Stress and glucocorticoid receptor transcriptional programming in time and space: Implications for the brain-gut axis

The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation

(2015) Jonathan O. Lipton et al.   CELL

Epigenetic Regulation of Genes That Modulate Chronic Stress-Induced Visceral Pain in the Peripheral Nervous System

(2015) Shuangsong Hong et al.   GASTROENTEROLOGY

Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing

(2015) Diana A. Stavreva et al.   GENOME RESEARCH

Irritable Bowel Syndrome

(2015) William D. Chey et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

HLA-allelotype associations with nevirapine-induced hypersensitivity reactions and hepatotoxicity

(2015) Elena M. Cornejo Castro et al.   Pharmacogenetics and Genomics

Exceptional epigenetics in the brain

(2015) C. Luo et al.   SCIENCE

How Far Can Mice Carry Autism Research?

(2014) Steven E. Hyman   CELL

Epigenetic Signaling in Psychiatric Disorders

(2014) Catherine J. Peña et al.   JOURNAL OF MOLECULAR BIOLOGY

Epigenetic modulation of chronic anxiety and pain by histone deacetylation

(2014) L Tran et al.   MOLECULAR PSYCHIATRY

Expressions of Tight Junction Proteins Occludin and Claudin-1 Are under the Circadian Control in the Mouse Large Intestine: Implications in Intestinal Permeability and Susceptibility to Colitis

(2014) Kyoko Oh-oka et al.   PLoS One

Development and entrainment of the colonic circadian clock during ontogenesis

(2013) Lenka Polidarová et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding

(2013) Ximiao He et al.   BMC GENOMICS

Reprogramming the Chromatin Landscape: Interplay of the Estrogen and Glucocorticoid Receptors at the Genomic Level

(2013) T. B. Miranda et al.   CANCER RESEARCH

C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements

(2013) Lars Grøntved et al.   EMBO JOURNAL

Genome-wide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regions

(2013) A. R. Prickett et al.   GENOME RESEARCH

Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements

(2013) Sivapriya Ramamoorthy et al.   MOLECULAR AND CELLULAR BIOLOGY

Brain-Derived Neurotrophic Factor Signaling Rewrites the Glucocorticoid Transcriptome via Glucocorticoid Receptor Phosphorylation

(2013) W. M. Lambert et al.   MOLECULAR AND CELLULAR BIOLOGY

Complex genomic interactions in the dynamic regulation of transcription by the glucocorticoid receptor

(2013) Tina B. Miranda et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Dexamethasone Induces a Putative Repressor Complex and Chromatin Modifications in the CRH Promoter

(2013) Dharmendra Sharma et al.   MOLECULAR ENDOCRINOLOGY

Corticosterone mediates stress-related increased intestinal permeability in a region-specific manner

(2013) G. Zheng et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Glucocorticoid-mediated Period2 induction delays the phase of circadian rhythm

(2013) Solmi Cheon et al.   NUCLEIC ACIDS RESEARCH

CTCF: the protein, the binding partners, the binding sites and their chromatin loops

(2013) S. J. B. Holwerda et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Determinants of Physiological and Perceived Physiological Stress Reactivity in Children and Adolescents

(2013) Brittany E. Evans et al.   PLoS One

Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation

(2013) Keith C. Summa et al.   PLoS One

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered expression of glucocorticoid receptor and corticotropin-releasing factor in the central amygdala in response to elevated corticosterone

(2012) Lee Tran et al.   BEHAVIOURAL BRAIN RESEARCH

Complex dynamics of transcription regulation

(2012) Diana A. Stavreva et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Differential Glucocorticoid Receptor Exon 1B, 1C, and 1H Expression and Methylation in Suicide Completers with a History of Childhood Abuse

(2012) Benoit Labonte et al.   BIOLOGICAL PSYCHIATRY

Evidence for sequence biases associated with patterns of histone methylation

(2012) Zhong Wang et al.   BMC GENOMICS

A genome-wide signature of glucocorticoid receptor binding in neuronal PC12 cells

(2012) J Annelies E Polman et al.   BMC NEUROSCIENCE

Controlling Long-Range Genomic Interactions at a Native Locus by Targeted Tethering of a Looping Factor

(2012) Wulan Deng et al.   CELL

Cooperativity and complementarity: Synergies in non-classical and classical glucocorticoid signaling

