Repurposing old drugs in oncology: Opportunities with clinical and regulatory challenges ahead
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Repurposing old drugs in oncology: Opportunities with clinical and regulatory challenges ahead
Authors
Keywords
-
Journal
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-09-16
DOI
10.1111/jcpt.12759
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metformin-induced anticancer activities: recent insights
- (2018) Stephen Safe et al. BIOLOGICAL CHEMISTRY
- Inventing new therapies without reinventing the wheel: the power of drug repurposing
- (2018) Andreas Papapetropoulos et al. BRITISH JOURNAL OF PHARMACOLOGY
- Hyperglycaemia and Survival in Solid Tumours: A Systematic Review and Meta-analysis
- (2018) R. Barua et al. CLINICAL ONCOLOGY
- A bibliometric review of drug repurposing
- (2018) Nancy C. Baker et al. DRUG DISCOVERY TODAY
- The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells
- (2018) Tereza Cerna et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Survival benefit associated with metformin use in inoperable non-small cell lung cancer patients with diabetes: A population-based retrospective cohort study
- (2018) Min-Chun Chuang et al. PLoS One
- Insulin Receptor Isoforms in Physiology and Disease: An Updated View
- (2017) Antonino Belfiore et al. ENDOCRINE REVIEWS
- Effects of statins on cancer mortality and progression: A systematic review and meta-analysis of 95 cohorts including 1,111,407 individuals
- (2017) Zubing Mei et al. INTERNATIONAL JOURNAL OF CANCER
- The Effect of VPA on Increasing Radiosensitivity in Osteosarcoma Cells and Primary-Culture Cells from Chemical Carcinogen-Induced Breast Cancer in Rats
- (2017) Guochao Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Histone Deacetylase Inhibitors as Anticancer Drugs
- (2017) Tomas Eckschlager et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A phase Ib study of everolimus combined with metformin for patients with advanced cancer
- (2017) Remco J. Molenaar et al. INVESTIGATIONAL NEW DRUGS
- Comparison of the anticancer properties of a novel valproic acid prodrug to leading histone deacetylase inhibitors
- (2017) Nataly Tarasenko et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Do Statins Improve Survival in Small-Cell Lung Cancer?
- (2017) Sanjay Popat JOURNAL OF CLINICAL ONCOLOGY
- Multicenter, Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Pravastatin Added to First-Line Standard Chemotherapy in Small-Cell Lung Cancer (LUNGSTAR)
- (2017) Michael J. Seckl et al. JOURNAL OF CLINICAL ONCOLOGY
- Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53
- (2017) Manuela Terranova-Barberio et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Psychotropic drugs and ventricular repolarisation: The effects on QT interval, T-peak to T-end interval and QT dispersion
- (2017) Tiziano Acciavatti et al. JOURNAL OF PSYCHOPHARMACOLOGY
- The Effect of Metformin Use during Docetaxel Chemotherapy on Prostate Cancer Specific and Overall Survival of Diabetic Patients with Castration Resistant Prostate Cancer
- (2017) Michelle J. Mayer et al. JOURNAL OF UROLOGY
- Systematic review and meta-analysis of the effect of metformin treatment on overall mortality rates in women with endometrial cancer and type 2 diabetes mellitus
- (2017) Faustino R. Perez-Lopez et al. MATURITAS
- No association between metformin use and survival in patients with pancreatic cancer
- (2017) Martine A. Frouws et al. MEDICINE
- Meta-analysis of studies using metformin as a reducer for liver cancer risk in diabetic patients
- (2017) Shujuan Ma et al. MEDICINE
