Depletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathway

The N-terminal acetyltransferase Naa10 is essential for zebrafish development

(2015) R. Ree et al.   BIOSCIENCE REPORTS

Mitochondrial apoptosis: killing cancer using the enemy within

(2015) J Lopez et al.   BRITISH JOURNAL OF CANCER

A Time to Kill: Targeting Apoptosis in Cancer

(2015) Jean Koff et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Developmental roles of protein N-terminal acetylation

(2015) Rui D. Silva et al.   PROTEOMICS

Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway

(2015) S.-E. Park et al.   SCIENCE

The Molecular Basis for Histone H4- and H2A-Specific Amino-Terminal Acetylation by NatD

(2015) Robert S. Magin et al.   STRUCTURE

An Organellar Nα-Acetyltransferase, Naa60, Acetylates Cytosolic N Termini of Transmembrane Proteins and Maintains Golgi Integrity

(2015) Henriette Aksnes et al.   Cell Reports

Functional repair of p53 mutation in colorectal cancer cells using trans-splicing

(2015) Xingxing He et al.   Oncotarget

ASaccharomyces cerevisiaeModel RevealsIn VivoFunctional Impairment of the Ogden Syndrome N-Terminal Acetyltransferase NAA10 Ser37Pro Mutant

(2014) Petra Van Damme et al.   MOLECULAR & CELLULAR PROTEOMICS

New roles for old modifications: Emerging roles of N-terminal post-translational modifications in development and disease

(2014) John G. Tooley et al.   PROTEIN SCIENCE

Design, Synthesis, and Kinetic Characterization of Protein N-Terminal Acetyltransferase Inhibitors

(2013) Håvard Foyn et al.   ACS Chemical Biology

Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis

(2013) Matthew Brentnall et al.   BMC CELL BIOLOGY

Mitochondria: gatekeepers of response to chemotherapy

(2013) Kristopher A. Sarosiek et al.   TRENDS IN CELL BIOLOGY

Caspase Functions in Cell Death and Disease

(2013) D. R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology

Cellular Mechanisms Controlling Caspase Activation and Function

(2013) A. B. Parrish et al.   Cold Spring Harbor Perspectives in Biology

N-alpha-terminal Acetylation of Histone H4 Regulates Arginine Methylation and Ribosomal DNA Silencing

(2013) Vassia Schiza et al.   PLoS Genetics

N-terminal acetylation and other functions of Nα-acetyltransferases

(2012) Jolien Hollebeke et al.   BIOLOGICAL CHEMISTRY

PARPs and the DNA damage response

(2012) F. G. Sousa et al.   CARCINOGENESIS

Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis

(2012) Yang Liu et al.   JOURNAL OF LIPID RESEARCH

Protein N-terminal acetyltransferases in cancer

(2012) T V Kalvik et al.   ONCOGENE

Identification of Combinatorial Patterns of Post-Translational Modifications on Individual Histones in the Mouse Brain

(2012) Ry Y. Tweedie-Cullen et al.   PLoS One

Protein N-terminal acetyltransferases: when the start matters

(2012) Kristian K. Starheim et al.   TRENDS IN BIOCHEMICAL SCIENCES

N-α-Acetyltransferase 10 Protein Suppresses Cancer Cell Metastasis by Binding PIX Proteins and Inhibiting Cdc42/Rac1 Activity

(2011) Kuo-Tai Hua et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The Human N-Alpha-Acetyltransferase 40 (hNaa40p/hNatD) Is Conserved from Yeast and N-Terminally Acetylates Histones H2A and H4

(2011) Kristine Hole et al.   PLoS One

Towards a Functional Understanding of Protein N-Terminal Acetylation

(2011) Thomas Arnesen   PLOS BIOLOGY

N-Terminal Acetylation Inhibits Protein Targeting to the Endoplasmic Reticulum

(2011) Gabriella M. A. Forte et al.   PLOS BIOLOGY

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

(2010) Denis Drygin et al.   CANCER RESEARCH

Depletion of the human Nα-terminal acetyltransferase A induces p53-dependent apoptosis and p53-independent growth inhibition

(2010) Darina Gromyko et al.   INTERNATIONAL JOURNAL OF CANCER

hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing

(2010) Chung-Fan Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals

(2010) C.-S. Hwang et al.   SCIENCE

Calorie restriction effects on silencing and recombination at the yeast rDNA

(2009) Daniel L. Smith Jr et al.   AGING CELL

Calorie restriction reduces rDNA recombination independently of rDNA silencing

(2009) Michèle Riesen et al.   AGING CELL

Correlation of Expression of Human Arrest-Defective-1 (hARD1) Protein With Breast Cancer

(2009) Min Yu et al.   CANCER INVESTIGATION

Patt1, a novel protein acetyltransferase that is highly expressed in liver and downregulated in hepatocellular carcinoma, enhances apoptosis of hepatoma cells

(2009) Zhen Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Knockdown of Human N -Terminal Acetyltransferase Complex C Leads to p53-Dependent Apoptosis and Aberrant Human Arl8b Localization

(2009) K. K. Starheim et al.   MOLECULAR AND CELLULAR BIOLOGY

Properties of Nat4, an N -Acetyltransferase of Saccharomyces cerevisiae That Modifies N Termini of Histones H2A and H4

(2009) B. Polevoda et al.   MOLECULAR AND CELLULAR BIOLOGY

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

(2009) T. Arnesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the humanNα-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression

(2008) Kristian K. Starheim et al.   BIOCHEMICAL JOURNAL

Generation of novel monoclonal antibodies and their application for detecting ARD1 expression in colorectal cancer

(2008) Tingting Ren et al.   CANCER LETTERS

Implication of human N-α-acetyltransferase 5 in cellular proliferation and carcinogenesis

(2008) A Ametzazurra et al.   ONCOGENE

Yeast Nα-terminal acetyltransferases are associated with ribosomes

(2007) Bogdan Polevoda et al.   JOURNAL OF CELLULAR BIOCHEMISTRY