Dynamic regulation of glucocorticoid signalling in health and disease

Neuroendocrine-Immune Interactions in Rheumatoid Arthritis: Mechanisms of Glucocorticoid Resistance

(2017) Marni N. Silverman et al.   NEUROIMMUNOMODULATION

An anti-inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation

(2011) Alexander Rauch et al.   FASEB JOURNAL

The HSP90 Molecular Chaperone Cycle Regulates Cyclical Transcriptional Dynamics of the Glucocorticoid Receptor and Its Coregulatory Molecules CBP/p300 During Ultradian Ligand Treatment

(2011) Becky L. Conway-Campbell et al.   MOLECULAR ENDOCRINOLOGY

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

(2011) Sam John et al.   NATURE GENETICS

Identification of NURR1 as a Mediator of MIF Signaling During Chronic Arthritis

(2010) Jennifer A. Ralph et al.   AMERICAN JOURNAL OF PATHOLOGY

AP-1 overexpression impairs corticosteroid inhibition of collagen production by fibroblasts isolated from asthmatic subjects

(2010) Eric Jacques et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Glucocorticoid-induced leucine zipper is an endogenous antiinflammatory mediator in arthritis

(2010) Elaine Beaulieu et al.   ARTHRITIS AND RHEUMATISM

Glucocorticoids Suppress Bone Formation by Attenuating Osteoblast Differentiation via the Monomeric Glucocorticoid Receptor

(2010) Alexander Rauch et al.   Cell Metabolism

Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors

(2010) Salvador Rodriguez-Nieto et al.   HUMAN MUTATION

Chromatin Architecture and the Regulation of Nuclear Receptor Inducible Transcription

(2010) S. C. Biddie   JOURNAL OF NEUROENDOCRINOLOGY

Glucocorticoid Ultradian Rhythmicity Directs Cyclical Gene Pulsing of the Clock Gene Period 1 in Rat Hippocampus

(2010) B. L . Conway-Campbell et al.   JOURNAL OF NEUROENDOCRINOLOGY

SWI/SNF Has Intrinsic Nucleosome Disassembly Activity that Is Dependent on Adjacent Nucleosomes

(2010) Mekonnen Lemma Dechassa et al.   MOLECULAR CELL

The crucial role of pulsatile activity of the HPA axis for continuous dynamic equilibration

(2010) Stafford L. Lightman et al.   NATURE REVIEWS NEUROSCIENCE

Variation in Transcription Factor Binding Among Humans

(2010) M. Kasowski et al.   SCIENCE

Heritable Individual-Specific and Allele-Specific Chromatin Signatures in Humans

(2010) R. McDaniell et al.   SCIENCE

Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases

(2009) Ilse M. E. Beck et al.   ENDOCRINE REVIEWS

Kinetic Complexity of the Global Response to Glucocorticoid Receptor Action

(2009) Sam John et al.   ENDOCRINOLOGY

Hypothalamic-Pituitary-Adrenal Axis Activation in Obstructive Sleep Apnea: The Effect of Continuous Positive Airway Pressure Therapy

(2009) David E. Henley et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

FoxA1 Binding Directs Chromatin Structure and the Functional Response of a Glucocorticoid Receptor-Regulated Promoter

(2009) S. Belikov et al.   MOLECULAR AND CELLULAR BIOLOGY

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

(2009) Diana A. Stavreva et al.   NATURE CELL BIOLOGY

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

Analysis of individual remodeled nucleosomes reveals decreased histone–DNA contacts created by hSWI/SNF

(2009) Karim Bouazoune et al.   NUCLEIC ACIDS RESEARCH

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

(2009) S. H. Meijsing et al.   SCIENCE

Histone deacetylase-2 and airway disease

(2009) Peter J. Barnes   Therapeutic Advances in Respiratory Disease

Overnight variations in cortisol, interleukin 6, tumour necrosis factor   and other cytokines in people with rheumatoid arthritis

(2008) M G Perry et al.   ANNALS OF THE RHEUMATIC DISEASES

High-Resolution Mapping and Characterization of Open Chromatin across the Genome

(2008) Alan P. Boyle et al.   CELL

Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): a double-blind, randomised controlled trial

(2008) Frank Buttgereit et al.   LANCET

Interaction of the Glucocorticoid Receptor with the Chromatin Landscape

(2008) Sam John et al.   MOLECULAR CELL

Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1

(2008) Yukihiko Aikawa et al.   NATURE BIOTECHNOLOGY

Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip

(2008) Fedik Rahimov et al.   NATURE GENETICS

Glucocorticoid receptor dynamics and gene regulation

(2008) Simon C. Biddie et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Glucocorticoid-induced leucine zipper (GILZ) mediates glucocorticoid action and inhibits inflammatory cytokine-induced COX-2 expression

(2007) Nianlan Yang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Increased Corticosterone Pulse Frequency During Adjuvant-Induced Arthritis and its Relationship to Alterations in Stress Responsiveness

(2003) R. J. Windle et al.   JOURNAL OF NEUROENDOCRINOLOGY