- The Combination of Metformin and Valproic Acid Induces Synergistic Apoptosis in the Presence of p53 and Androgen Signaling in Prostate Cancer
- (2017) Linh N.K. Tran et al. MOLECULAR CANCER THERAPEUTICS
- Acquired long QT syndrome and phosphoinositide 3-kinase
- (2017) Ira S. Cohen et al. TRENDS IN CARDIOVASCULAR MEDICINE
- The combination astemizole–gefitinib as a potential therapy for human lung cancer
- (2017) María de Guadalupe Chávez-López et al. OncoTargets and Therapy
- CHK2 is involved in the p53-independent radiosensitizing effects of valproic acid
- (2017) Dong Wan Choo et al. Oncology Letters
- Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells
- (2017) Maria Saveria Gilardini Montani et al. CELLULAR ONCOLOGY
- Metformin: a review of its potential indications
- (2017) Yi-Wei Wang et al. Drug Design Development and Therapy
- Valproic acid inhibits glioblastoma multiforme cell growth via paraoxonase 2 expression
- (2017) Jen-Ho Tseng et al. Oncotarget
- The impact of metformin use on survival in prostate cancer: a systematic review and meta-analysis
- (2017) Yao Xiao et al. Oncotarget
- HDAC inhibition as a treatment concept to combat temsirolimus-resistant bladder cancer cells
- (2017) Eva Juengel et al. Oncotarget
- Phenformin has anti-tumorigenic effects in human ovarian cancer cells and in an orthotopic mouse model of serous ovarian cancer
- (2017) Amanda L. Jackson et al. Oncotarget
- HDAC inhibitors enhance the immunotherapy response of melanoma cells
- (2017) Laurence Booth et al. Oncotarget
- Metformin Use Is Associated with Reduced Incidence and Improved Survival of Endometrial Cancer: A Meta-Analysis
- (2017) Yun-Liang Tang et al. Biomed Research International
- Metformin Improves Overall Survival of Colorectal Cancer Patients with Diabetes: A Meta-Analysis
- (2017) Fanqiang Meng et al. Journal of Diabetes Research
- Metformin in Lung Cancer: Review of in Vitro and in Vivo Animal Studies
- (2017) Michael Yousef et al. Cancers
- Roles of Valproic Acid in Improving Radiation Therapy for Glioblastoma: a Review of Literature Focusing on Clinical Evidence
- (2016) Satoru Ochiai et al. Asian Pacific Journal of Cancer Prevention
- Phase II clinical study of valproic acid plus cisplatin and cetuximab in recurrent and/or metastatic squamous cell carcinoma of Head and Neck-V-CHANCE trial
- (2016) Francesco Caponigro et al. BMC CANCER
- Approaching a Scientific Consensus on the Association between Allergies and Glioma Risk: A Report from the Glioma International Case-Control Study
- (2016) E. S. Amirian et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Metformin for Reducing Racial/Ethnic Difference in Prostate Cancer Incidence for Men with Type II Diabetes
- (2016) C.-P. Wang et al. Cancer Prevention Research
- Valproic acid inhibits the angiogenic potential of cervical cancer cells via HIF-1α/VEGF signals
- (2016) Y. Zhao et al. Clinical & Translational Oncology
- hERG Channels: From Antitargets to Novel Targets for Cancer Therapy
- (2016) Annarosa Arcangeli et al. CLINICAL CANCER RESEARCH
- Administration of Non-Torsadogenic human Ether-à-go-go-Related Gene Inhibitors Is Associated with Better Survival for High hERG–Expressing Glioblastoma Patients
- (2016) Kelli B. Pointer et al. CLINICAL CANCER RESEARCH
- A phase II trial of valproic acid in patients with advanced, radioiodine-resistant thyroid cancers of follicular cell origin
- (2016) Naris Nilubol et al. CLINICAL ENDOCRINOLOGY
- Repurposing Vitamin D as an Anticancer Drug
- (2016) D.C. Gilbert et al. CLINICAL ONCOLOGY
- Hyperglycaemia Induced by Novel Anticancer Agents: An Undesirable Complication or a Potential Therapeutic Opportunity?
