Cyclin-dependent Kinase 8 Module Expression Profiling Reveals Requirement of Mediator Subunits 12 and 13 for Transcription of Serpent-dependent Innate Immunity Genes inDrosophila

Rit subfamily small GTPases: Regulators in neuronal differentiation and survival

(2013) Geng-Xian Shi et al.   CELLULAR SIGNALLING

The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator

(2013) M. A. Davis et al.   GENES & DEVELOPMENT

CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response

(2013) Joanna Bancerek et al.   IMMUNITY

Innexins Ogre and Inx2 are required in glial cells for normal postembryonic development of the Drosophila central nervous system

(2013) C. E. Holcroft et al.   JOURNAL OF CELL SCIENCE

Sox10 Cooperates with the Mediator Subunit 12 during Terminal Differentiation of Myelinating Glia

(2013) M. R. Vogl et al.   JOURNAL OF NEUROSCIENCE

A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction

(2013) Kuang-Lei Tsai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcriptional Networks Controlling the Cell Cycle

(2013) Martin Bonke et al.   G3-Genes Genomes Genetics

Somatic MED12 mutations in uterine leiomyosarcoma and colorectal cancer

(2012) K Kämpjärvi et al.   BRITISH JOURNAL OF CANCER

CDK8 Maintains Tumor Dedifferentiation and Embryonic Stem Cell Pluripotency

(2012) A. S. Adler et al.   CANCER RESEARCH

A Cardiac MicroRNA Governs Systemic Energy Homeostasis by Regulation of MED13

(2012) Chad E. Grueter et al.   CELL

Regulation of lipogenesis by cyclin-dependent kinase 8–mediated control of SREBP-1

(2012) Xiaoping Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional Mediators Kto and Skd Are Involved in the Regulation of the IMD Pathway and Anti-Plasmodium Defense in Anopheles gambiae

(2012) Yang Chen et al.   PLoS One

MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling

(2012) H. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An RNAi screen identifies additional members of the Drosophila Integrator complex and a requirement for cyclin C/Cdk8 in snRNA 3'-end formation

(2012) J. Chen et al.   RNA

Function and regulation of the Mediator complex

(2011) Ronald C Conaway et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Requirements for mediator complex subunits distinguish three classes of notch target genes at the Drosophila wing margin

(2011) Florence Janody et al.   DEVELOPMENTAL DYNAMICS

Identification of target genes for the CDK subunits of the Mediator complex

(2011) Taiki Tsutsui et al.   GENES TO CELLS

GeneProf: analysis of high-throughput sequencing experiments

(2011) Florian Halbritter et al.   NATURE METHODS

Mediator Subunit 12 Is Required for Neutrophil Development in Zebrafish

(2011) Maria-Cristina Keightley et al.   PLoS One

BioMart: driving a paradigm change in biological data management

(2011) A. Kasprzyk   Database-The Journal of Biological Databases and Curation

A novel mutation in MED12 causes FG syndrome (Opitz-Kaveggia syndrome)

(2010) P Rump et al.   CLINICAL GENETICS

Drosophila PQBP1 Regulates Learning Acquisition at Projection Neurons in Aversive Olfactory Conditioning

(2010) T. Tamura et al.   JOURNAL OF NEUROSCIENCE

A Genome-Wide RNA Interference Screen Identifies a Differential Role of the Mediator CDK8 Module Subunits for GATA/ RUNX-Activated Transcription in Drosophila

(2010) Vanessa Gobert et al.   MOLECULAR AND CELLULAR BIOLOGY

Mediator and cohesin connect gene expression and chromatin architecture

(2010) Michael H. Kagey et al.   NATURE

CDK8 is a positive regulator of transcriptional elongation within the serum response network

(2010) Aaron J Donner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

(2009) M. T. Knuesel et al.   GENES & DEVELOPMENT

Identification of a Putative Invertebrate Helical Cytokine Similar to the Ciliary Neurotrophic Factor/Leukemia Inhibitory Factor Family by PSI-BLAST-Based Approach

(2009) Gong Cheng et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Regulation of the Drosophila Enhancer of split and invected-engrailed Gene Complexes by Sister Chromatid Cohesion Proteins

(2009) Cheri A. Schaaf et al.   PLoS One

Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos

(2008) Brian Stramer et al.   EMBO REPORTS

E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8

(2008) Erick J. Morris et al.   NATURE

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

(2008) Ron Firestein et al.   NATURE

Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

(2008) Henri-Marc Bourbon   NUCLEIC ACIDS RESEARCH

Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13

(2008) I. Carrera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA