A p53-Dependent Tumor Suppressor Network Is Induced by Selective miR-125a-5p Inhibition in Multiple Myeloma Cells

A critical role for the NFkB pathway in multiple myeloma

(2015)   Oncotarget

Proteotoxic stress targeted therapy (PSTT)

(2015)   Oncotarget

Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib

(2015) Nickolay Neznanov et al.   Oncotarget

p53 as a target in myeloproliferative neoplasms

(2015) Min Lu et al.   Oncotarget

Bruton’s tyrosine kinase: oncotarget in myeloma

(2015) Yu-Tzu Tai et al.   Oncotarget

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma

(2015) Nicola Amodio et al.   Oncotarget

In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma

(2015) Maria Teresa Di Martino et al.   Oncotarget

Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms

(2015) Jahangir Abdi et al.   Oncotarget

The Epidermal Growth Factor Receptor Responsive miR-125a Represses Mesenchymal Morphology in Ovarian Cancer Cells

(2015) Karen D. Cowden Dahl et al.   NEOPLASIA

MYD88-independent growth and survival effects of Sp1 transactivation in Waldenstrom macroglobulinemia

(2014) M. Fulciniti et al.   BLOOD

Pharmacological targeting of p53 through RITA is an effective antitumoral strategy for malignant pleural mesothelioma

(2014) Domenico Di Marzo et al.   CELL CYCLE

A Positive Role of MicroRNA-15b on Regulation of Osteoblast Differentiation

(2014) S. Vimalraj et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Improved risk stratification in myeloma using a microRNA-based classifier

(2013) Ping Wu et al.   BRITISH JOURNAL OF HAEMATOLOGY

MicroRNA Hsa-miR-125a-3p Activates p53 and Induces Apoptosis in Lung Cancer Cells

(2013) Lili Jiang et al.   CANCER INVESTIGATION

miR-29b

(2013) Leonidas Benetatos   CELL CYCLE

miR-29b induces SOCS-1 expression by promoter demethylation and negatively regulates migration of multiple myeloma and endothelial cells

(2013) Nicola Amodio et al.   CELL CYCLE

Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression

(2013) Megan Murray et al.   CELL CYCLE

New Strategies in the Treatment of Multiple Myeloma

(2013) N. C. Munshi et al.   CLINICAL CANCER RESEARCH

Targeting miR-21 Inhibits In Vitro and In Vivo Multiple Myeloma Cell Growth

(2013) E. Leone et al.   CLINICAL CANCER RESEARCH

Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia

(2013) M. Lionetti et al.   CLINICAL CANCER RESEARCH

From Target Therapy to miRNA Therapeutics of Human Multiple Myeloma: Theoretical and Technological Issues in the Evolving Scenario

(2013) Marco Rossi et al.   CURRENT DRUG TARGETS

Immunologic microenvironment and personalized treatment in multiple myeloma

(2013) Marco Rossi et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Non-coding RNA: a novel opportunity for the personalized treatment of multiple myeloma

(2013) Nicola Amodio et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Targeting p53 by small molecules in hematological malignancies

(2013) Manujendra N Saha et al.   Journal of Hematology & Oncology

Biogenesis, evolution and functional targets of microRNA-125a

(2013) Nicoletta Potenza et al.   MOLECULAR GENETICS AND GENOMICS

Future agents and treatment directions in multiple myeloma

(2013) Enrique M Ocio et al.   Expert Review of Hematology

Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma

(2012) S. Blotta et al.   BLOOD

The emerging functions of the p53-miRNA network in stem cell biology

(2012) Chao-Po Lin et al.   CELL CYCLE

Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: In Vitro and In Vivo Evidence

(2012) M. T. Di Martino et al.   CLINICAL CANCER RESEARCH

Editorial: [Hot Topic: New Approaches in the Treatment of Multiple Myeloma: From Target-based Agents to the New Era of microRNAs (Dedicated to the Memory of Prof. Salvatore Venuta)]