- (2016) Rashmi R. Shah DRUG SAFETY
- Tyrosine Kinase Inhibitor-Induced Interstitial Lung Disease: Clinical Features, Diagnostic Challenges, and Therapeutic Dilemmas
- (2016) Rashmi R. Shah DRUG SAFETY
- Valproic acid reduces hair loss and improves survival in patients receiving temozolomide-based radiation therapy for high-grade glioma
- (2016) Shinichi Watanabe et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Risk of severe rash in cancer patients treated with EGFR tyrosine kinase inhibitors: a systematic review and meta-analysis
- (2016) Xi Zhang et al. Future Oncology
- Prospective study of Type 2 diabetes mellitus, anti-diabetic drugs and risk of prostate cancer
- (2016) Christel Häggström et al. INTERNATIONAL JOURNAL OF CANCER
- Valproic Acid as a Promising Co-Treatment With Paclitaxel and Doxorubicin in Different Ovarian Carcinoma Cell Lines
- (2016) Patrycja Kwiecińska et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Valproic acid enhances the antileukemic effect of cytarabine by triggering cell apoptosis
- (2016) NAN LIU et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Metformin in pancreatic cancer treatment: from clinical trials through basic research to biomarker quantification
- (2016) Archana Bhaw-Luximon et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Metformin enhances the response to radiotherapy in diabetic patients with rectal cancer
- (2016) Bo Young Oh et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Metformin Use Is Associated with Improved Survival in Patients Undergoing Resection for Pancreatic Cancer
- (2016) Marcelo Cerullo et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide
- (2016) Navid Redjal et al. JOURNAL OF NEURO-ONCOLOGY
- Does the choice of antiepileptic drug affect survival in glioblastoma patients?
- (2016) Kristin M. Knudsen-Baas et al. JOURNAL OF NEURO-ONCOLOGY
- Possibility as an anti-cancer drug of astemizole: Evaluation of arrhythmogenicity by the chronic atrioventricular block canine model
- (2016) Hiroko Izumi-Nakaseko et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Metformin Is Associated With Slightly Reduced Risk of Colorectal Cancer and Moderate Survival Benefits in Diabetes Mellitus
- (2016) Xing-kang He et al. MEDICINE
- The Effect of Diabetes Mellitus on Lung Cancer Prognosis
- (2016) Linhai Zhu et al. MEDICINE
- Pharmacogenomics and histone deacetylase inhibitors
- (2016) Andrew KL Goey et al. PHARMACOGENOMICS
- Metformin: An anti-diabetic drug to fight cancer
- (2016) Marie Daugan et al. PHARMACOLOGICAL RESEARCH
- Repurposing old drugs to chemoprevention: the case of metformin
- (2016) Brandy M. Heckman-Stoddard et al. SEMINARS IN ONCOLOGY
- Histone Deacetylase Inhibitors Prolong Cardiac Repolarization through Transcriptional Mechanisms
- (2016) Stan Spence et al. TOXICOLOGICAL SCIENCES
- Diabetes mellitus and metformin in hepatocellular carcinoma
- (2016) Koji Fujita et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Integrating subpathway analysis to identify candidate agents for hepatocellular carcinoma
- (2016) Jiye Wang et al. OncoTargets and Therapy
- Valproic acid induces autophagy by suppressing the Akt/mTOR pathway in human prostate cancer cells
- (2016) Qinghua Xia et al. Oncology Letters
- Suppression of the Eag1 potassium channel sensitizes glioblastoma cells to injury caused by temozolomide
- (2016) Thais Torquato Sales et al. Oncology Letters
- Metformin treatment reduces temozolomide resistance of glioblastoma cells
- (2016) Seung Ho Yang et al. Oncotarget
- Insulin, insulin receptors, and cancer
- (2016) R. Vigneri et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- Diabetes and mortality in patients with prostate cancer: a meta-analysis
- (2016) Junga Lee et al. SpringerPlus
- Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment
- (2016) Anne-Marie Ellegaard et al. EBioMedicine
- A pooled multisite analysis of the effects of atopic medical conditions in glioma risk in different ethnic groups
- (2015) Bhuma Krishnamachari et al. ANNALS OF EPIDEMIOLOGY
- Metformin Addition to Chemotherapy in Stage IV Non-Small Cell Lung Cancer: an Open Label Randomized Controlled Study
- (2015) Rana Sayed et al. Asian Pacific Journal of Cancer Prevention
- DECIDER: prospective randomized multicenter phase II trial of low-dose decitabine (DAC) administered alone or in combination with the histone deacetylase inhibitor valproic acid (VPA) and all-trans retinoic acid (ATRA) in patients >60 years with acute myeloid leukemia who are ineligible for induction chemotherapy
- (2015) Olga Grishina et al. BMC CANCER
- (Ir)relevance of Metformin Treatment in Patients with Metastatic Pancreatic Cancer: An Open-Label, Randomized Phase II Trial
- (2015) M. Reni et al. CLINICAL CANCER RESEARCH
- A Multicenter, Open-Label Phase II Study of Metformin With Erlotinib in Second-Line Therapy of Stage IV Non–Small-Cell Lung Cancer Patients: Treatment Rationale and Protocol Dynamics of the METAL Trial
- (2015) Morena Fasano et al. Clinical Lung Cancer
- Prognostic implications of epilepsy in glioblastomas
- (2015) Manuel Toledo et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- Drug repositioning and repurposing: terminology and definitions in literature
- (2015) Joris Langedijk et al. DRUG DISCOVERY TODAY
- Novel perspectives in cancer therapy: Targeting ion channels
- (2015) Annarosa Arcangeli et al. DRUG RESISTANCE UPDATES
- Update on Cardiovascular Safety of Tyrosine Kinase Inhibitors: With a Special Focus on QT Interval, Left Ventricular Dysfunction and Overall Risk/Benefit
- (2015) Rashmi R. Shah et al. DRUG SAFETY
- Inhibition of cytochrome P450 2J2 by tanshinone IIA induces apoptotic cell death in hepatocellular carcinoma HepG2 cells
- (2015) Yu Jin Jeon et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Diabetes, metformin and incidence of and death from invasive cancer in postmenopausal women: Results from the women's health initiative
- (2015) Zhihong Gong et al. INTERNATIONAL JOURNAL OF CANCER
- A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma
- (2015) Andra V. Krauze et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Favorable results after conservative management of 316 valproate intoxicated patients
- (2015) Hossein Hassanian-Moghaddam et al. Journal of Research in Medical Sciences
- Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial
- (2015) Sil Kordes et al. LANCET ONCOLOGY
- Why do oncology drugs fail to gain US regulatory approval?
- (2015) Sean Khozin et al. NATURE REVIEWS DRUG DISCOVERY
- Academic drug discovery within the United Kingdom: a reassessment
- (2015) Emma Shanks et al. NATURE REVIEWS DRUG DISCOVERY
- Prognostic relevance of epilepsy at presentation in glioblastoma patients
- (2015) Sharon Berendsen et al. NEURO-ONCOLOGY
- Association between Prediagnostic Allergy-Related Serum Cytokines and Glioma
- (2015) Judith Schwartzbaum et al. PLoS One
- HDAC Inhibitors as Novel Anti-Cancer Therapeutics
- (2015) Cristabelle Souza et al. Recent Patents on Anti-Cancer Drug Discovery
- A screen of approved drugs and molecular probes identifies therapeutics with anti–Ebola virus activity
- (2015) Lisa M. Johansen et al. Science Translational Medicine
- Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells
- (2015) Dinesh Thotala et al. Oncotarget
- Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression
- (2015) Manuela Terranova-Barberio et al. Oncotarget
- Pharmacologic Therapy of Diabetes and Overall Cancer Risk and Mortality: A Meta-Analysis of 265 Studies
- (2015) Lang Wu et al. Scientific Reports
- Voltage-Gated Ion Channels in Cancer Cell Proliferation
- (2015) Vidhya Rao et al. Cancers
- In Vitro and In Vivo Radiosensitizing Effect of Valproic Acid on Fractionated Irradiation
- (2015) Eui Kyu Chie et al. Cancer Research and Treatment
- In vivo dual targeting of the oncogenic Ether-à-go-go-1 potassium channel by calcitriol and astemizole results in enhanced antineoplastic effects in breast tumors
- (2014) Janice García-Quiroz et al. BMC CANCER
- Long-term use of valproic acid in US veterans is associated with a reduced risk of smoking-related cases of head and neck cancer
- (2014) Hyunseok Kang et al. CANCER
- Metformin: From Mechanisms of Action to Therapies
- (2014) Marc Foretz et al. Cell Metabolism
- Metformin Sensitizes EGFR-TKI-Resistant Human Lung Cancer Cells In Vitro and In Vivo through Inhibition of IL-6 Signaling and EMT Reversal
- (2014) L. Li et al. CLINICAL CANCER RESEARCH
- Could valproic acid be an effective anticancer agent? The evidence so far
- (2014) Seth A Brodie et al. Expert Review of Anticancer Therapy
- Antiproliferative and Proapoptotic Effects of Astemizole on Cervical Cancer Cells
- (2014) María de Guadalupe Chávez-López et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- New and emerging HDAC inhibitors for cancer treatment
- (2014) Alison C. West et al. JOURNAL OF CLINICAL INVESTIGATION
- herg1bExpression as a Potential Specific Marker in Pediatric Acute Myeloid Leukemia Patients with HERG 897K/K Genotype
- (2014) Merve Erdem et al. PEDIATRIC HEMATOLOGY AND ONCOLOGY
- Survival analysis for valproic acid use in adult glioblastoma multiforme: A meta-analysis of individual patient data and a systematic review
- (2014) Yang Yuan et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- The effect of metformin on breast cancer outcomes in patients with type 2 diabetes
- (2014) Bridget A. Oppong et al. Cancer Medicine
- QTc prolongation and valproate toxicity
- (2013) Sara Kazim et al. CLINICAL TOXICOLOGY
- Early Investigation of QTc Liability
- (2013) Rashmi R. Shah et al. DRUG SAFETY
- Hepatotoxicity of Tyrosine Kinase Inhibitors: Clinical and Regulatory Perspectives
- (2013) Rashmi R. Shah et al. DRUG SAFETY
- Dealing with Global Safety Issues
- (2013) Norman Stockbridge et al. DRUG SAFETY
- Cardiovascular Safety of Tyrosine Kinase Inhibitors: With a Special Focus on Cardiac Repolarisation (QT Interval)
- (2013) Rashmi R. Shah et al. DRUG SAFETY
- Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor—H1/H4 receptor selectivity
- (2013) Eva Wagner et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Metformin Is Associated With Survival Benefit in Cancer Patients With Concurrent Type 2 Diabetes: A Systematic Review and Meta-Analysis
- (2013) M. Yin et al. ONCOLOGIST
- Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review
- (2013) Monica Franciosi et al. PLoS One
- Phenformin enhances the therapeutic benefit of BRAFV600E inhibition in melanoma
- (2013) P. Yuan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Medical genetic inspirations for anticancer drug repurposing
- (2013) Zhong-Yi Wang et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Allergic conditions reduce the risk of glioma: a meta-analysis based on 128,936 subjects
- (2013) Hongyu Zhao et al. TUMOR BIOLOGY
- Teaching an Old Dog New Tricks: Drug Repositioning in Small Cell Lung Cancer
- (2013) J. Wang et al. Cancer Discovery
- A history of the role of the hERG channel in cardiac risk assessment
- (2013) David Rampe et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents
- (2013) Hanne Fredly et al. Clinical Epigenetics
- Astemizole: an Old Anti-histamine as a New Promising Anti-cancer Drug
- (2012) Janice Garcia-Quiroz et al. Anti-Cancer Agents in Medicinal Chemistry
- Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results
- (2012) Sharon Berendsen et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- The Price We Pay for Progress: A Meta-Analysis of Harms of Newly Approved Anticancer Drugs
- (2012) Saroj Niraula et al. JOURNAL OF CLINICAL ONCOLOGY
- Astemizole Synergizes Calcitriol Antiproliferative Activity by Inhibiting CYP24A1 and Upregulating VDR: A Novel Approach for Breast Cancer Therapy
- (2012) Janice García-Quiroz et al. PLoS One
- Suppression of Phosphoinositide 3-Kinase Signaling and Alteration of Multiple Ion Currents in Drug-Induced Long QT Syndrome
- (2012) Z. Lu et al. Science Translational Medicine
- Understanding the benefit of metformin use in cancer treatment
- (2011) Ryan JO Dowling et al. BMC Medicine
- Oncogenic Targets, Magnitude of Benefit, and Market Pricing of Antineoplastic Drugs
- (2011) Eitan Amir et al. JOURNAL OF CLINICAL ONCOLOGY
- Prediagnostic Plasma IgE Levels and Risk of Adult Glioma in Four Prospective Cohort Studies
- (2011) F. C. F. Calboli et al. JNCI-Journal of the National Cancer Institute
- Targeting the Phosphoinositide-3 (PI3) Kinase Pathway in Breast Cancer
- (2011) J. Baselga ONCOLOGIST
- Eag and HERG potassium channels as novel therapeutic targets in cancer
- (2011) Viren Asher et al. World Journal of Surgical Oncology
- Novel roles for hERG K+ channels in cell proliferation and apoptosis
- (2011) J Jehle et al. Cell Death & Disease
- Expression and significance of HERG protein in gastric cancer
- (2010) Xiao-Dong Shao et al. CANCER BIOLOGY & THERAPY
- The Eag potassium channel as a new prognostic marker in ovarian cancer
- (2010) Viren Asher et al. Diagnostic Pathology
- Allergy and risk of glioma: a meta-analysis
- (2010) C. Chen et al. EUROPEAN JOURNAL OF NEUROLOGY
- Effects of antihistamine and anti-inflammatory medication use on risk of specific glioma histologies
- (2010) Michael E. Scheurer et al. INTERNATIONAL JOURNAL OF CANCER
- Molecular and Therapeutic Potential and Toxicity of Valproic Acid
- (2010) Sébastien Chateauvieux et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Diabetes and prognosis in a breast cancer cohort
- (2010) Michael G. Schrauder et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Cytochrome P450 2J2 Is Highly Expressed in Hematologic Malignant Diseases and Promotes Tumor Cell Growth
- (2010) C. Chen et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A phase I–II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma
- (2009) A Rocca et al. BRITISH JOURNAL OF CANCER
- Clinical and Biological Effects of Valproic Acid as a Histone Deacetylase Inhibitor on Tumor and Surrogate Tissues: Phase I/II Trial of Valproic acid and Epirubicin/FEC
- (2009) P. Munster et al. CLINICAL CANCER RESEARCH
- Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes: ZODIAC-16
- (2009) G. W.D. Landman et al. DIABETES CARE
- Calcitriol inhibits Ether-à go-go potassium channel expression and cell proliferation in human breast cancer cells
- (2009) Rocío García-Becerra et al. EXPERIMENTAL CELL RESEARCH
- IgE, allergy, and risk of glioma: Update from the San Francisco Bay Area Adult Glioma Study in the Temozolomide era
- (2009) Joseph L. Wiemels et al. INTERNATIONAL JOURNAL OF CANCER
- Interactions of Histamine H1-Receptor Agonists and Antagonists with the Human Histamine H4-Receptor
- (2009) K.-F. Deml et al. MOLECULAR PHARMACOLOGY
- Statins and cancer: A systematic review and meta-analysis
- (2008) Jaana Kuoppala et al. EUROPEAN JOURNAL OF CANCER
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started