Therapeutic potency of pharmacological adenosine receptors agonist/antagonist on cancer cell apoptosis in tumor microenvironment, current status, and perspectives

Metformin suppresses CRC growth by inducing apoptosis via ADORA1

(2017) Bin Lan   Frontiers in Bioscience-Landmark

Targeting A2 adenosine receptors in cancer

(2017) David Allard et al.   IMMUNOLOGY AND CELL BIOLOGY

A3 Adenosine Receptor Agonist Inhibited Survival of Breast Cancer Stem Cells via GLI-1 and ERK1/2 Pathway

(2017) Seyyed Mehdi Jafari et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Therapeutic potentials of adenosine receptors agonists and antagonists in colitis; Current status and perspectives

(2017) Amirhossein Bahreyni et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Adenosine and adenosine receptors in the immunopathogenesis and treatment of cancer

(2017) Mohammad H. Kazemi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Adenosine: An endogenous mediator in the pathogenesis of gynecological cancer

(2017) Amirhossein Bahreyni et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Therapeutic potency of pharmacological adenosine receptor agonist/antagonist in angiogenesis, current status and perspectives

(2017) Amirhossein Bahreyni et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Omega-3 Polyunsaturated Fatty Acids Enhance Cisplatin Efficacy in Gastric Cancer Cells by Inducing Apoptosis via ADORA1

(2016) Hong Sheng et al.   Anti-Cancer Agents in Medicinal Chemistry

Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases

(2016) Bruce N. Cronstein et al.   Nature Reviews Rheumatology

Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?

(2016) Pier Andrea Borea et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

MicroRNA-128b suppresses tumor growth and promotes apoptosis by targeting A2bR in gastric cancer

(2015) Ping Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of A2b adenosine receptor regulates ovarian cancer cell growth: involvement of Bax/Bcl-2 and caspase-3

(2015) Sima Hajiahmadi et al.   Biochemistry and Cell Biology

p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

(2015) J S Long et al.   ONCOGENE

Anticancer effect of adenosine on gastric cancerviadiverse signaling pathways

(2015) Ayako Tsuchiya   WORLD JOURNAL OF GASTROENTEROLOGY

NAD+-Metabolizing Ectoenzymes in Remodeling Tumor–Host Interactions: The Human Myeloma Model

(2015) Alberto Horenstein et al.   Cells

Immunoregulatory activity of adenosine and its role in human cancer progression

(2014) Sylvia Muller-Haegele et al.   Expert Review of Clinical Immunology

Omega-3 PUFAs induce apoptosis of gastric cancer cells via ADORA1

(2014) Hong Sheng   Frontiers in Bioscience-Landmark

Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB-MECA in ovarian cancer cell lines

(2014) Hamideh Abedi et al.   TUMOR BIOLOGY

The Roles of CD73 in Cancer

(2014) Zhao-wei Gao et al.   Biomed Research International

Apoptosis-Related Gene Transcription in Human A549 Lung Cancer Cells via A3Adenosine Receptor

(2013) Hitomi Kamiya et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Extracellular Adenosine Sensing—A Metabolic Cell Death Priming Mechanism Downstream of p53

(2013) Jaclyn S. Long et al.   MOLECULAR CELL

Adenosine receptors as drug targets — what are the challenges?

(2013) Jiang-Fan Chen et al.   NATURE REVIEWS DRUG DISCOVERY

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

A3Adenosine Receptor Mediates Apoptosis in 5637 Human Bladder Cancer Cells by GqProtein/PKC-Dependent AIF Upregulation

(2012) Takeshi Kanno et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Adenosine Induces Apoptosis in SBC-3 Human Lung Cancer Cells through A3Adenosine Receptor-Dependent AMID Upregulation

(2012) Takeshi Kanno et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A3Adenosine Receptor-Mediated p53-Dependent Apoptosis in Lu-65 Human Lung Cancer Cells

(2012) Tai-ichiro Otsuki et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells

(2012) Huiqiang Wang et al.   Journal of Translational Medicine

A3 Adenosine Receptor Mediates Apoptosis in In Vitro RCC4-VHL Human Renal Cancer Cells by Up-Regulating AMID Expression

(2012) Hisao Nagaya et al.   JOURNAL OF UROLOGY

The Adenosine A3 Receptor Agonist Cl-IB-MECA Induces Cell Death Through Ca2+/ROS-Dependent Down Regulation of ERK and Akt in A172 Human Glioma Cells

(2012) Thae Hyun Kim et al.   NEUROCHEMICAL RESEARCH

Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?

(2012) V. Kumar   Purinergic Signalling

NAD+ -metabolizing ecto-enzymes shape tumor-host interactions: The chronic lymphocytic leukemia model

(2011) Tiziana Vaisitti et al.   FEBS LETTERS

Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway

(2011) Mahmoud Aghaei et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

P-glycoprotein mediates resistance to A3 adenosine receptor agonist 2-chloro-N6-(3-iodobenzyl)-adenosine-5′-n-methyluronamide in human leukemia cells

(2011) Petr Mlejnek et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tumor angiogenesis: molecular pathways and therapeutic targets

(2011) Sara M Weis et al.   NATURE MEDICINE

Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3

(2011) Mahmoud Aghaei et al.   PROSTATE

Adenosine receptors and cancer

(2010) Stefania Gessi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Adenosine-induced caspase-3 activation by tuning Bcl-XL/DIABLO/IAP expression in HuH-7 human hepatoma cells

(2010) Dongqin Yang et al.   CELL BIOLOGY AND TOXICOLOGY

Adenosine receptors as drug targets

(2010) Bertil B. Fredholm   EXPERIMENTAL CELL RESEARCH

CD39/ENTPD1 Expression by CD4+Foxp3+ Regulatory T Cells Promotes Hepatic Metastatic Tumor Growth in Mice

(2010) Xiaofeng Sun et al.   GASTROENTEROLOGY

CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver

(2010) S. Cohen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Extracellular adenosine triphosphate and adenosine in cancer

(2010) J Stagg et al.   ONCOGENE

Adenosine receptors interacting proteins (ARIPs): Behind the biology of adenosine signaling

(2009) Francisco Ciruela et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Adenosine suppresses CW2 human colonic cancer growth by inducing apoptosis via A1 adenosine receptors

(2009) Masaru Saito et al.   CANCER LETTERS

Tuning of apoptosis-mediator gene transcription in HepG2 human hepatoma cells through an adenosine signal

(2009) Dongqin Yang et al.   CANCER LETTERS

Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-κB signalling pathway in thyroid cancer cells

(2009) Silvana Morello et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Methionine Metabolism and Liver Disease

(2008) José M. Mato et al.   Annual Review of Nutrition

Regulation of enteric functions by adenosine: Pathophysiological and pharmacological implications

(2008) Luca Antonioli et al.   PHARMACOLOGY & THERAPEUTICS