(2012) P. Tassone et al.   CURRENT CANCER DRUG TARGETS

Promises and Challenges of MicroRNA-based Treatment of Multiple Myeloma

(2012) P. Tagliaferri et al.   CURRENT CANCER DRUG TARGETS

Mouse Models as a Translational Platform for the Development of New Therapeutic Agents in Multiple Myeloma

(2012) P. Tassone et al.   CURRENT CANCER DRUG TARGETS

Bone Marrow Microenvironment in Multiple Myeloma Progression

(2012) S. Manier et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Different methylation and MicroRNA expression pattern in male and female familial breast cancer

(2012) Rosamaria Pinto et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA profiling: approaches and considerations

(2012) Colin C. Pritchard et al.   NATURE REVIEWS GENETICS

Ectopic Expression of MiR-125a Inhibits the Proliferation and Metastasis of Hepatocellular Carcinoma by Targeting MMP11 and VEGF

(2012) Qian Bi et al.   PLoS One

MicroRNAs miR-125a and miR-125b constitutively activate the NF- B pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)

(2012) S.-W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1

(2012) N Amodio et al.   Cell Death & Disease

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

(2011) Jianxiang Chi et al.   Biology Direct

Genetic screen identifies microRNA cluster 99b/let-7e/125a as a regulator of primitive hematopoietic cells

(2011) A. Gerrits et al.   BLOOD

Mechanisms of microRNA deregulation in human cancer

(2011) Shan Deng et al.   CELL CYCLE

MicroRNA HSA-miR-125a-5p induces apoptosis by activating p53 in lung cancer cells

(2011) Lili Jiang et al.   EXPERIMENTAL LUNG RESEARCH

Suppressing miRNA-15a/-16 expression by interleukin-6 enhances drug-resistance in myeloma cells

(2011) Mu Hao et al.   Journal of Hematology & Oncology

A unique three-dimensional SCID-polymeric scaffold (SCID-synth-hu) model for in vivo expansion of human primary multiple myeloma cells

(2011) T Calimeri et al.   LEUKEMIA

Human microRNA hsa-miR-125a-5p interferes with expression of hepatitis B virus surface antigen

(2011) N. Potenza et al.   NUCLEIC ACIDS RESEARCH

Oncogenic Role of the E3 Ubiquitin Ligase NEDD4-1, a PTEN Negative Regulator, in Non-Small-Cell Lung Carcinomas

(2010) Nicola Amodio et al.   AMERICAN JOURNAL OF PATHOLOGY

Loss of BRCA1 function increases the antitumor activity of cisplatin against human breast cancer xenografts in vivo

(2010) Pierfrancesco Tassone et al.   CANCER BIOLOGY & THERAPY

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

The tumor suppressor p53: Cancer and aging

(2010) Zhaohui Feng et al.   CELL CYCLE

miR-29b and miR-125a regulate podoplanin and suppress invasion in glioblastoma

(2010) Maria Angelica Cortez et al.   GENES CHROMOSOMES & CANCER

MicroRNA as a new player in the cell cycle

(2010) Dongliang Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling

(2010) N C Gutiérrez et al.   LEUKEMIA

Identification of the transcriptional promoters in the proximal regions of human microRNA genes

(2010) Yue-Sheng Long et al.   MOLECULAR BIOLOGY REPORTS

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

High-risk myeloma is associated with global elevation of miRNAs and overexpression ofEIF2C2/AGO2

(2010) Yiming Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma

(2009) M. Lionetti et al.   BLOOD

MicroRNA 125a and its regulation of the p53 tumor suppressor gene

(2009) Yingjie Zhang et al.   FEBS LETTERS

Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data

(2009) David L. Corcoran et al.   PLoS One

MicroRNA profiling in human medulloblastoma

(2008) Elisabetta Ferretti et al.   INTERNATIONAL JOURNAL OF CANCER

Insights into cellular microRNAs and human immunodeficiency virus type 1 (HIV-1)

(2008) Ajit Kumar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNAs in embryonic stem cells

(2008) Yulei Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNAs: Novel Regulators During the Immune Response

(2008) Yujing Bi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Strategies for profiling MicroRNA expression

(2008) William Kong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

(2008) F. Pichiorri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA