Lipid metabolism in skeletal muscle: generation of adaptive and maladaptive intracellular signals for cellular function
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Title
Lipid metabolism in skeletal muscle: generation of adaptive and maladaptive intracellular signals for cellular function
Authors
Keywords
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Journal
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Volume 302, Issue 11, Pages E1315-E1328
Publisher
American Physiological Society
Online
2011-12-21
DOI
10.1152/ajpendo.00561.2011
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Note: Only part of the references are listed.- Exercise increases plasma levels of sphingoid base-1 phosphates in humans
- (2011) M. Baranowski et al. Acta Physiologica
- FATP4 contributes as an enzyme to the basal and insulin-mediated fatty acid uptake of C2C12 muscle cells
- (2011) Margarete Digel et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- A single prior bout of exercise protects against palmitate-induced insulin resistance despite an increase in total ceramide content
- (2011) A. Brianne Thrush et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Thermodynamics and Mechanics of Membrane Curvature Generation and Sensing by Proteins and Lipids
- (2011) Tobias Baumgart et al. Annual Review of Physical Chemistry
- Sphingolipid Metabolism, Oxidant Signaling, and Contractile Function of Skeletal Muscle
- (2011) Mariana N. Nikolova-Karakashian et al. ANTIOXIDANTS & REDOX SIGNALING
- FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation
- (2011) Brennan K. Smith et al. BIOCHEMICAL JOURNAL
- Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
- (2011) Maria M. Mihaylova et al. CELL
- Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype
- (2011) Maryam Ahmadian et al. Cell Metabolism
- Pigment Epithelium-Derived Factor Regulates Lipid Metabolism via Adipose Triglyceride Lipase
- (2011) M. L. Borg et al. DIABETES
- Altered Skeletal Muscle Lipase Expression and Activity Contribute to Insulin Resistance in Humans
- (2011) P.-M. Badin et al. DIABETES
- Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?
- (2011) F. Amati et al. DIABETES
- Unique Regulation of Adipose Triglyceride Lipase (ATGL) by Perilipin 5, a Lipid Droplet-associated Protein
- (2011) Hong Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Monoglyceride Lipase Deficiency in Mice Impairs Lipolysis and Attenuates Diet-induced Insulin Resistance
- (2011) Ulrike Taschler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Carnitine Palmitoyltransferase 1a (CPT1a) Is Part of an Outer Membrane Fatty Acid Transfer Complex
- (2011) Kwangwon Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Murine Diacylglycerol Acyltransferase-2 (DGAT2) Can Catalyze Triacylglycerol Synthesis and Promote Lipid Droplet Formation Independent of Its Localization to the Endoplasmic Reticulum
- (2011) Pamela J. McFie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants
- (2011) Mariel M Finucane et al. LANCET
- Gastric Bypass Surgery Reduces Plasma Ceramide Subspecies and Improves Insulin Sensitivity in Severely Obese Patients
- (2011) Hazel Huang et al. Obesity
- Deficiency of the Mitochondrial Electron Transport Chain in Muscle Does Not Cause Insulin Resistance
- (2011) Dong-Ho Han et al. PLoS One
- Lipins: Multifunctional Lipid Metabolism Proteins
- (2010) Lauren S. Csaki et al. Annual Review of Nutrition
- The G0/G1 Switch Gene 2 Regulates Adipose Lipolysis through Association with Adipose Triglyceride Lipase
- (2010) Xingyuan Yang et al. Cell Metabolism
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- (2010) Elisabetta Meacci et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
- (2010) J. R. Ussher et al. DIABETES
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- (2010) C. R. Benton et al. DIABETOLOGIA
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- (2010) Branka Stancevic et al. FEBS LETTERS
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- (2010) Sophie Turban et al. FEBS LETTERS
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- (2010) James G. Granneman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Jill A. Bell et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2010) Lide Arana et al. Lipids in Health and Disease
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- (2010) Erin L. Seifert et al. PLoS One
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- (2009) Erin L. Seifert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Hong Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TIP47 functions in the biogenesis of lipid droplets
- (2009) Anna V. Bulankina et al. JOURNAL OF CELL BIOLOGY
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- (2009) L. Formigli et al. JOURNAL OF CELL SCIENCE
- Adipocyte Differentiation-Related Protein and OXPAT in Rat and Human Skeletal Muscle: Involvement in Lipid Accumulation and Type 2 Diabetes Mellitus
- (2009) Ronnie Minnaard et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
- (2009) Ethan J. Anderson et al. JOURNAL OF CLINICAL INVESTIGATION
- FAT/CD36 is localized in sarcolemma and in vesicle-like structures in subsarcolemma regions but not in mitochondria
- (2009) Jacob Jeppesen et al. JOURNAL OF LIPID RESEARCH
- Novel role of FATP1 in mitochondrial fatty acid oxidation in skeletal muscle cells
- (2009) David Sebastián et al. JOURNAL OF LIPID RESEARCH
- Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity
- (2009) Wei Hu et al. JOURNAL OF LIPID RESEARCH
- Relationship between plasma free fatty acid, intramyocellular triglycerides and long-chain acylcarnitines in resting humans
- (2009) Jill A. Kanaley et al. JOURNAL OF PHYSIOLOGY-LONDON
- The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions
- (2009) T. K. O’Neil et al. JOURNAL OF PHYSIOLOGY-LONDON
- The Effect of Aging on Human Skeletal Muscle Mitochondrial and Intramyocellular Lipid Ultrastructure
- (2009) J. D. Crane et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The stoichiometry of protein phosphorylation in adipocyte lipid droplets: Analysis by N-terminal isotope tagging and enzymatic dephosphorylation
- (2009) Evgeny Kanshin et al. PROTEOMICS
- Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited
- (2008) John J. Dubé et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Inhibition of ADRP prevents diet-induced insulin resistance
- (2008) Gladys M. Varela et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Regulation and function of triacylglycerol lipases in cellular metabolism
- (2008) Matthew J. Watt et al. BIOCHEMICAL JOURNAL
- Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells
- (2008) Maria L. Watson et al. BIOCHEMICAL JOURNAL
- Two pathways for lysophosphatidic acid production
- (2008) J AOKI BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Downregulation of Diacylglycerol Kinase Delta Contributes to Hyperglycemia-Induced Insulin Resistance
- (2008) Alexander V. Chibalin et al. CELL
- Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
- (2008) Timothy R. Koves et al. Cell Metabolism
- Pleiotropic effects of sphingolipids in skeletal muscle
- (2008) P. Bruni et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet-Induced Insulin Resistance
- (2008) C. R. Bruce et al. DIABETES
- AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5
- (2008) S. L. McGee et al. DIABETES
- Fatty Acid Incubation of Myotubes From Humans With Type 2 Diabetes Leads to Enhanced Release of -Oxidation Products Because of Impaired Fatty Acid Oxidation: Effects of Tetradecylthioacetic Acid and Eicosapentaenoic Acid
- (2008) A. J. Wensaas et al. DIABETES
- Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance
- (2008) J. M. Haus et al. DIABETES
- Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects
- (2008) S. M. Reyna et al. DIABETES
- Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients
- (2008) H. Boon et al. DIABETOLOGIA
- Glycerolipid Metabolism and Signaling in Health and Disease
- (2008) Marc Prentki et al. ENDOCRINE REVIEWS
- Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights fromin VivoManipulation of Sphingolipid Metabolism
- (2008) William L. Holland et al. ENDOCRINE REVIEWS
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- (2008) James G. Granneman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Agnieszka Błachnio-Zabielska et al. JOURNAL OF CELLULAR BIOCHEMISTRY
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- (2008) Mandeep P. Gaidhu et al. JOURNAL OF LIPID RESEARCH
- Imaging of Lipid Biosynthesis: How a Neutral Lipid Enters Lipid Droplets
- (2008) Lars Kuerschner et al. TRAFFIC
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