(2012) Ranmal A. Samarasinghe et al.   CELL CYCLE

Glucocorticoid Receptor Gene Polymorphisms and Glucocorticoid Resistance in Inflammatory Bowel Disease: A Meta-Analysis

(2012) Hong-Lin Chen et al.   DIGESTIVE DISEASES AND SCIENCES

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

(2012) C. Cheng et al.   GENOME RESEARCH

Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements

(2012) A. Kundaje et al.   GENOME RESEARCH

Widespread plasticity in CTCF occupancy linked to DNA methylation

(2012) H. Wang et al.   GENOME RESEARCH

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

Glucocorticoid and mineralocorticoid receptor expression in the human hippocampus in major depressive disorder

(2012) Adriana Medina et al.   JOURNAL OF PSYCHIATRIC RESEARCH

The Hypersensitive Glucocorticoid Response Specifically Regulates Period 1 and Expression of Circadian Genes

(2012) T. E. Reddy et al.   MOLECULAR AND CELLULAR BIOLOGY

Analysis of Chromatin Dynamics during Glucocorticoid Receptor Activation

(2012) C. J. Burd et al.   MOLECULAR AND CELLULAR BIOLOGY

How glucocorticoid receptors modulate the activity of other transcription factors: A scope beyond tethering

(2012) Dariusz Ratman et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Insights into Negative Regulation by the Glucocorticoid Receptor from Genome-wide Profiling of Inflammatory Cistromes

(2012) N. Henriette Uhlenhaut et al.   MOLECULAR CELL

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Architecture of the human regulatory network derived from ENCODE data

(2012) Mark B. Gerstein et al.   NATURE

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Epigenetics and chromatin dynamics: a review and a paradigm for functional disorders

(2012) T. Ordog et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Childhood Adversity and Epigenetic Modulation of the Leukocyte Glucocorticoid Receptor: Preliminary Findings in Healthy Adults

(2012) Audrey R. Tyrka et al.   PLoS One

Epigenetic transgenerational inheritance of altered stress responses

(2012) D. Crews et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G9a functions as a molecular scaffold for assembly of transcriptional coactivators on a subset of Glucocorticoid Receptor target genes

(2012) D. Bittencourt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk

(2012) S. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Importance of epigenetic mechanisms in visceral pain induced by chronic water avoidance stress

(2012) L. Tran et al.   PSYCHONEUROENDOCRINOLOGY

Early-life disruption of epigenetic marks may contribute to the origins of mental illness

(2012) Elliot R Lee et al.   Epigenomics

The lasting legacy of social stress on the epigenome of the hypothalamic–pituitary–adrenal axis

(2012) Anke Hoffmann et al.   Epigenomics

Blunted Cortisol Responses to Stress Signal Social and Behavioral Problems Among Maltreated/Bullied 12-Year-Old Children

(2011) Isabelle Ouellet-Morin et al.   BIOLOGICAL PSYCHIATRY

Glucocorticoid Receptor Pathway Components Predict Posttraumatic Stress Disorder Symptom Development: A Prospective Study

(2011) Mirjam van Zuiden et al.   BIOLOGICAL PSYCHIATRY

Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor

(2011) Milan Surjit et al.   CELL

Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism

(2011) Ty C. Voss et al.   CELL

Association Between Early Adverse Life Events and Irritable Bowel Syndrome

(2011) Kara Bradford et al.   Clinical Gastroenterology and Hepatology

Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta

(2011) Amanda C. Filiberto et al.   Epigenetics

Stress and visceral pain: From animal models to clinical therapies

(2011) Muriel Larauche et al.   EXPERIMENTAL NEUROLOGY

Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

(2011) Christine Heim et al.   EXPERIMENTAL NEUROLOGY

Coactivation of GR and NFKB alters the repertoire of their binding sites and target genes

(2011) N. A. S. Rao et al.   GENOME RESEARCH

Primary Generalized Glucocorticoid Resistance and Hypersensitivity

(2011) Evangelia Charmandari   Hormone Research in Paediatrics

Perceived threat predicts the neural sequelae of combat stress

(2011) G A van Wingen et al.   MOLECULAR PSYCHIATRY

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

(2011) Sam John et al.   NATURE GENETICS

Glucocorticoid resistance in Crohn's disease and ulcerative colitis: an association study investigating GR and FKBP5 gene polymorphisms

(2011) P Maltese et al.   PHARMACOGENOMICS JOURNAL

Peripheral CLOCK Regulates Target-Tissue Glucocorticoid Receptor Transcriptional Activity in a Circadian Fashion in Man

(2011) Evangelia Charmandari et al.   PLoS One

Dynamic regulation of glucocorticoid signalling in health and disease

(2011) S. C. Biddie et al.   RHEUMATOLOGY

Cell autonomy and synchrony of suprachiasmatic nucleus circadian oscillators

(2011) Jennifer A. Mohawk et al.   TRENDS IN NEUROSCIENCES

Stress-Related Alterations of Visceral Sensation: Animal Models for Irritable Bowel Syndrome Study

(2011) Muriel Larauche et al.   Journal of Neurogastroenterology and Motility

Chronic Corticosterone Exposure Increases Expression and Decreases Deoxyribonucleic Acid Methylation ofFkbp5in Mice

(2010) Richard S. Lee et al.   ENDOCRINOLOGY

Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses

(2010) Tim F. Oberlander et al.   Epigenetics

Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology

(2010) Rudolf P. Talens et al.   FASEB JOURNAL

Corticosterone Mediates Reciprocal Changes in CB 1 and TRPV1 Receptors in Primary Sensory Neurons in the Chronically Stressed Rat

(2010) Shuangsong Hong et al.   GASTROENTEROLOGY

Allele-specific DNA methylation: beyond imprinting

(2010) B. Tycko   HUMAN MOLECULAR GENETICS

Cellular Processing of the Glucocorticoid Receptor Gene and Protein: New Mechanisms for Generating Tissue-specific Actions of Glucocorticoids

(2010) Robert H. Oakley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoid Receptor Activates PoisedFKBP51Locus through Long-Distance Interactions

(2010) Ville Paakinaho et al.   MOLECULAR ENDOCRINOLOGY

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

High Nucleosome Occupancy Is Encoded at Human Regulatory Sequences

(2010) Desiree Tillo et al.   PLoS One

Effect of childhood physical abuse on cortisol stress response

(2010) Linda L. Carpenter et al.   PSYCHOPHARMACOLOGY

Interactions of the circadian CLOCK system and the HPA axis

(2010) Nancy Nader et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications

(2009) Nancy Nader et al.   FASEB JOURNAL

Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation

(2009) T. E. Reddy et al.   GENOME RESEARCH

Glucocorticoid Receptor Activation of theCiz1-Lcn2Locus by Long Range Interactions

(2009) Ofir Hakim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circadian Rhythm Profiles in Women with Night Eating Syndrome

(2009) Namni Goel et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Nuclear Import of the Glucocorticoid Receptor-hsp90 Complex through the Nuclear Pore Complex Is Mediated by Its Interaction with Nup62 and Importin  

(2009) P. C. Echeverria et al.   MOLECULAR AND CELLULAR BIOLOGY

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

Effects of stress throughout the lifespan on the brain, behaviour and cognition

(2009) Sonia J. Lupien et al.   NATURE REVIEWS NEUROSCIENCE

Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers

(2009) Harri Makkonen et al.   NUCLEIC ACIDS RESEARCH

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

(2009) K. A. Lamia et al.   SCIENCE

Prenatal stress, glucocorticoids and the programming of adult disease

(2009) Elizabeth C. Cottrell   Frontiers in Behavioral Neuroscience

CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features

(2009) Kobby Essien et al.   GENOME BIOLOGY

Epigenetic regulation and fetal programming

(2008) Christine Gicquel et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

The Meter of Metabolism

(2008) Carla B. Green et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat

(2008) S Hong et al.   GUT

Dynamic access of the glucocorticoid receptor to response elements in chromatin

(2008) Anuja A. George et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Association of FKBP5 Polymorphisms and Childhood Abuse With Risk of Posttraumatic Stress Disorder Symptoms in Adults

(2008) Elisabeth B. Binder   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The effect of chronic variable stress on bowel habit and adrenal function in rats

(2008) Yong S Kim et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Interaction of the Glucocorticoid Receptor with the Chromatin Landscape

(2008) Sam John et al.   MOLECULAR CELL

The DNA-encoded nucleosome organization of a eukaryotic genome

(2008) Noam Kaplan et al.   NATURE

Removing Obstacles in Neuroscience Drug Discovery: The Future Path for Animal Models

(2008) Athina Markou et al.   NEUROPSYCHOPHARMACOLOGY

The link between childhood trauma and depression: Insights from HPA axis studies in humans

(2008) Christine Heim et al.   PSYCHONEUROENDOCRINOLOGY