic Variation, Interaction with Plasma Selenium Levels, and Prostate Cancer Risk and Survival

(2010) K. L. Penney et al.   Cancer Prevention Research

The relation between amyotrophic lateral sclerosis and inorganic selenium in drinking water: a population-based case-control study

(2010) Marco Vinceti et al.   Environmental Health

Incidence of skin cancers during 5-year follow-up after stopping antioxidant vitamins and mineral supplementation

(2010) Khaled Ezzedine et al.   EUROPEAN JOURNAL OF CANCER

Comparative study of p38 MAPK signal transduction pathway of peripheral blood mononuclear cells from patients with coal-combustion-type fluorosis with and without high hair selenium levels

(2010) Qun Chen et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Soils selenium level and esophageal cancer: An ecological study in a high risk area for esophageal cancer

(2010) Shahryar Semnani et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Methods of assessment of selenium status in humans: a systematic review

(2009) Kate Ashton et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

In vitro evaluation of selenium genotoxic, cytotoxic, and protective effects: a review

(2009) Vanessa Valdiglesias et al.   ARCHIVES OF TOXICOLOGY

Selenoproteins that function in cancer prevention and promotion

(2009) Dolph L. Hatfield et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Synthesis and antitumor properties of selenocoxib-1 against rat prostate adenocarcinoma cells

(2009) Dhimant Desai et al.   INTERNATIONAL JOURNAL OF CANCER

Selenium, Genetic Variation, and Prostate Cancer Risk: Epidemiology Reflects Back on Selenium and Vitamin E Cancer Prevention Trial

(2009) Elizabeth A. Platz et al.   JOURNAL OF CLINICAL ONCOLOGY

Plasma Selenium, Manganese Superoxide Dismutase, and Intermediate- or High-Risk Prostate Cancer

(2009) June M. Chan et al.   JOURNAL OF CLINICAL ONCOLOGY

JEM Spotlight: Metal speciation related to neurotoxicity in humans

(2009) Bernhard Michalke et al.   JOURNAL OF ENVIRONMENTAL MONITORING

Nutritional Prevention of Cancer: New Directions for an Increasingly Complex Challenge

(2009) A. R. Kristal et al.   JNCI-Journal of the National Cancer Institute

Selenium induced changes on rat sciatic nervefibers: Compound action potentials

(2009) M. Ayaz et al.   METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

Speciation analysis of selected metals and determination of their total contents in paired serum and cerebrospinal fluid samples: An approach to investigate the permeability of the human blood-cerebrospinal fluid-barrier

(2008) Volker Nischwitz et al.   ANALYTICA CHIMICA ACTA

High-Dose Sodium Selenite Can Induce Apoptosis of Lymphoma Cells in Adult Patients with Non-Hodgkin’s Lymphoma

(2008) Inas A. Asfour et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Relationship between glaucoma and selenium levels in plasma and aqueous humour

(2008) R L Bruhn et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Vitamin and mineral use and risk of prostate cancer: the case–control surveillance study

(2008) Yuqing Zhang et al.   CANCER CAUSES & CONTROL

Selenium and anticarcinogenesis: underlying mechanisms

(2008) Matthew I Jackson et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Lung cancer risk associated with selenium status is modified in smoking individuals by Sep15 polymorphism

(2008) Ewa Jablonska et al.   EUROPEAN JOURNAL OF NUTRITION

Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers

(2008) Scott M. Lippman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Should Supplemental Antioxidant Administration Be Avoided During Chemotherapy and Radiation Therapy?

(2008) B. D. Lawenda et al.   JNCI-Journal of the National Cancer Institute

The Nutritional Prevention of Cancer: 400 Mcg Per Day Selenium Treatment

(2008) Mary Reid et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL