Requirements for mediator complex subunits distinguish three classes of notch target genes at the Drosophila wing margin

Notch-dependent expression of the archipelago ubiquitin ligase subunit in the Drosophila eye

(2010) S. C. Nicholson et al.   DEVELOPMENT

Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling

(2010) P. P. Rocha et al.   DEVELOPMENT

A Genome-Wide RNA Interference Screen Identifies a Differential Role of the Mediator CDK8 Module Subunits for GATA/ RUNX-Activated Transcription in Drosophila

(2010) Vanessa Gobert et al.   MOLECULAR AND CELLULAR BIOLOGY

Cyclin-Dependent Kinase 8 Positively Cooperates with Mediator To Promote Thyroid Hormone Receptor-Dependent Transcriptional Activation

(2010) M. Belakavadi et al.   MOLECULAR AND CELLULAR BIOLOGY

Differential Regulation of Transcription through Distinct Suppressor of Hairless DNA Binding Site Architectures during Notch Signaling in Proneural Clusters

(2010) J. W. Cave et al.   MOLECULAR AND CELLULAR BIOLOGY

The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation

(2010) Sohail Malik et al.   NATURE REVIEWS GENETICS

CDK8 is a positive regulator of transcriptional elongation within the serum response network

(2010) Aaron J Donner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

(2010) Kelly L Arnett et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The human Mediator complex: a versatile, genome-wide regulator of transcription

(2010) Dylan J. Taatjes   TRENDS IN BIOCHEMICAL SCIENCES

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

(2009) Claudio Alarcón et al.   CELL

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

(2009) M. T. Knuesel et al.   GENES & DEVELOPMENT

Promoter-specific co-activation by Drosophila mastermind

(2008) John W. Cave et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role for Med12 in Regulation ofNanogand Nanog Target Genes

(2008) Antonin V. Tutter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mediator Links Epigenetic Silencing of Neuronal Gene Expression with X-Linked Mental Retardation

(2008) Ning Ding et al.   MOLECULAR CELL

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

(2008) Ron Firestein et al.   NATURE

Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

(2008) Henri-Marc Bourbon   NUCLEIC ACIDS RESEARCH

Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13

(2008) I. Carrera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA