Toward Understanding Success and Failures in the Use of Selenium for Cancer Prevention

Supplementation of healthy volunteers with nutritionally relevant amounts of selenium increases the expression of lymphocyte protein biosynthesis genes

(2018) Vasileios Pagmantidis et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Selenium and prostate cancer: systematic review and meta-analysis

(2012) Rachel Hurst et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The influence of selenium and selenoprotein gene variants on colorectal cancer risk

(2012) C. Meplan et al.   MUTAGENESIS

A Randomized Trial of Selenium Supplementation and Risk of Type-2 Diabetes, as Assessed by Plasma Adiponectin

(2012) Margaret P. Rayman et al.   PLoS One

Chemoprevention of prostate cancer: an updated view

(2012) Eric A. Klein et al.   WORLD JOURNAL OF UROLOGY

Prostatic Response to Supranutritional Selenium Supplementation: Comparison of the Target Tissue Potency of Selenomethionine vs. Selenium-Yeast on Markers of Prostatic Homeostasis

(2012) David Waters et al.   Nutrients

Glutathione peroxidase-3 produced by the kidney binds to a population of basement membranes in the gastrointestinal tract and in other tissues

(2011) Raymond F. Burk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Role of Selenium in Inflammation and Immunity: From Molecular Mechanisms to Therapeutic Opportunities

(2011) Zhi Huang et al.   ANTIOXIDANTS & REDOX SIGNALING

The influence of selenium-enriched milk proteins and selenium yeast on plasma selenium levels and rectal selenoprotein gene expression in human subjects

(2011) Ying Hu et al.   BRITISH JOURNAL OF NUTRITION

Phase III Trial of Selenium to Prevent Prostate Cancer in Men with High-grade Prostatic Intraepithelial Neoplasia: SWOG S9917

(2011) J. R. Marshall et al.   Cancer Prevention Research

Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply

(2011) Susanne Krehl et al.   CARCINOGENESIS

Akt signalling in health and disease

(2011) Ingeborg Hers et al.   CELLULAR SIGNALLING

Vitamin E and the Risk of Prostate Cancer

(2011) Eric A. Klein et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Induction of Glutathione Peroxidase 4 Expression during Enterocytic Cell Differentiation

(2011) Bodo Speckmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Delaying of insulin signal transduction in skeletal muscle cells by selenium compounds

(2011) Antonio Pinto et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Selenium and the Course of Mild Graves' Orbitopathy

(2011) Claudio Marcocci et al.   NEW ENGLAND JOURNAL OF MEDICINE

Establishing optimal selenium status: results of a randomized, double-blind, placebo-controlled trial

(2010) Rachel Hurst et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Reducing selenoprotein P expression suppresses adipocyte differentiation as a result of increased preadipocyte inflammation

(2010) Yuanyuan Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Selenium in Human Health and Disease

(2010) Susan J. Fairweather-Tait et al.   ANTIOXIDANTS & REDOX SIGNALING

An allosteric Akt inhibitor effectively blocks Akt signaling and tumor growth with only transient effects on glucose and insulin levels in vivo

(2010) Craig Cherrin et al.   CANCER BIOLOGY & THERAPY

Deficiency in the 15-kDa Selenoprotein Inhibits Tumorigenicity and Metastasis of Colon Cancer Cells

(2010) R. Irons et al.   Cancer Prevention Research

Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein

(2010) Wenfeng Fang et al.   CARCINOGENESIS

Genetic variants in selenoprotein genes increase risk of colorectal cancer

(2010) C. Meplan et al.   CARCINOGENESIS

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

(2010) Hirofumi Misu et al.   Cell Metabolism

Antioxidants in the chemoprevention of colorectal cancer and colorectal adenomas in the general population: a systematic review and meta-analysis

(2010) D. Papaioannou et al.   Colorectal Disease

Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction

(2010) Bodo Speckmann et al.   FREE RADICAL BIOLOGY AND MEDICINE

Loss of GPx2 increases apoptosis, mitosis, and GPx1 expression in the intestine of mice

(2010) Simone Florian et al.   FREE RADICAL BIOLOGY AND MEDICINE

Polymorphisms in the selenoprotein S and 15-kDa selenoprotein genes are associated with altered susceptibility to colorectal cancer

(2010) Alison Sutherland et al.   Genes and Nutrition

High selenium intake and increased diabetes risk: experimental evidence for interplay between selenium and carbohydrate metabolism

(2010) Holger Steinbrenner et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Mutations in the selenocysteine insertion sequence–binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

(2010) Erik Schoenmakers et al.   JOURNAL OF CLINICAL INVESTIGATION

Dietary Supplement Use in the United States, 2003–2006

(2010) Regan L. Bailey et al.   JOURNAL OF NUTRITION

Sep15, a Thioredoxin-like Selenoprotein, Is Involved in the Unfolded Protein Response and Differentially Regulated by Adaptive and Acute ER Stresses

(2009) Vyacheslav M. Labunskyy et al.   BIOCHEMISTRY

Glutathione peroxidases in different stages of carcinogenesis

(2009) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selenoproteins that function in cancer prevention and promotion

(2009) Dolph L. Hatfield et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Molecular mechanisms by which selenoproteins affect cancer risk and progression

(2009) Pin Zhuo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selenoproteins and human health: Insights from epidemiological data

(2009) Margaret P. Rayman   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Protection against reactive oxygen species by selenoproteins

(2009) Holger Steinbrenner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selenoprotein P—Expression, functions, and roles in mammals

(2009) Raymond F. Burk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

RE: Lessons from the selenium and vitamin E cancer prevention trial (SELECT)

(2009) Gerhard N. Schrauzer   CRITICAL REVIEWS IN BIOTECHNOLOGY

Selenium and diabetes: an enigma?

(2009) Andreas S. Mueller et al.   FREE RADICAL RESEARCH

Total and Cancer Mortality After Supplementation With Vitamins and Minerals: Follow-up of the Linxian General Population Nutrition Intervention Trial

(2009) Y.-L. Qiao et al.   JNCI-Journal of the National Cancer Institute

The Outcome of Selenium and Vitamin E Cancer Prevention Trial (SELECT) Reveals the Need for Better Understanding of Selenium Biology

(2009) D. L. Hatfield et al.   MOLECULAR INTERVENTIONS

Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon

(2009) Anna Kipp et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Selenium, Folate, and Colon Cancer

(2009) Alexandra Connelly-Frost et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease

(2009) Arthur Kaser et al.   SEMINARS IN IMMUNOLOGY

Thioredoxin reductase 1 ablation sensitizes colon cancer cells to methylseleninate-mediated cytotoxicity

(2009) Matthew Honeggar et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Variation in the Selenoenzyme Genes and Risk of Advanced Distal Colorectal Adenoma

(2008) U. Peters et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Suppression of Colorectal Oncogenesis by Selenium-Enriched Milk Proteins: Apoptosis and K-ras Mutations

(2008) Y. Hu et al.   CANCER RESEARCH

Selenium and cancer: biomarkers of selenium status and molecular action of selenium supplements

(2008) Jolanta Gromadzińska et al.   EUROPEAN JOURNAL OF NUTRITION

Selenoprotein P expression is controlled through interaction of the coactivator PGC-1α with FoxO1a and hepatocyte nuclear factor 4α transcription factors

(2008) Bodo Speckmann et al.   HEPATOLOGY

Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers

(2008) Scott M. Lippman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Selenoproteins

(2008) Jun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer

(2008) Tianhong Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Aberrant expression of selenoproteins in the progression of colorectal cancer

(2007) Yoshiyuki Murawaki et al.   CANCER LETTERS